In:
Angiology, SAGE Publications, Vol. 63, No. 2 ( 2012-02), p. 119-126
Abstract:
The prognostic value of admission estimated glomerular filtration rate (eGFR) calculated by the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula for cardiovascular adverse outcomes in acute coronary syndrome (ACS) was explored. Baseline eGFR was classified as no renal dysfunction ( 〉 90 mL/min per 1.73 m 2 ), borderline (90-60.1 mL/min per 1.73 m 2 ), moderate (60-30.1 mL/min per 1.73 m 2 ), or severe (≤30 mL/min per 1.73 m 2 ) renal dysfunction. Of the 5034 patients, 3415 (67.8%) had eGFR 〈 90. Compared to patients with an eGFR ≥60 mL/min per 1.73 m 2 , patients with 〈 60 mL/min per 1.73 m 2 were less likely to be treated with β-blockers, angiotensin-converting enzyme inhibitors, or statins, or to undergo percutaneous coronary interventions. Lower eGFR showed a stepwise association with significantly worse adverse in-hospital outcomes. The adjusted odds ratio of in-hospital death with an eGFR 〈 30 mL/min per 1.73 m 2 was 3.1 (95% confidence interval 1.1-8.4, P = .0324), compared with an eGFR 〉 90 mL/min per 1.73 m 2 . Estimated glomerular filtration rate calculated by the new CKD-EPI is an independent predictor of major adverse cardiac outcomes in patients with ACS.
Type of Medium:
Online Resource
ISSN:
0003-3197
,
1940-1574
DOI:
10.1177/0003319711409565
Language:
English
Publisher:
SAGE Publications
Publication Date:
2012
detail.hit.zdb_id:
2065911-8
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