In:
American Journal of Veterinary Research, American Veterinary Medical Association (AVMA), Vol. 61, No. 11 ( 2000-11-01), p. 1358-1363
Abstract:
Objective —To compare molecular associations
between the vesicular stomatitis virus (VSV)-New Jersey isolates of the 1995 outbreak with those from
previous outbreaks between 1982 and 1985 in the western United States. Sample Population —23 virus isolates considered
representative of the 1995 outbreak of vesicular stomatitis. Procedure —Viral gene coding for surface-envelope
protein G was evaluated by use of nucleotide sequencing and phylogenetic analysis. Results —Changes in up to 0.77% of the nucleotide
bases and 1.35% of the amino acids were detected among the 1995 viral isolates, whereas changes in up
to 3.2 and 2.9% of the nucleotides and amino acids, respectively, were found, compared with the 1982 to
1985 viruses. Insertions or deletions were not found in the entire gene, which spanned 1,554 nucleotide
bases. Conclusions and Clinical Relevance —Phylogenetic
analysis indicated that the 1995 VSV-New Jersey belongs to a lineage distinct from that of the 1982 to
1985 viruses that caused previous outbreaks in the western United States. Furthermore, it also is distinct
from strains from Central America and from the Georgian Hazelhurst strain. ( Am J Vet Res 2000;
61:1358–1363)
Type of Medium:
Online Resource
ISSN:
0002-9645
DOI:
10.2460/ajvr.2000.61.1358
Language:
Unknown
Publisher:
American Veterinary Medical Association (AVMA)
Publication Date:
2000
detail.hit.zdb_id:
2056942-7
SSG:
22
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