In:
Epidemiology and Health, Korean Society of Epidemiology, Vol. 44 ( 2022-06-09), p. e2022052-
Abstract:
OBJECTIVES: Although there is substantial evidence for the short-term effect of fine particulate matter (PM 〈 sub 〉 2.5 〈 /sub 〉 ) on daily mortality, few epidemiological studies have explored the effect of prolonged continuous exposure to high concentrations of PM 〈 sub 〉 2.5 〈 /sub 〉 . This study investigated how the magnitude of the mortality effect of PM 〈 sub 〉 2.5 〈 /sub 〉 exposure is modified by persistent exposure to high PM 〈 sub 〉 2.5 〈 /sub 〉 concentrations.METHODS: We analyzed data on the daily mortality count, simulated daily PM 〈 sub 〉 2.5 〈 /sub 〉 level, mean daily temperature, and relative humidity level from 7 metropolitan cities from 2006 to 2019. Generalized additive models (GAMs) with quasi-Poisson distribution and random-effects meta-analyses were used to pool city-specific effects. To investigate the effect modification of continuous exposure to prolonged high concentrations, we applied categorical consecutive-day variables to the GAMs as effect modification terms for PM 〈 sub 〉 2.5 〈 /sub 〉 .RESULTS: The mortality risk increased by 0.33% (95% confidence interval [CI], 0.16 to 0.50), 0.47% (95% CI, -0.09 to 1.04), and 0.26% (95% CI, -0.08 to 0.60) for all-cause, respiratory, and cardiovascular diseases, respectively, with a 10 μg/m3 increase in PM 〈 sub 〉 2.5 〈 /sub 〉 concentration. The risk of all-cause mortality per 10 μg/m3 increase in PM 〈 sub 〉 2.5 〈 /sub 〉 on the first and fourth consecutive days significantly increased by 0.63% (95% CI, 0.20 to 1.06) and 0.36% (95% CI, 0.01 to 0.70), respectively.CONCLUSIONS: We found increased risks of all-cause, respiratory, and cardiovascular mortality related to daily PM 〈 sub 〉 2.5 〈 /sub 〉 exposure on the day when exposure to high PM 〈 sub 〉 2.5 〈 /sub 〉 concentrations began and when exposure persisted for more than 4 days with concentrations of ≥35 μg/m3. Persistently high PM 〈 sub 〉 2.5 〈 /sub 〉 exposure had a stronger effect on seniors.
Type of Medium:
Online Resource
ISSN:
2092-7193
DOI:
10.4178/epih.e2022052
Language:
English
Publisher:
Korean Society of Epidemiology
Publication Date:
2022
detail.hit.zdb_id:
2590698-7
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