In:
Nepalese Heart Journal, Nepal Journals Online (JOL), Vol. 3, No. 3 ( 2004-11-30), p. 75-
Abstract:
A cross-over and multiple dose study was carried out to find out possible pharmacokinetic interactions between phenytoin (DPH 35 ma/kg; p.o.) and antihypertensives enalapril (1.6 mg/kg; p.o.) and amlodipine (0.4 mg/kg, p.o.) in rhesus monkeys. Neither the plasma concentrations nor the pharmacokinetic parameters of DPH were altered by coadministration of enalapril or amlodipine, suggesting that enalapril and amlodipine can be safely administered to epileptic patients receiving phenytoin.
Type of Medium:
Online Resource
ISSN:
2382-5464
,
2091-2978
DOI:
10.3126/njh.v3i3.26143
Language:
Unknown
Publisher:
Nepal Journals Online (JOL)
Publication Date:
2004
detail.hit.zdb_id:
2901174-7
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