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  • 1
    Online Resource
    Online Resource
    Wiley ; 2007
    In:  Acta Ophthalmologica Scandinavica Vol. 85, No. s240 ( 2007-09), p. 0-0
    In: Acta Ophthalmologica Scandinavica, Wiley, Vol. 85, No. s240 ( 2007-09), p. 0-0
    Abstract: Purpose: Our purpose was to analyze the various ocular manifestations, treatment options, and the possible outcome of congenital aniridia (CA) a rare and severe developmental disorder. Methods: 52 eyes of 26 patients were regularly checked with full eye examination including anterior segment photography. Electrophysiology, OCT, UBM, and glaucoma testing was done if appropriate. The mean age at the last examination was 17.6 years (range: 2 months – 72 years). Results: The best corrected visual acuity was: 0.2 (ranging from no light perception to 0.6). 20 cases were sporadic and 6 cases showed autosomal dominant inheritance in 3 families. A deletion including band p13 of the short arm of chromosome 11 was found in one familial and one sporadic case. Associated ocular signs were nystagmus (88.5%), congenital cataract (61.5%), and ectopia lentis (3.8%). 14 eyes of 10 cases needed cataract surgery. Secondary glaucoma occurred in 24 eyes of 12 patients, with severe outcome in 15 eyes of 8 patients despite treatment. Aniridic keratopathy occurred in 23 eyes of 12 patients; in 3 cases keratoplasty was performed. One patient had aniridia on one eye, and iris coloboma on the fellow eye confirming the common origin of the two diseases. Interestingly, no Wilms tumor occurred in our series, but mental deficits were found in 4 patients. Conclusions: Secondary glaucoma is the most severe complication of CA. It can appear in relatively young age, is relatively resistant to treatment, and the earlier the onset, the worse the prognosis. Risk factors for vision loss included eye surgeries at young age. Moreover, the outcome of cataract‐surgery is limited by foveal hypoplasia and the progression of glaucoma.
    Type of Medium: Online Resource
    ISSN: 1395-3907 , 1600-0420
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 2007
    detail.hit.zdb_id: 2466981-7
    detail.hit.zdb_id: 2024571-3
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  • 2
    Online Resource
    Online Resource
    Wiley ; 2014
    In:  Acta Ophthalmologica Vol. 92, No. s253 ( 2014-09), p. 0-0
    In: Acta Ophthalmologica, Wiley, Vol. 92, No. s253 ( 2014-09), p. 0-0
    Abstract: Purpose To examine the anterior chamber flare and corneal Langerhans cells (LC)in rheumatoid arthritis (RA) and compare the results to those found in patients with dry eye disease (DED) and in age matched control (C). Methods 15 patients with RA (11 women, és 4 men, mean age: 67.3±8.6 years), 20 DED patients (11 women, 9 men, mean age: 57.2±14.4 years) and 15 control subjects (8 women, 7 men, mean age: 49.6±19.1 years) were enrolled in this study. Anterior chamber flare was evaluated using Kowa FC‐600 laser flare meter and corneal LC densities were investigated at the corneal centre with confocal microscopy (Heidelberg Retina Tomograph with Rostock Cornea Modul (HRT II RCM)) in all groups. Results There was a significant difference in the flare values between RA and DED patients (6,65 f/ms in RA and 4,75 f/ms in DED (p 〈 0.01). Central LC density was: 57.6±34.4/mm2 in RA and 52.3±31.3/mm2 in DED respectively. Both values were significantly lower than that of in control (24.6±18.6/mm2, p 〈 0.05) Conclusion The blood aqueous barrier might be altered in RA even without signs of clinically significant ocular inflammation. This alteration in the blood aqueous barrier might contribute to the accumulation of LCs at the corneal centre. The greater LC density and flare values found in RA might represent novel players in the pathogenesis of dry eye.
    Type of Medium: Online Resource
    ISSN: 1755-375X , 1755-3768
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 2466981-7
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  • 3
    In: Clinical ophthalmology, LLC Russian Medical Journal, Vol. 16, No. 3 ( 2016), p. 132-136
    Type of Medium: Online Resource
    ISSN: 2311-7729
    Uniform Title: Влияние версии программного обеспечения ОКТ на обнаружение изменений в комплексе ганглионарных клеток сетчатки при экстракции катаракты
    Language: Unknown
    Publisher: LLC Russian Medical Journal
    Publication Date: 2016
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  • 4
    Online Resource
    Online Resource
    BMJ ; 1996
    In:  British Journal of Ophthalmology Vol. 80, No. 5 ( 1996-05-01), p. 488-488
    In: British Journal of Ophthalmology, BMJ, Vol. 80, No. 5 ( 1996-05-01), p. 488-488
    Type of Medium: Online Resource
    ISSN: 0007-1161
    RVK:
    Language: English
    Publisher: BMJ
    Publication Date: 1996
    detail.hit.zdb_id: 1482974-5
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 2006
    In:  European Journal of Ophthalmology Vol. 16, No. 1 ( 2006-01), p. 24-29
    In: European Journal of Ophthalmology, SAGE Publications, Vol. 16, No. 1 ( 2006-01), p. 24-29
    Abstract: To compare changes in corneal topographic parameters after cataract surgery in eyes with different severities of arcus lipoides. Methods Fourty eyes of 40 patients (23 women, 17 men, age 71.3±20.4 years, range 40 to 89 years) were studied prospectively in a consecutive, non-interventional, comparative series of cases. Eyes were classed in three groups (0 to 2) according to the assessed grade of arcus lipoides (none, 〈 180°, 〉 180°). Corneal topography (Tomey TMS-2) was performed preoperatively and at 1 and 10 days and 1 and 3 months following cataract surgery (superior 4.0 mm clear corneal incision, no suture). Keratometric astigmatism (Dcyl), surface regularity index (SRI), surface asymmetry index (SAI), and potential visual acuity (PVA) were evaluated for the different groups and time-points, using the Kruskal-Wallis, Wilcoxon, and Mann-Whitney statistical tests. Results No significant preoperative difference was found in mean Dcyl, SRI, or PVA; preoperative SAI was lower in Group 1. Postoperatively Dcyl was increased at day 1 in Groups 1 and 2, and remained higher in Group 2 until month 1. At month 3 significant differences among Groups 0, 1, and 2 disappeared. Conclusions The 4.0 mm superior clear corneal incision is a safe method for cataract surgery in the presence of arcus lipoides. This procedure induces greater corneal astigmatism, surface irregularity, and lower PVA in the early postoperative period in cases with arcus lipoides than in normal corneas. Concerning final results, wound healing was not affected by greater severity of arcus lipoides, although stabilization of the corneal surface tended to be slower.
    Type of Medium: Online Resource
    ISSN: 1120-6721 , 1724-6016
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2006
    detail.hit.zdb_id: 1475018-1
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  • 6
    Online Resource
    Online Resource
    Akademiai Kiado Zrt. ; 2018
    In:  Developments in Health Sciences Vol. 1, No. 3 ( 2018-12), p. 78-81
    In: Developments in Health Sciences, Akademiai Kiado Zrt., Vol. 1, No. 3 ( 2018-12), p. 78-81
    Abstract: This study aimed to examine the effectiveness of CO 2 laser-assisted sclerectomy surgery (CLASS) in eyes with primary open-angle glaucoma (POAG) showing progression in spite of maximal local antiglaucomatous therapy. Materials and methods Patients with progressive POAG received CLASS treatment. We performed CLASS on 15 eyes (eight males and seven females). The primary endpoint was the change in the intraocular pressure (IOP), and additionally best spectacle-corrected visual acuity (BSCVA), C/D ratio (cup-to-disc), as well as use of antiglaucomatous drops were also investigated. Following the preoperative assessment, measurements were performed at 6-month follow-up. Results The average preoperative IOP was 26.13 ± 6.79 mmHg that dropped to 9.57 ± 4.09 mmHg at 1 day. IOP was stable at 1 month, 3 months, and 6 months. The BSCVA decreased to the 1-day and 1-week follow-up but returned to its original value to the 1-month check-up. Preoperatively, all patients were on maximal antiglaucoma drop therapy, after CLASS none of the patients needed antiglaucomatous treatment at 1 month. However, at 3 months, one of them needed antiglaucoma drops. C/D ratio showed non-significant changes. Conclusions CLASS procedure was found to be effective in decreasing IOP in POAG patients whose IOP was not compensated with maximal antiglaucomatous local therapy; patients needed significantly less local therapy following the CO 2 laser surgery.
    Type of Medium: Online Resource
    ISSN: 2630-9378 , 2630-936X
    Language: Unknown
    Publisher: Akademiai Kiado Zrt.
    Publication Date: 2018
    detail.hit.zdb_id: 3063819-7
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