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  • 1
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    Study on Seasonal Variation of Acute Myocardial Infarction Hospitalization
    Bangladesh Academy of Sciences ; 2020
    In:  Cardiovascular Journal Vol. 12, No. 2 ( 2020-07-03), p. 126-134
    Details
    In: Cardiovascular Journal, Bangladesh Academy of Sciences, Vol. 12, No. 2 ( 2020-07-03), p. 126-134
    Abstract: Background: Coronary artery disease is an important medical and public health issue as it is common and leading cause of mortality and morbidity in Bangladesh as it is throughout the world. This study was carried out to determine the existence of seasonal rhythms in hospital admissions due to acute myocardial infarction (AMI) in Dhaka Medical College Hospital. Methods: This cross-sectional observational study was conducted during the period of April 2015 to March 2016 among the patients with AMI admitted at the Cardiology Department of DMCH. 882 patients were enrolled. Results: The highest number of patients were admitted during winter (n=285, 32.3%) followed by post monsoon (n=213, 24.1%) and monsoon (n=194, 22.0%). The lowest number of patients were admitted during summer (n=190, 21.5%). The hospital admission was significantly higher in winter compared to other seasons (p-value versus summer, monsoon and post monsoon was 0.008, 0.011 and 0.042 respectively). Conclusion: A seasonal variation in the hospital admission due to AMI with a peak in winter was clearly demonstrated in the study. Persons admitted to hospital with AMI tend to be all age groups and both sexes present a stronger seasonal variation peak admission in winter. Cardiovasc. j. 2020; 12(2): 126-134
    Type of Medium: Online Resource
    ISSN: 2309-6357 , 2071-0917
    URL: Article
    DOI: 10.3329/cardio.v12i2.47990
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2020
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  • 2
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    Association of Albumin to Creatinine Ratio with Severity of Coronary Artery Disease
    Bangladesh Academy of Sciences ; 2015
    In:  University Heart Journal Vol. 10, No. 1 ( 2015-08-20), p. 18-22
    Details
    In: University Heart Journal, Bangladesh Academy of Sciences, Vol. 10, No. 1 ( 2015-08-20), p. 18-22
    Abstract: Coronary artery disease (CAD) is the most common cause of mortality and morbidity all over the world. It is also becoming a significant burden on healthcare service in Bangladesh. Atherosclerosis is the main pathology behind coronary artery disease. Endothelial dysfunction plays a crucial role in the process of atherosclerosis. Microalbuminuria (MA) is a reliable marker of endothelial dysfunction. This is why microalbuminuria is recognized as a simple marker of atherogenic milieu It was a cross sectional analytical study carried out in the department of Cardiology, Dhaka Medical College Hospital, Dhaka during the period of May, 2013 to April, 2014. After ethical consideration a total of 120 patients with IHD admitted in the department of Cardiology who fulfilled the inclusion and exclusion criteria and underwent coronary angiogram were taken as sampling population by purposive sampling. 1st morning spot urine sample was taken for measurement of ACR.Microalbumnuria was measured by rate nephelometry using Behring protein analyzer. All the study subjects were placed into two groups according to ACR value (group I- positive urinary ACR 〉 30 mg/g & group II-Normal urinary ACR 〈 30 mg/g). Angiographic severity of coronary artery disease was assessed by vessel score and stenosis score. Age and sex distribution of the subjects in two groups with MA and without MA were similar. No significant difference was observed between two groups with regard to smoking, dyslipidaemia, hypertension and family history of IHD. Prevalence of diabetes mellitus was significantly more in subjects with MA than without MA (60% vs 33.9%, p=0.006). All 40 patients of group I had significant CAD. 57(71.2%) patients of group II had significant CAD and 23(28.8%) patients had no significant CAD. The difference was highly significant (p 〈 0.001). Single vessel involvement was significantly more frequent in subjects of group II than group I (35.0% vs15.0%, p=0.022) Double vessel involvement was more in group I than group II, but the difference was not statistically significant (36.8% vs 32.40%,p=0.641).Triple vessel involvement was significantly more frequent in subjects of group I than group II (50.0% vs10.7%, p 〈 0.001). The mean stenosis score of group I was significantly higher than group II (95% CI 4.966 to 2.809, p 〈 0.001). The mean ±SD total coronary vessel score of group I was 16.60±4.75 with a range of 7.0-21.0 and mean ±SD total coronary vessel score of group II was 8.26±6.24 with a range of 0.0-21.0. The mean total score of group I wassignificantly higher than group II (95% CI 10.558 to 6.117, p 〈 0.001). Patient with microalbuminuria has more extensive and complex angiographic coronary artery disease compared to those without microalbuminuria.University Heart Journal Vol. 10, No. 1, January 2014; 18-22
    Type of Medium: Online Resource
    ISSN: 1998-927X , 1998-9261
    URL: Article
    DOI: 10.3329/uhj.v10i1.24591
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2015
    detail.hit.zdb_id: 2493547-5
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  • 3
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    Association of Serum Ferritin Level with Acute Coronary Syndrome
    Bangladesh Academy of Sciences ; 2018
    In:  Bangladesh Heart Journal Vol. 32, No. 2 ( 2018-04-10), p. 89-93
    Details
    In: Bangladesh Heart Journal, Bangladesh Academy of Sciences, Vol. 32, No. 2 ( 2018-04-10), p. 89-93
    Abstract: Background: A substantial number of patients get admitted in different hospitals of Bangladesh with the diagnosis of acute coronary syndrome (ACS). No underlying conventional risk factors can be identified in significant number of these patients. Therefore new emerging risk factors are likely to be involved in these patients. As many authors reported that high serum ferritin levels are associated with diabetes mellitus (DM) and hypertension (HTN), it may have role in the pathogenesis of ACS.So we designed this study to test the relation between hyperferritinemia and newly diagnosed acute coronary syndrome patients of Bangladesh.Methods: The study was an observational case control study done in Department of Cardiology, Dhaka Medical College Hospital, from January 2013 to December 2013. Newly diagnosed patients with acute coronary syndrome (ACS) in the age group of 30- 70 years, admitted in the coronary care unit (CCU) of Dhaka Medical College Hospital, Dhaka, within the study period were taken as cases and age & sex matched healthy subject with no history of ischemic heart disease (IHD) and with normal ECG were taken as control by purposive sampling. In our study, the number of cases and controls were 65 each. So, total number of subject was 130.Results: According to the serum ferritin level both cases and controls were divided into two sub groups: subjects with normal ferritin level and with hyperferritinaemia. Normal ferritin level was found in 35(53.8%) subjects of case group and 62(95.4%) subjects of control groups. Hyperferritinaemia was found in 30(46.2%) subjects of case group and 3(4.6%) subjects of control group. Hyperferritinaemia was found to be significantly higher in case group than in control group (p 〈 0.001).Conclusion: The study concludes that the serum ferritin level of patients with ACS was significantly higher than the control group.Bangladesh Heart Journal 2017; 32(2) : 89-93
    Type of Medium: Online Resource
    ISSN: 2521-3113 , 1024-8714
    URL: Article
    DOI: 10.3329/bhj.v32i2.36094
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2018
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  • 4
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    In-hospital Outcome of Acute Coronary Syndrome Patients with on-Admission Hyponatremia
    Bangladesh Academy of Sciences ; 2019
    In:  Cardiovascular Journal Vol. 11, No. 2 ( 2019-02-27), p. 139-146
    Details
    In: Cardiovascular Journal, Bangladesh Academy of Sciences, Vol. 11, No. 2 ( 2019-02-27), p. 139-146
    Abstract: Background: Coronary artery disease is the commonest form of heart disease and the leading cause of morbidity and mortality throughout the world. Electrolytes imbalance can lead to increase in hospital mortality and morbidity in acute coronary syndrome patients. Our objective was to find out and to compare in-hospital outcome of patients presenting with acute coronary syndrome with or without onadmission hyponatremia. Methods: A total of 336 patients were included in this study of which 59 patients were in group A (sodium level 〈 135 mmol/l). Group A was subdivided in Group A1 (Na+-134-130mmol/l), Group A2 (Na+-120- 129mmol/l), Group A3 (Na+- 〈 120mmol/l) and 277 patients were in group B (sodium level 〉 135 mmol/l). Results: On-admission hyponatremia was documented in 16.12 %( 59) of patients with acute coronary syndrome. Among them, 16 patients with acute anterior STEMI, 19 patients with acute inferior STEMI, 19 patients with NSTEMI and 5 patients with unstable angina. In this study, in hospital complications like acute heart failure (81.4% vs. 29.2%, p 〈 0.05), cardiogenic shock (32.2% vs. 15.5%, p 〈 0.05) and in hospital mortality (6.8% vs. 1.1%, p 〈 0.05) were significantly more in the patients with hyponatremia. The frequency of in hospital mortality, acute heart failure and arrhythmia progressively increased with increasing severity of hyponatremia. Logistic regression analysis showed low plasma sodium level was independently associated with in hospital mortality (â =2.13, P =0.027, OR = 8.388, 95% CI 1.268 - 55.488). Conclusion: In this study on-admission hyponatremia significantly associated with high in-hospital adverse outcome in acute coronary syndrome patients. Cardiovasc. j. 2019; 11(2): 139-146
    Type of Medium: Online Resource
    ISSN: 2309-6357 , 2071-0917
    URL: Article
    DOI: 10.3329/cardio.v11i2.40414
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2019
    detail.hit.zdb_id: 2586638-2
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  • 5
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    In-hospital Outcome of Patients Presenting with Acute Anterior STEMI with Complete Right Bundle Branch Block
    Bangladesh Academy of Sciences ; 2018
    In:  Cardiovascular Journal Vol. 11, No. 1 ( 2018-09-14), p. 31-38
    Details
    In: Cardiovascular Journal, Bangladesh Academy of Sciences, Vol. 11, No. 1 ( 2018-09-14), p. 31-38
    Abstract: Background: Patients with acute anterior ST-segment elevation myocardial infarction (STEMI) and right bundle-branch block (RBBB) have high mortality risk, which may be stratified by early ECG changes. Our objective was to find out and to compare in-hospital outcome of patients presenting with acute anterior STEMI with or without complete RBBB.Methods: This prospective cohort study was conducted in the Department of Cardiology, Dhaka Medical College Hospital, Dhaka, over a period of one year from March 2016 to February 2017. A total of 184 patients were included in this study of which 32 patients were included in group A (acute anterior STEMI with complete RBBB) and 152 patients were included in group B (acute anterior STEMI without any BBB or fascicular block).Results: RBBB was documented in 17.4% (32) of patients with acute anterior STEMI. Acute LVF (50.0% vs. 26.3%, p 〈 0.05), Cardiogenic shock (31.3% vs. 13.2%, p 〈 0.05) and mortality (21.9% vs 7.9%, P 〈 0.05) were more frequently observed in patients with complete RBBB in comparison to patients without any BBB or fascicular block (FB). Among the AMI patients with RBBB, permanent RBBB was associated with a greater incidence of acute LVF (54.2% vs 37.5%, p 〉 0.05), cardiogenic shock (37.5% vs 12.5%, p 〉 0.05) and mortality (25% vs 12.5%, p 〉 0.05).Conclusion: In this study right bundle branch block accompanying acute anterior STEMI was associated with high in-hospital adverse outcomes.Cardiovasc. j. 2018; 11(1): 31-38
    Type of Medium: Online Resource
    ISSN: 2309-6357 , 2071-0917
    URL: Article
    DOI: 10.3329/cardio.v11i1.38239
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2018
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  • 6
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    Comparison of Diagnostic Criteria to Detect Undiagnosed Diabetes in Acute Coronary Syndrome Patients with Admission Hyperglycemia
    Bangladesh Academy of Sciences ; 2015
    In:  Cardiovascular Journal Vol. 8, No. 1 ( 2015-08-28), p. 35-42
    Details
    In: Cardiovascular Journal, Bangladesh Academy of Sciences, Vol. 8, No. 1 ( 2015-08-28), p. 35-42
    Abstract: Background: Diabetes mellitus is one of the most important risk factors of coronary artery disease. Admission hyperglycemia adversely influences the outcome of acute coronary syndrome patients. The study was conducted to compare the various diagnostic methods for the detection of undiagnosed diabetes mellitus in acute coronary syndrome patients with admission hyperglycaemia in Bangladeshi population.Methods: It was a cross sectional comparative study involving 157 patients with admission blood glucose level e7.8 mmol/l. Fasting plasma glucose, Glycated haemoglobin, pre-discharge oral glucose tolerance test was measured in all subjects and comparison of performance of different methods was done.Results: Oral glucose tolerance test revealed that in spite of admission hyperglycaemia, 57 (36.3%) patients were diabetic and 52 (33.12%) patients had impaired glucose homeostasis and 48 (30.57%) patients had normal glucose metabolism. Undiagnosed diabetes could not be adequately predicted with admission plasma glucose, fasting plasma glucose or HbA1c alone (area under the ROC curve 0.589, 0.825 and 0.852 respectively).Conclusion: Admission hyperglycaemia does not diagnose diabetes reliably in a stressful condition like acute coronary syndrome. Although neither admission plasma glucose, fasting plasma glucose, nor HbA1c level were as good as oral glucose tolerance test in detecting true diabetes, but combined fasting plasma glucose & HbA1c were found to be more sensitive & specific screening tool for detecting unknown diabetes in acute coronary syndrome patients with admission hyperglycaemia.Cardiovasc. j. 2015; 8(1): 35-42
    Type of Medium: Online Resource
    ISSN: 2309-6357 , 2071-0917
    URL: Article
    DOI: 10.3329/cardio.v8i1.24766
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2015
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  • 7
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    Recurrent Seizure: An Uncommon Presentation of Post Thyroidectomy Hypoparathyroidism
    Bangladesh Academy of Sciences ; 2015
    In:  Journal of Medicine Vol. 16, No. 1 ( 2015-02-25), p. 56-58
    Details
    In: Journal of Medicine, Bangladesh Academy of Sciences, Vol. 16, No. 1 ( 2015-02-25), p. 56-58
    Abstract: Basal ganglia calcification is associated with chronic hypoparathyroidism. We report a case of 37 year old lady with long standing iatrogenic hypoparathyroidism following total thyroidectomy. The clinical evaluation revealed neurological symptoms but without any neurological deficit. The CT scan of head showed calcification in caudate nucleus and part of lentiform nucleus of basal ganglia and in the cortical and subcortical white matter. Detection of brain calcinosis in patients who had total thyroidectomy can guide clinicians to further investigation for possible hypoparathyroidism.DOI: http://dx.doi.org/10.3329/jom.v16i1.22406 J MEDICINE 2015; 16 : 56-58
    Type of Medium: Online Resource
    ISSN: 2075-5384 , 1997-9797
    URL: Article
    DOI: 10.3329/jom.v16i1.22406
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2015
    detail.hit.zdb_id: 2549281-0
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  • 8
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    Association of Serum Vitamin D level with in-hospital Outcome in Patients with Acute Myocardial infarction
    Bangladesh Academy of Sciences ; 2022
    In:  Bangladesh Heart Journal Vol. 37, No. 2 ( 2022-12-28), p. 89-98
    Details
    In: Bangladesh Heart Journal, Bangladesh Academy of Sciences, Vol. 37, No. 2 ( 2022-12-28), p. 89-98
    Abstract: Objective: Vitamin D deficiency is emerging as a new risk factor for various cardiovascular events. Several studies have been done to find out association of vitamin D level with CAD with varying Results. Very few studies, however, have investigated the association between serum vitamin D levels and clinical outcomes in ACS patients thus far. The  Objective of this study was to assess the association between serum vitamin D levels and in-hospital complications of AMI patients in Department of Cardiology, Dhaka Medical College Hospital (DMCH), Dhaka. Methods: This was a cross-sectional observational study. We measured serum vitamin D level in AMI (STEMI and NSTEMI) patients (n=198) admitted in Department of Cardiology, DMCH. Patients with normal vitamin D level (e”30 ng/ml) were considered as Group I and patients with low serum vitamin D level ( 〈 30 ng/ml) were considered as Group II; and in-hospital complications were evaluated. Results: The study showed that 51% of study subjects of AMI had in-hospital complications; 71.1% patients with low vitamin D level had adverse in-hospital outcome whereas 14.3% patients with normal vitamin D level had AMI complications which was statistically significant (p 〈 0.001). Heart failure and arrhythmias were the most frequently observed complications. The Results of the study demonstrates that the association between low vitamin D level and in-hospital complications after AMI remains statistically significant (p 〈 0.001). Conclusions: Low serum vitamin D level is independently associated with a higher frequency of several in-hospital adverse clinical events including mortality after acute myocardial infarction (STEMI and NSTEMI). Whether low vitamin D levels represent a risk marker or a risk factor in ACS remains to be elucidated. Bangladesh Heart Journal 2022; 37(2): 89-98
    Type of Medium: Online Resource
    ISSN: 2521-3113 , 1024-8714
    URL: Article
    DOI: 10.3329/bhj.v37i2.63132
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2022
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  • 9
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    Sudden Cardiac Death in Three Generations of the Same Family: A case report
    Bangladesh Academy of Sciences ; 2015
    In:  Cardiovascular Journal Vol. 8, No. 1 ( 2015-08-28), p. 73-77
    Details
    In: Cardiovascular Journal, Bangladesh Academy of Sciences, Vol. 8, No. 1 ( 2015-08-28), p. 73-77
    Abstract: Every one of us has heard about tragic and sudden death of a healthy young person and which is often stated as inexplicable. The current case report focuses on a 20 year old young man with hypertrophic cardiomyopathy facing premature death with history of similar sudden premature death of his grandmother, father and brother. Hypertrophic cardiomyopathy is the commonest cause of sudden cardiac death in young adults and is also an important substrate for heart failure disability at any age.Cardiovasc. j. 2015; 8(1): 73-77
    Type of Medium: Online Resource
    ISSN: 2309-6357 , 2071-0917
    URL: Article
    DOI: 10.3329/cardio.v8i1.24779
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2015
    detail.hit.zdb_id: 2586638-2
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  • 10
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    Effect of Serum Homocysteine on Coronary Artery Disease in Younger and Older Ischaemic Heart Disease Patients
    Bangladesh Academy of Sciences ; 2016
    In:  Cardiovascular Journal Vol. 8, No. 2 ( 2016-02-25), p. 138-142
    Details
    In: Cardiovascular Journal, Bangladesh Academy of Sciences, Vol. 8, No. 2 ( 2016-02-25), p. 138-142
    Abstract: Background: Hyperhomocysteinemia is known as an independent risk factor of atherosclerosis. But the probable role of Hyperhomocysteinemia in Premature Coronary Artery Disease (CAD) is not well studied. The aim of this study was to assess the role of serum homocysteine on angiographically documented CAD in younger and older ischaemic heart disease (IHD) patients.Methods: Total 120 patients with IHD admitted in the Department of Cardiology, Dhaka Medical College Hospital for CAG were selected by purposive sampling method and divided into two groups. 60 patients in Group-I, d 40 years of age (Younger); 60 patients in Group-II, 〉 40 years of age (Older). Homocysteine was measured in all patients and other demographical and clinical data were collected. Homocysteine level was correlated with the presence and severity of CAD.Results: Smoking, positive family history of IHD, dyslipidaemia and hyper homocysteinemia were important risk factors in younger IHD patients. Whereas, hypertension, diabetes mellitus and dyslipidaemia were important cardiovascular risk factors in older age group. Obesity was not an important risk factors as evidenced by mean BMI. Serum homocysteine was not well related to presence of CAD or extent of CAD in older IHD patients. However in younger patients hyperhomocysteinemia was related to both presence and severity of CAD.Conclusion: In younger IHD patients hyperhomocysteinemia is an important cardiovascular risk factor. But in older patients it loses its significance. So serum homocysteine level should be screened routinely in younger IHD patients.Cardiovasc. j. 2016; 8(2): 138-142
    Type of Medium: Online Resource
    ISSN: 2309-6357 , 2071-0917
    URL: Article
    DOI: 10.3329/cardio.v8i2.26817
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2016
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