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  • 1
    In: Bangladesh Journal of Neuroscience, Bangladesh Academy of Sciences, Vol. 28, No. 2 ( 2013-11-30), p. 81-87
    Abstract: Background and objectives: Migraine is now ranked as number 19 among all diseases causing disability by WHO1 which is characterized by recurrent attacks of various combinations of headache and neurological, gastrointestinal and autonomic symptoms2 accompanied by photophobia, phonophobia and vomiting3. The treatment of migraine involves acute, preventive drugs and non-pharmacological strategies. The basic principle in management of migraine is avoiding the trigger factors, blocking the mediators and splinting the end organ4. Though there is no significant curable treatment but there are some internationally proven and well accepted prophylactic medication which reduces headache severity, frequency, duration and risk for rebound5. Sodium valproate and pizotifen are commonest of them6, where sodium valproate is more effective than pizotifen in the prophylaxis of migraine patients. Methods: This study was a single blind randomized clinical trial carried out in the neurology outpatient department of Bangabandhu Sheikh Mujib Medical University, Dhaka (BSMMU) for the period of 2 years, among adult patients between the age of 16-50 years. Results: A total of 120 patients were included & divided into two groups such as group-A(60 patients) treated by sodium valproate & group-B(60 patients) treated by pizotifen for a period of 6 months and followed up every two months for 3 times and showed sodium valproate is more effective than pizotifen. Conclusion: This study permit to conclude that efficacy of sodium valproate is more than pizotifen in the prophylaxis of migraine patients. DOI: http://dx.doi.org/10.3329/bjn.v28i2.17174 Bangladesh Journal of Neuroscience 2012; Vol. 28 (2): 81-87
    Type of Medium: Online Resource
    ISSN: 2408-8382 , 1023-4853
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2013
    detail.hit.zdb_id: 2573887-2
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  • 2
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 1970
    In:  TAJ: Journal of Teachers Association Vol. 20, No. 2 ( 1970-01-01), p. 116-121
    In: TAJ: Journal of Teachers Association, Bangladesh Academy of Sciences, Vol. 20, No. 2 ( 1970-01-01), p. 116-121
    Abstract: Parkinson's disease is a common disease of old age, whose major symptoms are of motor nature. Apart from the symptoms related to motor activity, patients of PD also experience various other fluctuating symptoms of a non-motor nature. These non-motor fluctuations (NMF) have been classified according to their characteristics into three categories; dysautonomic, mental (cognitive / psychiatric), and sensory / pain. These non-motor fluctuations may have a varied presentation and unless recognized by the physicians to be a feature of PD itself, lead to unnecessary and often costly or harmful investigations. The varied presentations of the non-motor fluctuations in patients of PD are presented in this study. 128 patients of PD from the Movement Disorder Clinic of the Neurology Out Patient Department of BSMMU were included in this study. 106 had motor fluctuations and 111 had non-motor fluctuations. The non-motor fluctuations were classified into sensory in 67 (63.2%) patients, autonomic in 78 (73.6%) patients and psychiatric in 18 (17%) patients. The most frequent sensory fluctuations were akathisia, pain and tingling sensations. Excessive sweating, drooling, oral dryness and flushing were the common autonomic fluctuations while depression and fatigue were the common psychiatric complaints. Most of the non-motor fluctuations were associated with motor fluctuations and with the "off" state. doi: 10.3329/taj.v20i2.3071 TAJ 2007; 20(2): 116-121
    Type of Medium: Online Resource
    ISSN: 2408-8854 , 1019-8555
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 1970
    detail.hit.zdb_id: 2754944-6
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  • 3
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2013
    In:  Bangladesh Journal of Neuroscience Vol. 28, No. 2 ( 2013-11-30), p. 132-140
    In: Bangladesh Journal of Neuroscience, Bangladesh Academy of Sciences, Vol. 28, No. 2 ( 2013-11-30), p. 132-140
    Abstract: A 40 years old man presented with progressive weakness and distal paraesthesia of limbs with difficulty in walking for last seven years. As the patient was not investigated thoroughly, a diagnostic dilemma was persisted. This patient went abroad & investigated thoroughly and yet not reached to a confirm diagnosis. Subsequently this patient reported to us and diagnosed it to be a case of Idiopathic Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) responded to oral steroid therapy. After follow-up, this patient showed marked improvement. So diagnostic dilemma that persisted with such a patient that showed improvement with treatment and a challenge to a treatable condition had encouraged us to report the case. DOI: http://dx.doi.org/10.3329/bjn.v28i2.17185 Bangladesh Journal of Neuroscience 2012; Vol. 28 (2): 132-140
    Type of Medium: Online Resource
    ISSN: 2408-8382 , 1023-4853
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2013
    detail.hit.zdb_id: 2573887-2
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  • 4
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2014
    In:  Bangladesh Journal of Neuroscience Vol. 30, No. 2 ( 2014-07-31), p. 96-103
    In: Bangladesh Journal of Neuroscience, Bangladesh Academy of Sciences, Vol. 30, No. 2 ( 2014-07-31), p. 96-103
    Abstract: Objective: To find out the relationship of different lipids, lipoproteins and ischemic stroke patients in Bangladesh. Methodology: This case control study was conducted among the patients having ischemic stroke who were admitted in Department of Neurology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh during the period from July, 1997 to June, 1999 and age, sex matched apparently healthy volunteers. Sixty ischemic stroke patients confirmed by CT scan of brain and sixty age and sex matched apparently healthy volunteers were enrolled as controls. 12 hours fasting lipid profile (Total cholesterol, LDL-cholesterol, HDLcholesterol and Triglyceride) was done for both ischemic stroke patients and healthy volunteers for comparison. The students (unpaired) t test was used to compare group means for lipids and lipoproteins. Chi square test, odds ratio with confidence interval were done to evaluate differences between the groups for other variables. P 〈 0.05 was considered as minimum level of significance. Result: The mean age (±SD) of the patients and controls were 58.45±10.12 and 59.40±10.41 years respectively and 44 (73.3%) were male and 16 (26.7%) were female and male- female ratio was 2.75:1 in both cases and controls. Total cholesterol (Means) was 201.62±5.52 mg/dl and 169.13±3.49 mg/dl in cases and controls respectively (P 〈 0.001). HDL cholesterol (Means) was 38.36±0.81 mg/dl and 44.03±0.84 mg/dl in cases and controls respectively (P 〈 0.001). LDL cholesterol (Mean±SE) in ischemic stroke patients and controls were 125.45±4.63 mg/dl and 96.40±3.23 mg/dl respectively (P 〈 0.001). Triglyceride (Mean±SE) in cases and controls were 188.50±9.35 mg/dl and 142.85±4.72 mg/dl respectively (P 〈 0.001). Conclusion: This case-control study showed significant differences of serum lipids and lipoproteins (Total cholesterol, HDL cholesterol, LDL cholesterol and triglyceride) in ischemic stroke patients than the controls in our community. Bangladesh Journal of Neuroscience 2014; Vol. 30 (2): 96-103
    Type of Medium: Online Resource
    ISSN: 2408-8382 , 1023-4853
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2014
    detail.hit.zdb_id: 2573887-2
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  • 5
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2013
    In:  Bangladesh Journal of Neuroscience Vol. 28, No. 1 ( 2013-12-01), p. 52-58
    In: Bangladesh Journal of Neuroscience, Bangladesh Academy of Sciences, Vol. 28, No. 1 ( 2013-12-01), p. 52-58
    Abstract: Bangladesh Journal of Neuroscience 2012; Vol. 28 (1): 52-58
    Type of Medium: Online Resource
    ISSN: 2408-8382 , 1023-4853
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2013
    detail.hit.zdb_id: 2573887-2
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  • 6
    In: Bangladesh Medical Journal, Bangladesh Academy of Sciences, Vol. 43, No. 2 ( 2014-12-30), p. 67-71
    Abstract: Digital subtraction angiography (DSA) is the gold standard investigation to assess the extracranial stenosis of carotid vessels. But this is an invasive diagnostic tool. So it is still a controversial issue whether duplex ultrasound is an alternative to DSA for measurement of stenosis of carotid vessels. This prospective crossectional observational study was conducted in the department of Neurology, BSMMU, Dhaka from May 2012 to April 2013 to assess the diagnostic accuracy of duplex ultrasound and its potential to replace DSA before performing carotid endarterectomy (CEA) and carotid stenting. Total of 38 patients, 33 patients of nondisabling ischaemic stroke and 5 patients with history of TIAs whose extracranial carotid stenosis was 〉 50% on duplex ultrasound were selected for DSA. DSA was done on these vessels and stenosis was measured using NASCET criteria. Results of USD and DSA were compared to determine the sensitivity, specificity and accuracy of duplex ultrasound (USD). At 70% stenosis of right internal carotid artery and left internal carotid artery the sensitivity, specificity and accuracy were 93.8%, 63.7%, 89.5% and 93.3%, 75%, 89.5% respectively. This level of diagnostic efficiency of USD is less than that of DSA of carotid arteries. It was found in this study that, USD underestimates or overestimates the degree of carotid stenosis. DSA was safe and effective in determining stenosis in this study & there was no 67 complication. So before taking any decision for carotid endarterectomy or carotid artery stenting, digital subtraction angiography of carotid vessels should be done. DOI: http://dx.doi.org/10.3329/bmj.v43i2.21385 Bangladesh Med J. 2014 May; 43 (2): 67-71
    Type of Medium: Online Resource
    ISSN: 2219-1607 , 0301-035X
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2014
    detail.hit.zdb_id: 2549257-3
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  • 7
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2013
    In:  Journal of Dhaka Medical College Vol. 21, No. 1 ( 2013-01-08), p. 3-7
    In: Journal of Dhaka Medical College, Bangladesh Academy of Sciences, Vol. 21, No. 1 ( 2013-01-08), p. 3-7
    Abstract: DOI: http://dx.doi.org/10.3329/jdmc.v21i1.13230 J. Dhaka Med. Coll. 2012; 21(1): 3-7
    Type of Medium: Online Resource
    ISSN: 2219-7494 , 1028-0928
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2013
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