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  • 1
    In: Antimicrobial Resistance & Infection Control, Springer Science and Business Media LLC, Vol. 6, No. S2 ( 2017-2)
    Type of Medium: Online Resource
    ISSN: 2047-2994
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2017
    detail.hit.zdb_id: 2666706-X
    SSG: 15,3
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  • 2
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2017
    In:  Journal of Armed Forces Medical College, Bangladesh Vol. 13, No. 1 ( 2017-04-23), p. 95-98
    In: Journal of Armed Forces Medical College, Bangladesh, Bangladesh Academy of Sciences, Vol. 13, No. 1 ( 2017-04-23), p. 95-98
    Abstract: Introduction: Now a days Magnetic Resonance Imaging (MRI) has become the primary investigation for the assessment of knee injuries. Non-invasive MRI has the ability of high resolution and accuracy to diagnose the knee injuries and it can be the alternative to diagnostic arthroscopy. Objective: To validate MRI evaluation in the assessment of cruciate ligamentous and meniscal injuries of the knee joint and compare with arthroscopic findings. Materials and Methods: This cross sectional study was conducted at Combined Military Hospital, Dhaka from 01 January 2013 to 30 June 2013 where sixty patients who had the history of twisting injuries to the knee were selected in this study. Along with injury history they were strongly suspected to have meniscal and/or cruciate ligamentous tears. Then they were examined by open MRI machine 0.4 tesla, Hitachi, made in Japan. A Quadrature (QD) extremity coil was used in this study. Spin echo T1, fast spin echo T2 and Short Tau Inversion Recovery (STIR) sequences were taken in direct coronal, sagittal and axial planes with 4mm slice thickness. Data were recorded and statistical analysis was done by SPSS version 20. Results: Total 60 patients underwent MRI and Arthroscopic examination. The final diagnosis was established by direct findings at Arthroscopic examination. The Sensitivity, Specificity and Accuracy of Magnetic Resonance Imaging in the diagnosis of cruciate ligamentous and meniscal injuries as compared to arthroscopy were Anterior Cruciate Ligament (ACL): 96.88% sensitivity, 96.43% specificity, 96.66% accuracy, 96.87% Positive predictive value (PPV) and 96.42% Negative predictive value (NPV); Medial Meniscus (MM): 96.43% sensitivity, 98.87% specificity,96.66% accuracy, 96.42% PPV and 98.88% NPV; for Lateral Meniscus (LM): 80.00% sensitivity, 97.77% specificity, 93.33% accuracy, 92.30% PPV and 93.62% NPV. Conclusion: As a non-invasive diagnostic modality Magnetic Resonance Imaging is very useful and having high sensitivity, specificity and accuracy in the detection of meniscal and cruciate ligament injuries. To prevent unwanted arthroscopies MRI should be done in every patient of suspected cruciate ligamentous and meniscal injury before doing arthroscopy. Journal of Armed Forces Medical College Bangladesh Vol.13(1) 2017: 95-98
    Type of Medium: Online Resource
    ISSN: 1992-5743
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2017
    detail.hit.zdb_id: 2573882-3
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  • 3
    In: Cardiovascular Journal, Bangladesh Academy of Sciences, Vol. 16, No. 1 ( 2023-10-02), p. 17-23
    Abstract: Background: Heparin is an anticoagulant used invariably in all cardiac surgery. Heparin dosing and its reversal is determined by monitoring Activated Clotting Time (ACT). Surgery under cardiopulmonary bypass requires much more heparin than off-pump cardiac operations. Intermittent heparin dosing after initial bolus dose is widely practiced to maintain ACT level 200- 300 seconds in OPCAB. Fluctuation of ACT level from this range may causes adverse postoperative outcome. This study was aimed to compare early postoperative outcome between intermittent heparin dose and continuous heparin infusion after initial bolus dose during OPCAB. Methods: This comparative cross-sectional study was carried out in National Institute of Cardiovascular Diseases (NICVD) from January 2019 to December 2020. Total 110 patients were enrolled by purposive sampling and divided into 2 groups: group-A where 55 patients received intermittent heparin after initial bolus dose and group-B where 55 patients received continuous heparin infusion after initial bolus dose. Data were analyzed by statistical package for social science (SPSS) version 26.0 and p value 〈 0.05 was considered significant. Results: Baseline ACT level of group-A was 87.04±5.51 seconds and group-B was 87.31±5.74 seconds, which was not significant (p = 0.800). After bolus dose of Heparin, ACT level of group-A was 252.02 ± 25.131 seconds and group-B was 259.04 ± 12.645 seconds. Difference between the groups was not significant (p = 0.068). Mean maintenance ACT was 326.34±22.774 seconds in group-A and 258.67±12.285 seconds in group-B patient, which was significant (p 〈 0.001). Peroperatively 29% from group-A and 11% from group-B developed arrhythmia. Postoperative mean Troponin I level in group-A was 5.78± 1.15 and group-B was 5.32± 1.05 ng/dl, which is significant (p = 0.030). Postoperative blood loss was significantly higher in group-A than group-B (986.36± 398.31 vs 852.73±241.22, p=0.036). There was significantly better reduction of arrhythmia and ischemia in postoperative and on discharge ECG finding in group-B patients (p=0.002). On discharge echocardiography 31% from group-A and 13% from group-B had regional wall motion abnormality, which is significant (p=0.018). But there was no significant difference in LVEF% (52.65±5.99 vs 53.85±5.77, p = 0.287). There was only one mortality which was from group-A. The patient was suffering from critical left main disease and developed postoperative arrhythmia and low output syndrome. Conclusion: Early postoperative outcome of continuous heparin infusion is better than intermittent intravenous heparin after initial bolus dose during Off-pump coronary artery bypass surgery. So, during OPCAB use of continuous heparin infusion after bolus dose is eminent time worthy. Cardiovasc j 2023; 16(1): 17-23
    Type of Medium: Online Resource
    ISSN: 2309-6357 , 2071-0917
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2023
    detail.hit.zdb_id: 2586638-2
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  • 4
    In: Sustainability, MDPI AG, Vol. 14, No. 1 ( 2022-01-01), p. 448-
    Abstract: Despite the significant number of fatalities and injuries, there is currently a lack of data on public knowledge, attitudes, and practices regarding lightning in Bangladesh. This study aims to assess the public’s knowledge, attitude, and practices (KAP) towards lightning in the country. A total of 1641 individuals participated in an online KAP survey. Where appropriate, the Kruskal–Wallis or Mann–Whitney U test, Spearman’s rank correlation, and logistic regression models were performed. About 65% of the survey population reported frequent lightning; most (72.64%) did not receive any warning messages, and small proportions (22.12%) had lightning safety precautions. Individuals with numerous lightning experiences perceived considerably unsafe places against lightning compared to infrequent lightning experiences (p 〈 0.05). Respondents reported good knowledge (56.06%), positive attitudes (82.27%), and good preventive practices (72.33%). The logistic regression demonstrated that having good knowledge and positive attitudes can help people practice lightning safety. Females demonstrated better lightning attitudes and practices compared to males. In comparison to urban residents, rural residents had poor practices. In addition, individuals’ educational levels might also play a crucial role in preparing them for lightning. Overall, extensive lightning campaign activities combined with effective education are required for the behavioral changes in this lightning-vulnerable society.
    Type of Medium: Online Resource
    ISSN: 2071-1050
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2518383-7
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  • 5
    In: Water, MDPI AG, Vol. 12, No. 7 ( 2020-07-21), p. 2073-
    Abstract: (1) Background: Residents of Dhaka slums frequently lack clean and functional shared latrines. We explored the role of landlords and compound managers in promoting latrine cleanliness in the intervention arm of a randomized trial; (2) Methods: We conducted focus group discussions, key informant interviews, and in-depth interviews with community health promoters, landlords, and compound managers to better understand the decision-making process, barriers to contributing to sanitation, and cleanliness of shared latrines. (3) Results: Landlords’ and compound managers’ engagement in promoting clean and functional latrines depended, in part, on their own proximity to the properties they own and manage. The compound managers played a leadership role through engagement with health promoters, oversight of implementation of a cleaning schedule, and support for installation and maintenance of sanitation hardware, resulting in improved sanitation practices; (4) Conclusions: Interventions in slums in Bangladesh should consider engaging landlords and compound managers in efforts to bring about structural and organizational changes to support the adoption of improved water, sanitation, and hygiene practices.
    Type of Medium: Online Resource
    ISSN: 2073-4441
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2521238-2
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  • 6
    In: Brain and Behavior, Wiley, Vol. 10, No. 3 ( 2020-03)
    Abstract: Beck Depression Inventory (BDI‐II) is a widely used valid instrument to assess the severity of depression in clinical and normal settings. To meet the necessity of a standard scale for measuring depression among above 265 million Bangla speaking population around the world, this scale was translated and validated. Methods Two translations of BDI‐II into Bangla were prepared, and then, two back translations were done by medical and language experts in parallel. Thereafter, sentence revision followed by pretest on 20 respondents was done to finalize the Bangla version of BDI‐II (BDI‐II BV). Afterward, a cross‐sectional, comparative, and descriptive study was conducted to validate the scale by purposive sampling technique consisting of 111 persons (both clinical and normal) in three tertiary‐level hospitals in Bangladesh. Everyone was given to fill up BDI‐II BV at first. Then, they were given to fill up BDI‐II BV ( n  = 49), Bangla version of Depression Anxiety Stress Scales 21‐item (DASS21‐BV, n  = 47) and BDI‐II ( n  = 25) 3–7 days later. The diagnosis of depressive disorder was made according to DSM‐5. Correlation study and factor analysis were completed. Results The mean age was 28.83(±8.70) years. The male–female ratio was 1:0.82. Correlation of scores for BDI‐II BV with the DASS21‐BV depression subscale was .920; BDI‐II BV with BDI‐II was .985 (Cronbach's α .993; t test not significant) and BDI‐II BV applied first and the second time was .960 (Cronbach's α .979; z test not significant). The interitem correlation for all the items was found highly significant ( p   〈  .01). Patients having depressive disorder or episodes had significantly higher BDI‐II BV scores than normal ( M  +  SD 30.18 + 10.127 than 8.34 + 5.910; p   〈  .001). Partial confirmatory factor analysis demonstrated two‐factor loading comprising Cognitive and Somatic‐affective symptoms. Conclusions Through the translation and validation process, a validated Bangla version of BDI‐II was produced to measure depression and its severity among the Bengali population.
    Type of Medium: Online Resource
    ISSN: 2162-3279 , 2162-3279
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2623587-0
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  • 7
    In: Tropical Medicine & International Health, Wiley, Vol. 24, No. 8 ( 2019-08), p. 972-986
    Abstract: L'effet sur le comportement des programmes de promotion du lavage des mains à grande échelle a été rarement évalué et aucune variation de cet effet dans le temps n'a été décrite. Nous évaluons les effets d'un programme de promotion du lavage des mains à grande échelle sur les résultats dans un cadre communautaire à Dhaka, au Bangladesh. Méthodes Nous avons analysé les données d'un essai randomisé par grappes comprenant 3 groupes: intervention vaccin‐changement de comportement ( VBC ), vaccin uniquement (V) et aucune intervention (contrôle). Les collecteurs de données ont sélectionné au hasard différents sous‐ensembles de ménages chaque mois au cours de la période d’étude et ont évalué: 1) la variation temporelle de la disponibilité de savon et d'eau sur le lieu de lavage des mains, 2) l'utilisation d'eau et de savon par les participants lorsqu'on leur a demandé de faire la démonstration du lavage des mains, 3) le comportement du lavage des mains selon une observation structurée. Nous avons utilisé des analyses de régression log‐binomiales pour calculer les ratios de prévalence ( PR ) et les intervalles de confiance à 95%, ainsi que pour comparer les résultats par groupe d’étude. Résultats Les collecteurs de données ont interrogé 9325 ménages au cours de 28 mois. Dans le groupe VBC , il y avait une tendance positive significative sur la disponibilité d'eau et de savon de la ligne de base à 9 mois après le début de l'intervention ( p ‐pour‐tendances 〈 0,001) et aucune tendance significative au cours des mois 10 à 28 ( p ‐pour‐ tendance = 0,297). Sur l'ensemble de la période d’étude, la disponibilité en eau et en savon était plus élevée dans le groupe VBC (43%) que dans le groupe V (23%) ( PR = 1,92; IC : 1,72 ‐ 2,15) et dans le groupe contrôle (28%) ( PR = 1,53; IC : 1,38 ‐ 1,69). Il n'y avait pas de différence entre les groupes d’étude en ce qui concerne l'utilisation de savon lors de démonstrations de lavage des mains. Le lavage des mains observé avec du savon après l'utilisation des toilettes était plus élevé dans le groupe VBC (17%) que dans le groupe V (8%) ( PR = 1,47; IC : 0,58 ‐ 3,75) et dans le groupe témoin (2%) ( PR = 3,47, IC : 0,48 ‐ 23,33). Lors d'autres événements possibles de transmission d'agents pathogènes, la fréquence du lavage des mains au savon était ≤ 3%. Conclusion Les ménages du groupe VBC ont maintenu du savon et de l'eau pour se laver les mains, mais la prévalence du lavage des mains observé était faible dans tous les groupes de l’étude. Les résultats soulignent la nécessité de renforcer les approches évolutives de changement de comportement.
    Type of Medium: Online Resource
    ISSN: 1360-2276 , 1365-3156
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2018112-7
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  • 8
    In: Clinical Infectious Diseases, Oxford University Press (OUP), Vol. 73, No. 9 ( 2021-11-02), p. e2560-e2568
    Abstract: The Cholera Hospital-Based Intervention for 7 Days (CHoBI7) mobile health (mHealth) program was a cluster-randomized controlled trial of diarrhea patient households conducted in Dhaka, Bangladesh. Methods Patients were block-randomized to 3 arms: standard message on oral rehydration solution use; health facility delivery of CHoBI7 plus mHealth (no home visits); and health facility delivery of CHoBI7 plus 2 home visits and mHealth. The primary outcome was reported diarrhea in the past 2 weeks collected monthly for 12 months. The secondary outcomes were stunting, underweight, and wasting at a 12-month follow-up. Analysis was intention-to-treat. Results Between 4 December 2016 and 26 April 2018, 2626 participants in 769 households were randomly allocated to 3 arms: 849 participants to the standard message arm, 886 to mHealth with no home visits arm, and 891 to the mHealth with 2 home visits. Children & lt;5 years had significantly lower 12-month diarrhea prevalence in both the mHealth with 2 home visits arm (prevalence ratio [PR]: 0.73 [95% confidence interval {CI}, .61–.87] ) and the mHealth with no home visits arm (PR: 0.82 [95% CI, .69–.97]). Children & lt;2 years were significantly less likely to be stunted in both the mHealth with 2 home visits arm (33% vs 45%; odds ratio [OR]: 0.55 [95% CI, .31–.97] ) and the mHealth with no home visits arm (32% vs 45%; OR: 0.54 [95% CI, .31–.96]) compared with children in the standard message arm. Conclusions The CHoBI7 mHealth program lowered pediatric diarrhea and stunting among diarrhea patient households. Clinical Trials Registration NCT04008134.
    Type of Medium: Online Resource
    ISSN: 1058-4838 , 1537-6591
    RVK:
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 2002229-3
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  • 9
    In: Tropical Medicine & International Health, Wiley, Vol. 22, No. 8 ( 2017-08), p. 1000-1011
    Abstract: This paper accompanies the following article: Saxton RE, Yeasmin F, Alam M‐U et al. If I do not have enough water, then how could I bring additional water for toilet cleaning?! Addressing water scarcity to promote hygienic use of shared toilets in Dhaka, Bangladesh, doi: 10.1111/tmi.12914 .
    Type of Medium: Online Resource
    ISSN: 1360-2276 , 1365-3156
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2018112-7
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  • 10
    In: Frontiers in Oncology, Frontiers Media SA, Vol. 12 ( 2022-6-1)
    Abstract: Salvicine is a new diterpenoid quinone substance from a natural source, specifically in a Chinese herb. It has powerful growth-controlling abilities against a broad range of human cancer cells in both in vitro and in vivo environments. A significant inhibitory effect of salvicine on multidrug-resistant (MDR) cells has also been discovered. Several research studies have examined the activities of salvicine on topoisomerase II (Topo II) by inducing reactive oxygen species (ROS) signaling. As opposed to the well-known Topo II toxin etoposide, salvicine mostly decreases the catalytic activity with a negligible DNA breakage effect, as revealed by several enzymatic experiments. Interestingly, salvicine dramatically reduces lung metastatic formation in the MDA-MB-435 orthotopic lung cancer cell line. Recent investigations have established that salvicine is a new non-intercalative Topo II toxin by interacting with the ATPase domains, increasing DNA–Topo II interaction, and suppressing DNA relegation and ATP hydrolysis. In addition, investigations have revealed that salvicine-induced ROS play a critical role in the anticancer-mediated signaling pathway, involving Topo II suppression, DNA damage, overcoming multidrug resistance, and tumor cell adhesion suppression, among other things. In the current study, we demonstrate the role of salvicine in regulating the ROS signaling pathway and the DNA damage response (DDR) in suppressing the progression of cancer cells. We depict the mechanism of action of salvicine in suppressing the DNA–Topo II complex through ROS induction along with a brief discussion of the anticancer perspective of salvicine.
    Type of Medium: Online Resource
    ISSN: 2234-943X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2649216-7
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