In:
Annals of Noninvasive Electrocardiology, Wiley, Vol. 25, No. 1 ( 2020-01)
Abstract:
Several noninvasive risk factors (NIRFs) have been proposed for sudden cardiac death risk stratification in post‐myocardial infarction (post‐MI) patients with preserved ejection fraction (EF). However, it remains unclear if these factors change over time. Methods We evaluated seven electrocardiographic NIRFs as they were described in the PRESERVE‐EF trial in 80 post‐MI patients with EF ≥ 40%, at least 40 days after revascularization and 1 year later. Results Mean patient age was 56 ± 10 years, and 88% were men. Mean EF was 50 ± 5%. The prevalence of (a) positive late potentials (27.5% vs. 28.8%, p = .860), (b) 〉 30 premature ventricular complexes/hour (8.8% vs. 11.3%, p = .598), (c) nonsustained ventricular tachycardia (8.8% vs. 5%, p = .349), (d) standard deviation of normal RR intervals 〈 75 ms (3.8% vs. 3.8%, p = 1.000), (e) QTc derived from 24‐hr electrocardiography 〉 440 ms (men) or 〉 450 ms (women) (17.5% vs. 17.5%, p = 1.000), (f) deceleration capacity ≤4.5 ms and heart rate turbulence onset ≥0% and slope ≤2.5 ms (2.5% vs. 3.8%. p = 1.000), and (g) ambulatory T‐wave alternans ≥65 μV in two Holter channels (6.3% vs. 6.3%, p = 1.000) were similar between the two measurements. However, five patients (6.3%) without any NIRFs during the first assessment had at least one positive NIRF at the second assessment and six patients (7.5%) with at least one NIRF at baseline had no positive NIRFs at 1 year. Conclusions While the prevalence of the examined electrocardiographic NIRFs between the two examinations was similar on a population basis, some patients without NIRFs at baseline developed NIRFs at 1 year and vice versa, highlighting the need for risk factor reassessment during follow‐up.
Type of Medium:
Online Resource
ISSN:
1082-720X
,
1542-474X
Language:
English
Publisher:
Wiley
Publication Date:
2020
detail.hit.zdb_id:
2111515-1
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