In:
Public Health Nutrition, Cambridge University Press (CUP), Vol. 10, No. 8 ( 2007-08), p. 799-802
Abstract:
To assess the prevalence of hyperthyroidism just after implementation of iodine prophylaxis among adults from an area with iodine deficiency. Study design and subjects A total of 1648 adults (age 16 years and older) were sampled from an area of southern Poland during two nationwide epidemiological surveys. Of these, 1424 adults with negative medical history for thyroid disorders qualified for final analysis. The authors compared thyroid dysfunction in participants prior to (1989–1990) and after implementation of iodine prophylaxis (1997–1999). Setting The southern part of Poland. Results We found an increase in the serum concentration of anti-thyroid microsomal antibodies from 4.9% in the years 1989–1990 to 12.1% after introduction of iodised household salt ( P 〈 0.0001). The prevalence of hyperthyroidism (defined as thyroid-stimulating hormone 〈 0.4 μU ml − 1 ) significantly increased in the equivalent period from 4.8 to 6.5% ( P = 0.009). Conclusions We concluded that a sudden rise in iodine intake after implementation of iodine prophylaxis among adults from the area with iodine deficiency may lead to an increase in thyroid autoimmunity and prevalence of hyperthyroidism. Those possible early side-effects appear to be only temporary and are acceptable when compared with the evident benefits of adequate iodine intake.
Type of Medium:
Online Resource
ISSN:
1368-9800
,
1475-2727
DOI:
10.1017/S1368980007585939
Language:
English
Publisher:
Cambridge University Press (CUP)
Publication Date:
2007
detail.hit.zdb_id:
2016337-X
SSG:
21
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