In:
Journal of Applied Physiology, American Physiological Society, Vol. 106, No. 4 ( 2009-04), p. 1181-1186
Abstract:
Although both capillary density and peak oxygen consumption (V̇o 2 ) improve with exercise training, it is difficult to find a relationship between these two measures. It has been suggested that peak V̇o 2 may be more related to central hemodynamics than to the oxidative potential of skeletal muscle, which may account for this observation. We hypothesized that change in a measure of submaximal performance, anaerobic threshold, might be related to change in skeletal muscle capillary density, a marker of oxidative potential in muscle, with training. Due to baseline differences among these variables, we also hypothesized that relationships might be sex specific. A group of 21 subjects completed an inactive control period, whereas 28 subjects (17 men and 11 women) participated in a 6-mo high-intensity exercise program. All subjects were sedentary, overweight, and dyslipidemic. Potential relationships were assessed between change in capillary density with both change in V̇o 2 at peak and at anaerobic threshold with exercise training. All variables and relationships were assessed for sex-specific effects. Change in peak V̇o 2 was not related to change in capillary density after exercise training in either sex. Men had a positive correlation between change in V̇o 2 at anaerobic threshold and change in capillary density with exercise training ( r = 0.635; P 〈 0.01), whereas women had an inverse relationship ( r = −0.636; P 〈 0.05) between the change in these variables. These findings suggest that, although enhanced capillary density is associated with training-induced improvements in submaximal performance in men, this relationship is different in women.
Type of Medium:
Online Resource
ISSN:
8750-7587
,
1522-1601
DOI:
10.1152/japplphysiol.90947.2008
Language:
English
Publisher:
American Physiological Society
Publication Date:
2009
detail.hit.zdb_id:
1404365-8
SSG:
12
SSG:
31
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