In:
Bioinformatics, Oxford University Press (OUP), Vol. 22, No. 20 ( 2006-10-15), p. 2455-2458
Abstract:
In this report, we describe a novel tandem peptide repeat protein, Eicosapentapeptide repeat (EPR), which occurs notably only in flowering plants. The EPRs are characterized by a 25 amino acid repeat unit, X2CX4CX10CX2HGGG, repeated 10 times tandemly. Sequence search revealed that the repeat motif is highly conserved across its occurrence. EPRs are predicted to exist as quasi-globular stable structures owing to highly conserved amino acid positions and potential disulfide bridges. Proteins containing EPRs are predicted to be located in chloroplasts; non-enzymatic and peptide or DNA-binding in molecular function; and they are possibly involved in transcription regulation. Contact: jnagaraju@cdfd.org.in Supplementary information: Architecture, identifiers and annotations of EPRs; search parameters, distribution and sequence alignment; 2D structure prediction and disulfide connectivity are provided as pdf files S1–S8, at Bioinformatics online.
Type of Medium:
Online Resource
ISSN:
1367-4811
,
1367-4803
DOI:
10.1093/bioinformatics/btl340
Language:
English
Publisher:
Oxford University Press (OUP)
Publication Date:
2006
detail.hit.zdb_id:
1468345-3
SSG:
12
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