In:
Angewandte Chemie, Wiley, Vol. 129, No. 11 ( 2017-03-06), p. 2969-2972
Abstract:
Understanding the formation process of nanoparticles is of the utmost importance to improve their design and production. This especially holds true for self‐assembled nanoparticles whose formation processes have been largely overlooked. Herein, we present a new technology that integrates a microfluidic‐based nanoparticle synthesis method and Förster resonance energy transfer (FRET) microscopy imaging to visualize nanoparticle self‐assembly in real time. Applied to different nanoparticle systems, for example, nanoemulsions, drug‐loaded block‐copolymer micelles, and nanocrystal‐core reconstituted high‐density lipoproteins, we have shown the approach's unique ability to investigate key parameters affecting nanoparticle formation.
Type of Medium:
Online Resource
ISSN:
0044-8249
,
1521-3757
DOI:
10.1002/ange.v129.11
DOI:
10.1002/ange.201611288
Language:
English
Publisher:
Wiley
Publication Date:
2017
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505868-5
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506609-8
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514305-6
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505872-7
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1479266-7
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505867-3
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506259-7
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