In:
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, The Royal Society, Vol. 374, No. 2079 ( 2016-10-28), p. 20150377-
Abstract:
The application range of electrospray ionization mass spectrometry for the quantitative determination of stoichiometries and binding constants for non-covalent protein complexes is broadly discussed. The underlying fundamental question is whether or not the original molecular equilibrium can be preserved during the ionization process and be revealed by subsequent mass spectrometry analysis. Here, we take a new look at this question by discussing recent studies in droplet chemistry. This article is part of the themed issue ‘Quantitative mass spectrometry’.
Type of Medium:
Online Resource
ISSN:
1364-503X
,
1471-2962
DOI:
10.1098/rsta.2015.0377
Language:
English
Publisher:
The Royal Society
Publication Date:
2016
detail.hit.zdb_id:
208381-4
detail.hit.zdb_id:
1462626-3
SSG:
11
SSG:
5,1
SSG:
5,21
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