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  • 1
    Online Resource
    Online Resource
    Biogenic fabrication of nanomaterials from flower-based chemical compounds, characterization and their various applications: A review
    Elsevier BV ; 2020
    In:  Saudi Journal of Biological Sciences Vol. 27, No. 10 ( 2020-10), p. 2551-2562
    Details
    In: Saudi Journal of Biological Sciences, Elsevier BV, Vol. 27, No. 10 ( 2020-10), p. 2551-2562
    Type of Medium: Online Resource
    ISSN: 1319-562X
    URL: Article
    DOI: 10.1016/j.sjbs.2020.05.012
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2020
    detail.hit.zdb_id: 2515206-3
    SSG: 12
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  • 2
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    Sustainable Use of Extracts of Some Plants Growing in Ethiopia for the Formulation of Herbal Shampoo and Its Antimicrobial Evaluation
    MDPI AG ; 2023
    In:  Sustainability Vol. 15, No. 4 ( 2023-02-09), p. 3189-
    Details
    In: Sustainability, MDPI AG, Vol. 15, No. 4 ( 2023-02-09), p. 3189-
    Abstract: Shampoo prepares surfactants to remove dirt, surface grease, and skin debris from hair, shaft, and scalp without harming the user. This study aimed to formulate herbal shampoo using Ethiopian plant extracts and evaluate their quality parameters. Herbal shampoos were formulated using seed oil extracts of Lepidium sativum L. and Ricinus communis L., and essential oil extracts of Lippia adeonsis Hochst ex. Walp koseret, along with other ingredients. The formulated herbal shampoos were evaluated for their organoleptic and physicochemical properties such as pH, surface tension, viscosity, dirt dispersion, antimicrobial activities, and stability. When the investigation data were assessed, the formulations were pleasant and attractive, produced sufficient foam, and showed suitable cleansing activities. The pH values were in a range 5.90 ± 0.22–7.45 ± 0.19, and lower surface tension (23.39 ± 0.20–31.89 ± 1.04 dyne/cm) together with acceptable viscosity with good shearing properties were obtained. The formulated products exhibited good antimicrobial activities against Escherichia coli, Staphylococcus aureus, and Aspergillus niger. When the surface morphologies of hair samples were examined using a scanning electron microscope (SEM), a clean and smooth surface was observed for treated samples, comparable to that of the marketed shampoo. This result indicated that the formulated herbal shampoo is good, having acceptable properties at par with commercially available shampoos. However, further investigation, research, and development are required to improve its quality and safety.
    Type of Medium: Online Resource
    ISSN: 2071-1050
    URL: Article
    DOI: 10.3390/su15043189
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2518383-7
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  • 3
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    Online Resource
    Optimization, Characterization, and Biological Applications of Silver Nanoparticles Synthesized Using Essential Oil of Aerial Part of Laggera tomentosa
    MDPI AG ; 2023
    In:  Sustainability Vol. 15, No. 1 ( 2023-01-01), p. 797-
    Details
    In: Sustainability, MDPI AG, Vol. 15, No. 1 ( 2023-01-01), p. 797-
    Abstract: Biological synthesis of silver nanoparticles (AgNPs) is a green, simple, cost-effective, time-efficient, and single-step method. This study mainly focused on the synthesis of silver nanoparticles (AgNPs) using essential oil of Laggera tomentosa (LTEO) and investigates their potential applications. Ultraviolet-Visible (UV-Vis) result showed the characteristic Surface Plasmon Resonance (SPR) peak of LTEO-AgNPs at 420 nm. Fourier transform infrared (FT-IR) spectroscopy indicated the functional groups present in LTEO and LTEO-AgNPs. Scanning electron microscope (SEM) image depicted the synthesized AgNPs mainly has spherical shapes with average nanoparticles size 89.59 ± 5.14 nm. Energy dispersive X-ray (EDX) peak at 3.0 keV showed the presence of Ag element in LTEO-AgNPs. The X-ray diffraction (XRD) peaks at 38°, 44° and 67° are assigned to (111), (200), and (220), respectively which displays the crystal nature of LTEO-AgNPs. The average particle size and zeta potential of LTEO-AgNPs were determined as 94.98 nm and −49.6 mV, respectively. LTEO-AgNPs were stable for six months against aggregation at room temperature. LTEO-AgNPs solutions exhibited potential activities for the treatment of some pathogenic bacteria species, agricultural productivity growth, determination of metallic ions, and catalytic reduction. This study is the first work to report nanoparticles synthesis using L. tomentosa extracts and evaluate their potential applications.
    Type of Medium: Online Resource
    ISSN: 2071-1050
    URL: Article
    DOI: 10.3390/su15010797
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2518383-7
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  • 4
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    Online Resource
    Green Synthesis of Gold and Silver Nanoparticles Using Invasive Alien Plant Parthenium hysterophorus and Their Antimicrobial and Antioxidant Activities
    MDPI AG ; 2023
    In:  Sustainability Vol. 15, No. 12 ( 2023-06-12), p. 9456-
    Details
    In: Sustainability, MDPI AG, Vol. 15, No. 12 ( 2023-06-12), p. 9456-
    Abstract: Due to the high energy demands and environmental hazards of physical and chemical methods, it is now essential to produce nanoparticles using plant sources as reducing and stabilizing agents. In this study, silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) were biosynthesized using an aqueous extract of Parthenium hysterophorus aerials as a reducing and stabilizing agent. The synthesized nanoparticles were characterized using UV–Vis spectroscopy, X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, dynamic light scattering (DLS), and transmission electron Microscopy (TEM). UV–Vis spectroscopy indicates that the peaks of AgNPs and AuNPs are at 422 and 538 nm, respectively. The results of the DLS analysis showed that both Au and AgNPs are monodispersed and stable and have mean hydrodynamic sizes of 53.55 nm and 68.12 nm, respectively. According to an XRD analysis, the generated AgNPs and AuNPs are face-centered cubic crystals with average crystalline diameters of 33.4 nm and 30.5 nm, respectively. TEM image depicted that the synthesized NPs mainly have spherical shapes with particle size in the range of 3.41–14.5 nm for AuNPs and 5.57–26.3 nm for AgNPs. These biologically produced AuNPs and AgNPs were investigated for their antibacterial, antifungal, and antioxidant effects. Both AuNPs and AgNPs were found to strongly influence the growth of bacterial pathogens, with a maximum zone of 22.3 and 19.7 mm in Escherichia coli and a minimum zone of 11.7 and 10.3 mm in Salmonella enterica, respectively. The synthesized AuNPs and AgNPs reduce the numbers of viable fungi by 51.06% and 47.87%, respectively. The DPPH (2,2-diphenyl-1-picrylhydrazyl) assay revealed that the synthesized AuNPs and AgNPs have significant radical scavenging ability with 88.75% and 86.25% inhibition and 33.62 μg/mL and 42.86 μg/mL of IC50, respectively. Therefore, an aqueous extract of aerial parts of P. hysterophorus can be a suitable precursor for synthesizing AuNPs and AgNPs, with numerous applications. Due to their smaller size, AuNPs have better antimicrobial and antioxidant activities than AgNPs. This study supports the conservation by a utilization strategy of invasive alien plant species control and management (such as P. hysterophorus) for biodiversity conservation and environmental sustainability.
    Type of Medium: Online Resource
    ISSN: 2071-1050
    URL: Article
    DOI: 10.3390/su15129456
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2518383-7
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  • 5
    Online Resource
    Online Resource
    Phytochemistry, pharmacological activities, nanoparticle fabrication, commercial products and waste utilization of Carica papaya L.: A comprehensive review
    Elsevier BV ; 2020
    In:  Current Research in Biotechnology Vol. 2 ( 2020-11), p. 145-160
    Details
    In: Current Research in Biotechnology, Elsevier BV, Vol. 2 ( 2020-11), p. 145-160
    Type of Medium: Online Resource
    ISSN: 2590-2628
    URL: Article
    DOI: 10.1016/j.crbiot.2020.11.001
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2020
    detail.hit.zdb_id: 3003132-1
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  • 6
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    Traditional and Phytochemical Bases of Herbs, Shrubs, Climbers, and Trees from Ethiopia for Their Anticancer Response
    Hindawi Limited ; 2022
    In:  BioMed Research International Vol. 2022 ( 2022-2-3), p. 1-27
    Details
    In: BioMed Research International, Hindawi Limited, Vol. 2022 ( 2022-2-3), p. 1-27
    Abstract: Ethiopia is one of Africa’s six plant-rich countries, with around 60% of the plants being indigenous and most of them having medicinal properties. 80% of people in the country use these plants as a primary health care system to tackle different diseases, including cancer. This review is aimed at summarizing the evidence gained from diverse MPs in Ethiopia that have been used ethnobotanically and ethnopharmacologically for treatment of cancer. The primary data sources were Google Scholar, Web of Science, Science Direct, Scopus, PubMed, and other electronic scientific databases. This literature review showed that there are around 200 MPs used as anticancer. Seventy-four herbs, 39 trees, 77 shrubs, and 17 weed/climbers belonging to 56 families have been identified for their ethnobotanical anticancer potential, and 31 species were recognized for their pharmaceutically anticancer activities. The reviewed data also indicated that many Ethiopian MPs had been used to treat breast, lung, blood, and skin cancers and other tumors. Besides, the collected data showed that the leaves (36.76%), roots (27.2%), bark (12.5%), stem (5.1%), and fruit (7.35%) of plants are commonly used for the preparation of anticancer remedies. Among the reported plant species, Euphorbiaceae (10.71%), Acanthaceae (7.14%), and Asteraceae (7.1%) are the most prominent plant families being used to treat cancer ethnobotanically. Phytochemicals such as flavonoids (like xanthone, indirubin, flavopiridol, and silybin), alkaloids (like taxol, vincristine, evodiamine, and berberine), and physalin B, D, and F steroids exhibited anticancer activity on various cancer cell lines. The crude extracts of Aerva javanica, Vernonia leopoldi, Withania somnifera, Kniphofia foliosa, and Catharanthus roseus were powerful anticancer agents with an IC50 value below 10 μg/mL. Although several Ethiopian plants possess anticancer potential, only a limited number of plants are scientifically studied. Therefore, more scientific studies on anticancer MPs should be carried out; it may lead to discovering and isolating cost-effective and safe anticancer drugs.
    Type of Medium: Online Resource
    ISSN: 2314-6141 , 2314-6133
    URL: Article
    DOI: 10.1155/2022/1589877
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2698540-8
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  • 7
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    Online Resource
    Sustainable Bioconversion of Wetland Plant Biomass for Pleurotus ostreatus var. florida Cultivation: Studies on Proximate and Biochemical Characterization
    MDPI AG ; 2022
    In:  Agriculture Vol. 12, No. 12 ( 2022-12-07), p. 2095-
    Details
    In: Agriculture, MDPI AG, Vol. 12, No. 12 ( 2022-12-07), p. 2095-
    Abstract: The abundant biomass growth of aquatic macrophytes in wetlands is one of the major concerns affecting their residing biota. Moreover, the biomass degenerates within the wetlands, thereby causing a remixing of nutrients and emission of greenhouse gases. Therefore, it is crucial to find sustainable methods to utilize the biomass of aquatic macrophytes devoid of environmental concerns. The present study investigates the utilization of the biomass of three aquatic macrophytes, including the lake sedge (CL: Carex lacustris Willd.), water hyacinth (EC: Eichhornia crassipes Mart. Solms), and sacred lotus (NL: Nelumbo nucifera Gaertn.) to produce oyster (Pleurotus ostreatus var. florida) mushrooms. For this purpose, different combinations of wheat straw (WS: as control) and macrophyte’s biomass (WH) such as control (100% WH), CL50 (50% WH + 50% CL), CL100 (100% CL), EC50 (50% WH + 50% EC), EC100 (100% EC), NL50 (50% WH + 50% NL), and NL100 (100% NL) were used for P. florida cultivation under controlled laboratory conditions. The results showed that all selected combinations of wheat straw and macrophyte biomass supported the spawning and growth of P. florida. In particular, the maximum significant (p 〈 0.05) growth, yield, bioefficiency, proximate, and biochemical parameters were reported using the WH substrate followed by CL, NL, and EC biomass, which corresponds to the reduction efficiency of the substrate parameters. Therefore, the findings of this study reveal that the biomass of selected aquatic macrophytes can be effectively utilized for sustainable mushroom cultivation while minimizing the risk associated with their self-degeneration.
    Type of Medium: Online Resource
    ISSN: 2077-0472
    URL: Article
    DOI: 10.3390/agriculture12122095
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2651678-0
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  • 8
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    Online Resource
    Targeted HPTLC Profile, Quantification of Flavonoids and Phenolic Acids, and Antimicrobial Activity of Dodonaea angustifolia (L.f.) Leaves and Flowers
    MDPI AG ; 2023
    In:  Molecules Vol. 28, No. 6 ( 2023-03-22), p. 2870-
    Details
    In: Molecules, MDPI AG, Vol. 28, No. 6 ( 2023-03-22), p. 2870-
    Abstract: In East Africa, Dodonaea angustifolia (L.f.) is a well-known medicinal herb. Its leaf is primarily studied in light of its ethnobotanical use. In terms of phytochemistry and biological activity, its flower is not studied. In a prior study, our team looked into phytochemical screening, antioxidant activity, and total phenolic levels. This study aims to compare the profiles and biological activities of the leaf and flower samples of D. angustifolia and to present therapeutic alternatives. The leaf and flower sample powders were extracted with methanol using ultrasound-assisted extraction (UAE). HPTLC profile was obtained using CAMAG—HPTLC equipped with VisionCATS software. Antimicrobial agar well diffusion assay and minimum inhibition concentration (MIC) were determined. The leaf and flower extracts of D. angustifolia showed antibacterial activity with a MIC value of 20 µg/mL against Enterococcus faecalis and Listeria monocytogenes. Similarly, 40 µg/mL was found to be effective against Aspergillus flavus. D. angustifolia flower is a rich source of flavonoids and phenolic acids. Because of its antibacterial properties and profile, which are almost the same, the flower is emerging as a viable option for medicinal alternatives.
    Type of Medium: Online Resource
    ISSN: 1420-3049
    URL: Article
    DOI: 10.3390/molecules28062870
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2008644-1
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  • 9
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    Dehydrocostus lactone from the root of Ajuga integrifolia (Buch.-Ham. Ex D. Don): Quantitative determination and in- silico study for anti-breast cancer activity
    Horizon E-Publishing Group ; 2023
    In:  Plant Science Today ( 2023-10-01)
    Details
    In: Plant Science Today, Horizon E-Publishing Group, ( 2023-10-01)
    Abstract: Many biological activities were reported for the Ajuga species, specifically for Ajuga integrifolia and its synonyms. These include antioxidant, anti-inflammatory, antidiabetic, antibacterial, blood purifier effects, and anticancer activity. This study quantitatively determines dehydrocostus lactone (DHCL) from the root of Ajuga integrifolia and its in silico study for anti-breast cancer activity. Camag HPTLC was used for TLC – densitometric estimation of dehydrocostus lactone. Estrogen receptor alpha (ER?) protein (PDB ID: 3ERT) was selected for its involvement in cell proliferation within the breast cancer cell. Tamoxifen is a reference drug commonly used in hormonal therapy, and DHCL was used as a ligand. Molecular docking was performed using AutoDock Vina in PyRx v.0.8 to get the bestconformational pose for forming the expected receptor-ligand complex. The docking result visualization was performed using LigPlot v.1.4.5 software for 2D, and the interactive visualization in 3D was done using Biovia Discovery Studio software. The presence of DHCL in the root of A. integrifolia was not reported so far. DHCL content in the root of A. integrifolia was estimated to be 16.5 ± 0.25 mg/g of crude extract using the TLC- densitometric method. From the molecular docking study, DHCL was found to be a promising inhibitor for estrogen receptor interaction in the breast cell and can be selected for further in vivo research to develop an anti-breast cancer drug.
    Type of Medium: Online Resource
    ISSN: 2348-1900
    URL: Issue
    URL: Article
    DOI: 10.14719/pst...
    DOI: 10.14719/pst.2344
    Language: Unknown
    Publisher: Horizon E-Publishing Group
    Publication Date: 2023
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  • 10
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    Online Resource
    Plants and Plant-Derived Molecules as Natural Immunomodulators
    Hindawi Limited ; 2023
    In:  BioMed Research International Vol. 2023 ( 2023-6-5), p. 1-14
    Details
    In: BioMed Research International, Hindawi Limited, Vol. 2023 ( 2023-6-5), p. 1-14
    Abstract: Background. Nowadays, the immunomodulatory properties of plants have been studied extensively with greater interest due to increasing awareness and combating the severity of immunomodulatory diseases. Scope and Approach. This paper highlights the efficacy of the available literature evidence on natural immunomodulators of plant origin and synthetic ones. In addition, several aspects of plants and their phytoconstituents responsible for immunomodulation have been discussed. Moreover, this review also discusses the mechanism involved in immunomodulation. Key Findings. One hundred fifty medicinal immunomodulatory plants are currently identified to find novel immunomodulatory drugs. Of these plants, the plant family Asteraceae also takes the first rank by offering 18 plant species (12%). Similarly of the plants studied so far, 40% belong to the Asteraceae family. Echinacea purpurea of this family is most known for its immunostimulating activity. The most prominent immune-active bioactive molecules are polyphenols, terpenoids, and alkaloids. Also, eight plant bioactive immunomodulators were checked for clinical trials and found in the market. These are six immunosuppressants, resveratrol, epigallocatechin-3-gallate, quercetin, colchicine, capsaicin, and andrographolide, and two immunostimulants, curcumin and genistein. Nowadays, there are a lot of polyherbal traditional medicinal products sold in the market and claimed to their immunomodulators. However, much work is still needed to find more active immunomodulatory agents. The mechanism by which immunomodulatory medicinal plant exert their effect is through the induction of cytokines and phagocyte cells and the inhibition of iNOS, PGE, and COX-2 synthesis.
    Type of Medium: Online Resource
    ISSN: 2314-6141 , 2314-6133
    URL: Article
    DOI: 10.1155/2023/7711297
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2023
    detail.hit.zdb_id: 2698540-8
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