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  • 1
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    Assessment of the quality and content of national and international guidelines on hypertensive disorders of pregnancy using the AGREE II instrument
    BMJ ; 2016
    In:  BMJ Open Vol. 6, No. 1 ( 2016-01), p. e009189-
    Details
    In: BMJ Open, BMJ, Vol. 6, No. 1 ( 2016-01), p. e009189-
    Type of Medium: Online Resource
    ISSN: 2044-6055 , 2044-6055
    URL: Article
    DOI: 10.1136/bmjopen-2015-009189
    Language: English
    Publisher: BMJ
    Publication Date: 2016
    detail.hit.zdb_id: 2599832-8
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  • 2
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    Weight loss and dietary improvements following the Healthy Lifestyle Change Program, a community‐based intervention for adults with developmental disabilities
    Wiley ; 2008
    In:  The FASEB Journal Vol. 22, No. S1 ( 2008-03)
    Details
    In: The FASEB Journal, Wiley, Vol. 22, No. S1 ( 2008-03)
    Type of Medium: Online Resource
    ISSN: 0892-6638 , 1530-6860
    URL: Issue
    URL: Article
    DOI: 10.1096/fsb2.v22.S1
    DOI: 10.1096/fasebj.22.1_supplement.682.7
    Language: English
    Publisher: Wiley
    Publication Date: 2008
    detail.hit.zdb_id: 1468876-1
    SSG: 12
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  • 3
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    Quality and Content Concordance of International Clinical Guidelines on Hypertensive Disorders of Pregnancy Using the AGREE II Instrument: An Updated Systematic Review
    MDPI AG ; 2023
    In:  Journal of Cardiovascular Development and Disease Vol. 10, No. 7 ( 2023-07-11), p. 295-
    Details
    In: Journal of Cardiovascular Development and Disease, MDPI AG, Vol. 10, No. 7 ( 2023-07-11), p. 295-
    Abstract: Utilization of high-quality clinical practice guidelines has the potential to positively impact health outcomes. This study aimed to assess the quality and content concordance of national and international recommendations on hypertensive disorders of pregnancy (HDPs). Searches were conducted of the MEDLINE database and reference lists generated from national and international agencies. Covidence software was used for the management of the systematic review process, the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool was used to assess guidelines for quality, and three reviewers independently screened records. The research team identified and screened a total of 399 records of which 10 were deemed high quality. Guidelines were assessed and compared regarding the treatment, prevention, and categorization of disorders. The quality of guidelines varied across different domains, with significant variation in domain scores even within individual guidelines. Not all recommendations showed a high level of methodologic rigor, and the highest-rated guidelines were from the American Heart Association, the World Health Organization, and South Africa national guidelines. Classification of hypertension differed among the guidelines, particularly in defining chronic hypertension, severe hypertension, and preeclampsia. Prevention modalities varied across guidelines, with recommendations for aspirin, calcium supplementation, and against the use of certain approaches. Treatment modalities highlighted the importance of delivery as the definitive way to terminate hypertensive disorders of pregnancy, with other management strategies provided for symptom control. The variability in guidelines and consensus statements across different contexts may reflect regional differences in healthcare practices, available resources, and research evidence. There is potential to harmonize guidelines for HDP globally while considering the unique needs of individual countries. Where guidelines may be synthesized and condensed into an accessible format, doing so could improve their use in clinical decision-making.
    Type of Medium: Online Resource
    ISSN: 2308-3425
    URL: Article
    DOI: 10.3390/jcdd10070295
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2777082-5
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  • 4
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    Qualitative Studies of Infant and Young Child Feeding in Lower-Income Countries: A Systematic Review and Synthesis of Dietary Patterns
    MDPI AG ; 2017
    In:  Nutrients Vol. 9, No. 10 ( 2017-10-18), p. 1140-
    Details
    In: Nutrients, MDPI AG, Vol. 9, No. 10 ( 2017-10-18), p. 1140-
    Type of Medium: Online Resource
    ISSN: 2072-6643
    URL: Article
    DOI: 10.3390/nu9101140
    Language: English
    Publisher: MDPI AG
    Publication Date: 2017
    detail.hit.zdb_id: 2518386-2
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  • 5
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    Protein intake and lumbar bone density: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Cambridge University Press (CUP) ; 2014
    In:  British Journal of Nutrition Vol. 112, No. 8 ( 2014-10-28), p. 1384-1392
    Details
    In: British Journal of Nutrition, Cambridge University Press (CUP), Vol. 112, No. 8 ( 2014-10-28), p. 1384-1392
    Abstract: Dietary protein has been shown to increase urinary Ca excretion in randomised controlled trials, and diets high in protein may have detrimental effects on bone health; however, studies examining the relationship between dietary protein and bone health have conflicting results. In the present study, we examined the relationship between dietary protein (total, animal and vegetable protein) and lumbar spine trabecular volumetric bone mineral density (vBMD) among participants enrolled in the Multi-Ethnic Study of Atherosclerosis ( n 1658). Protein intake was assessed using a FFQ obtained at baseline examination (2000–2). Lumbar spine vBMD was measured using quantitative computed tomography (2002–5), on average 3 years later. Multivariable linear and robust regression techniques were used to examine the associations between dietary protein and vBMD. Sex and race/ethnicity jointly modified the association of dietary protein with vBMD ( P for interaction = 0·03). Among white women, higher vegetable protein intake was associated with higher vBMD ( P for trend = 0·03), after adjustment for age, BMI, physical activity, alcohol consumption, current smoking, educational level, hormone therapy use, menopause and additional dietary factors. There were no consistently significant associations for total and animal protein intakes among white women or other sex and racial/ethnic groups. In conclusion, data from the present large, multi-ethnic, population-based study suggest that a higher level of protein intake, when substituted for fat, is not associated with poor bone health. Differences in the relationship between protein source and race/ethnicity of study populations may in part explain the inconsistent findings reported previously.
    Type of Medium: Online Resource
    ISSN: 0007-1145 , 1475-2662
    URL: Article
    DOI: 10.1017/S0007114514002220
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2014
    detail.hit.zdb_id: 2016047-1
    SSG: 12
    SSG: 21
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  • 6
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    Obesity during childhood is associated with higher cancer mortality rate during adulthood: the i3C Consortium
    Springer Science and Business Media LLC ; 2022
    In:  International Journal of Obesity Vol. 46, No. 2 ( 2022-02), p. 393-399
    Details
    In: International Journal of Obesity, Springer Science and Business Media LLC, Vol. 46, No. 2 ( 2022-02), p. 393-399
    Abstract: In high-income countries, cancer is the leading cause of death among middle-aged adults. Prospective data on the effects of childhood risk exposures on subsequent cancer mortality are scarce. Methods We examined whether childhood body mass index (BMI), blood pressure, glucose and lipid levels were associated with adult cancer mortality, using data from 21,012 children enrolled aged 3–19 years in seven prospective cohort studies from the U.S., Australia, and Finland that have followed participants from childhood into adulthood. Cancer mortality (cancer as a primary or secondary cause of death) was captured using registries. Results 354 cancer deaths occurred over the follow-up. In age-, sex, and cohort-adjusted analyses, childhood BMI (Hazard ratio [HR], 1.13; 95% confidence interval [CI] 1.03–1.24 per 1-SD increase) and childhood glucose (HR 1.22; 95%CI 1.01–1.47 per 1-SD increase), were associated with subsequent cancer mortality. In a multivariable analysis adjusted for age, sex, cohort, and childhood measures of fasting glucose, total cholesterol, triglycerides, and systolic blood pressure, childhood BMI remained as an independent predictor of subsequent cancer mortality (HR, 1.24; 95%CI, 1.03–1.49). The association of childhood BMI and subsequent cancer mortality persisted after adjustment for adulthood BMI (HR for childhood BMI, 1.35; 95%CI 1.12–1.63). Conclusions Higher childhood BMI was independently associated with increased overall cancer mortality.
    Type of Medium: Online Resource
    ISSN: 0307-0565 , 1476-5497
    URL: Article
    DOI: 10.1038/s41366-021-01000-3
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2101927-7
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  • 7
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    Abstract P451: Coronary Artery Calcium and the Association Between Dietary Fish Intake and Atherosclerotic Cardiovascular Disease Risk
    Ovid Technologies (Wolters Kluwer Health) ; 2023
    In:  Circulation Vol. 147, No. Suppl_1 ( 2023-02-28)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 147, No. Suppl_1 ( 2023-02-28)
    Abstract: Introduction: Current guidelines recommend ≥2 servings of fish/week for the prevention of atherosclerotic cardiovascular disease (ASCVD). However, a recent large meta-analysis suggested that the benefit may exist only for persons with a prior ASCVD event. Whether coronary artery calcium (CAC) can help to identify individuals who are likely to benefit from habitual fish consumption is unknown. Hypothesis: CAC will stratify persons who may and may not benefit from habitual fish consumption. Methods: There were 4977 participants in the Multi-Ethnic Study of Atherosclerosis who reported their frequency of fish intake and underwent CAC scanning at Visit 1. Adjusted Cox proportional hazards regression models stratified by the presence/absence of CAC assessed the association between fish intake and incident ASCVD over a median follow-up of 15.7 years. Results: The mean age was 61 years old, 53% were women, 26% were Black, and 49% of participants had prevalent CAC. A similar proportion of individuals reported consuming ≥2 servings of fish/week for those with CAC=0 and CAC 〉 0 (35% versus 33%, p=0.12). The absolute ASCVD event rate for those with 〈 2 or ≥2 servings of fish/week was 5.5 vs. 4.2 per 1,000 person-years for CAC=0 and 18.2 vs. 19.0 person-years for CAC 〉 0 (Figure 1). Each additional serving of fish/week was associated with a 9% lower risk of ASCVD for participants with CAC=0 (HR=0.91, 95% CI: 0.83-0.99) whereas there was no significant association for persons with CAC 〉 0 (HR=1.03, 95% CI: 0.99-1.07). Conclusions: A higher amount of fish consumption was associated with a lower risk of incident ASCVD for participants with CAC=0, but not those with CAC 〉 0, although the absolute ASCVD event rate was low for persons with CAC=0 regardless of fish consumption frequency.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/circ.147.suppl_1.P451
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2023
    detail.hit.zdb_id: 1466401-X
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  • 8
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    Abstract 10922: Relationship of the AHA Impact Goals (Life’s Simple 7) With Risk of Chronic Kidney Disease: Results From the ARIC Cohort Study
    Ovid Technologies (Wolters Kluwer Health) ; 2015
    In:  Circulation Vol. 132, No. suppl_3 ( 2015-11-10)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 132, No. suppl_3 ( 2015-11-10)
    Abstract: Introduction: As part of its 2020 Impact Goals, the AHA developed the Life’s Simple 7 metric for cardiovascular health promotion. The metric consists of ideal categories for smoking, physical activity, diet, body mass index, blood pressure, blood cholesterol, and blood glucose; and its relationship with risk of chronic kidney disease (CKD) is unknown. Hypothesis: Ideal levels of health factors and the overall Life’s Simple 7 metric are associated with lower risk of developing CKD. Methods: We prospectively analyzed 15,436 Atherosclerosis Risk in Community study participants without CKD at baseline (1987-1989). Ideal levels of health factors were: non-smoker or quit 〉 1 year ago; body mass index 〈 25 kg/m 2 ; ≥150 minutes/week of physical activity; dietary pattern which is high in fruits and vegetables, fish, and fiber-rich whole grains, and low in sodium and sugar-sweetened beverages; total cholesterol 〈 200 mg/dL; blood pressure 〈 120/90 mmHg; and blood glucose 〈 100 mg/dL. Incident CKD was defined as development of estimated glomerular filtration rate 〈 60 mL/min/1.73 m 2 accompanied by 25% decline from baseline, hospitalization or death due to CKD, or end-stage renal disease defined by linkage with the U.S. Renal Data System. Cox regression was used to estimate associations between health factors, the overall metric, and CKD risk while adjusting for age, sex, race, and baseline kidney function. Results: At baseline, mean age was 54 years, 55% were women, and 26% were African-American. There were 2,861 incident CKD cases over a median follow-up of 22 years. Smoking, body mass index, physical activity, blood pressure, and blood glucose were associated with lower CKD risk (all p≤0.01), but diet and blood cholesterol were not. CKD risk was inversely related to the number of ideal health factors ( Figure ; p-trend 〈 0.001; AUC: 0.7001 vs. 0.6804, p 〈 0.001). Conclusions: The AHA Life’s Simple 7 metric, developed to measure and promote cardiovascular health, predicts reduced CKD risk.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/circ.132.suppl_3.10922
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2015
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  • 9
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    Abstract P177: Discordantly Normal ApoB Relative To Elevated LDL-C In Persons With Metabolic Disorders: A Marker Of Atherogenic Heterogeneity
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Circulation Vol. 143, No. Suppl_1 ( 2021-05-25)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 143, No. Suppl_1 ( 2021-05-25)
    Abstract: Introduction: A significant proportion of persons with metabolic syndrome, prediabetes, or type 2 diabetes do not develop atherosclerotic cardiovascular disease (ASCVD). Discordantly normal apolipoprotein B (ApoB) relative to elevated LDL-cholesterol (LDL-C) may help to explain underlying heterogeneity in ASCVD risk among these individuals. Hypothesis: We hypothesized that discordantly normal ApoB ( 〈 90 mg/dL) relative to elevated LDL-C ( 〉 100 mg/dL) would be associated with a lower atherosclerosis burden among individuals with metabolic disorders. Methods: There were 331 Bogalusa Heart Study participants with metabolic syndrome (n=107), prediabetes (n=291), or type 2 diabetes (n=34) and LDL-C 〉 100 who were free of carotid plaque at baseline (2001-02) and underwent carotid ultrasound at follow-up (2013-16). Carotid plaque was defined as a focal wall thickening 〉 1.5 mm. Modified Poisson regression with robust error variance estimated the long-term absence of plaque for normal ApoB after adjusting for established risk factors. Results: Participants were on average 36.3 years old at baseline, 202 (61.0%) were women, and 93 (29.9%) were African American. Overall, LDL-C explained 42.3% of the variability in ApoB as the lipoprotein markers were only modestly correlated (r=0.65). Participants with ApoB 〈 90 (51.1%) were more likely to remain free of carotid plaque compared to those with ApoB 〉 90 (74.6% versus 57.4%, p=0.001, Figure ). In multivariable modeling, persons with ApoB 〈 90 were 21% more likely to have long-term absence of plaque (RR=1.21, 95% CI: 1.03-1.43), independent of traditional ASCVD risk factors, including LDL-C. Conclusions: More than half of persons with metabolic disorders and elevated LDL-C had normal ApoB with a lower burden of carotid atherosclerosis over 13 years follow-up. ApoB better represents the atherogenic lipid burden among persons with metabolic disorders compared to LDL-C and may be especially helpful for persons with the pattern of high triglycerides and low HDL-cholesterol.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/circ.143.suppl_1.P177
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
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  • 10
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    Abstract 15104: Diverse Associations Between Long-Term Body Mass Index Variability and Midlife Cognitive Function: The Bogalusa Heart Study
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Circulation Vol. 146, No. Suppl_1 ( 2022-11-08)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 146, No. Suppl_1 ( 2022-11-08)
    Abstract: Introduction: Evidence shows that individual variation of body weight over time may have a role in explaining cognitive decline later in life independent from obesity status. Yet, the effect of long-term variability from childhood on midlife cognitive function (CF), as well as race differences remains unclear. This study examines this association among Black and White middle-aged individuals from a community cohort in Bogalusa, Louisiana. Methods: A total of 1,268 participants (59.5% women, 34.4% Black) from the Bogalusa Heart Study who had 〉 4 BMI measurements from childhood (mean age: 9.5 ± 3.5), and complete neuropsychological (NP) tests assessment to evaluate CF at midlife (48.2 ± 5.2) were studied. CF was measured with a global cognitive score (GCS). Long-term BMI variability was computed as standard deviation (SD), coefficient of variation (CV), deviation from age-predicted values (DEV), and residual SD (RSD). Regression models were used to evaluate the associations between BMI variability and GCS. Covariates included age, sex, race, cardiovascular risk factors, depression, class II obesity (BMI ≥ 35kg/m 2 ) at midlife, alcohol use, education and employment status. Race, sex and BMI variability interactions were evaluated. Results: Overall, higher DEV and RSD [Beta (SE): -0.30 (0.10); p = 0.003, and – 0.17 (0.08); p = 0.025, respectively] was associated with lower GCS. Interactions between SD, CV, DEV, and RSD with race were significant, but not with sex. Stratified analyses of the relationship between BMI variability measures and GCS showed the following result among White participants [DEV Beta (SE): -0.25 (0.10); p = 0.01] and Black participants [DEV Beta (SE): -0.03 (0.13); p = 0.81], respectively. Conclusion: We identified diverse associations between BMI variability from childhood and cognitive function in midlife. Although Black participants appear more resilient to the influence of BMI variability on CF in midlife, further studies are needed to identify the nature of this complex phenomenon and its potential to contribute to vascular causes of cognitive decline and dementia.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/circ.146.suppl_1.15104
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 1466401-X
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