In:
Journal of Magnetic Resonance Imaging, Wiley, Vol. 58, No. 2 ( 2023-08), p. 620-629
Abstract:
The T 2 w sequence is a standard component of a prostate MRI examination; however, it is time‐consuming, requiring multiple signal averages to achieve acceptable image quality. Purpose/Hypothesis To determine whether a denoised, single‐average T 2 sequence (T 2 ‐R) is noninferior to the standard multiaverage T 2 sequence (T 2 ‐S) in terms of lesion detection and PI‐RADS score assessment. Study Type Retrospective. Population A total of 45 males (age range 60–75 years) who underwent clinically indicated prostate MRI examinations, 21 of whom had pathologically proven prostate cancer. Field Strength/Sequence A 3 T; T 2 w FSE , DWI with ADC maps, and dynamic contrast‐enhanced images with color‐coded perfusion maps. T 2 ‐R images were created from the raw data utilizing a single “average” with iterative denoising. Assessment Nine readers randomly assessed complete exams including T 2 ‐R and T 2 ‐S images in separate sessions. PI‐RADS version 2.1 was used. All readers then compared the T 2 ‐R and T 2 ‐S images side by side to evaluate subjective preference. An additional detailed image quality assessment was performed by three senior level readers. Statistical Tests Generalized linear mixed effects models for differences in lesion detection, image quality features, and overall preference between T 2 ‐R and T 2 ‐S sequences. Intraclass correlation coefficients (ICC) were used to assess reader agreement for all comparisons. A significance threshold of P = 0.05 was used for all statistical tests. Results There was no significant difference between sequences regarding identification of lesions with PI‐RADS ≥3 ( P = 0.10) or PI‐RADS score ( P = 0.77). Reader agreement was excellent for lesion identification (ICC = 0.84). There was no significant overall preference between the two sequences regarding image quality ( P = 0.07, 95% CI: [−0.23, 0.01]). Reader agreement was good regarding sequence preference (ICC = 0.62). Data Conclusion Use of single‐average, denoised T 2 ‐weighted images was noninferior in prostate lesion detection or PI‐RADS scoring when compared to standard multiaverage T 2 ‐weighted images. Evidence Level 3. Technical Efficacy Stage 3.
Type of Medium:
Online Resource
ISSN:
1053-1807
,
1522-2586
Language:
English
Publisher:
Wiley
Publication Date:
2023
detail.hit.zdb_id:
1497154-9
Permalink