In:
Natural Product Communications, SAGE Publications, Vol. 8, No. 6 ( 2013-06), p. 1934578X1300800-
Kurzfassung:
A new ent –kaurane type diterpene glucoside, pulicarside (1), together with three known terpenoids, paniculoside IV (2, diterpene), ent–16, 17-dihydroxy-(-)-kauran-19–oic acid (3, diterpene), and 2α–hydroxy alantolactone (4, sesquiterpene) have been isolated from Pulicaria undulata L. Their structures were determined with the help of spectral studies. Pulicarside (1) showed α-glucosidase activator activity, whereas its hydrolyzed product ent-16, 17-dihydroxy-(-)-kauran-19-oic acid (3) exhibited strong α-glucosidase inhibitory activity. Paniculoside IV (2) also shows high inhibitory potency compared with the standard drug acarbose.
Materialart:
Online-Ressource
ISSN:
1934-578X
,
1555-9475
DOI:
10.1177/1934578X1300800618
Sprache:
Englisch
Verlag:
SAGE Publications
Publikationsdatum:
2013
ZDB Id:
2430442-6
SSG:
15,3
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