In:
Tumori Journal, SAGE Publications, Vol. 103, No. 1_suppl ( 2017-11), p. S73-S77
Abstract:
Carcinoma ex-pleomorphic adenoma of the parapharyngeal space is an exceedingly rare entity. Methods The clinical records of two patients with primary carcinoma ex-pleomorphic adenoma of the parapharyngeal space surgically treated at two different centers were retrospectively analyzed. Results Despite ultrasound-guided fine-needle aspiration cytology and magnetic resonance imaging, the correct diagnosis was preoperatively missed in both cases. Excision was obtained through a transcervical-transparotid approach in 1 case and a minimally-invasive endoscopic-assisted transcervical approach in the other. Definitive histology was consistent with intracapsular carcinoma ex-pleomorphic adenoma. Adjuvant radiotherapy was performed in the case with macroscopic malignant degeneration; both patients are alive and free from disease 36 months after surgery. Conclusions Carcinoma ex-pleomorphic adenoma of the parapharyngeal space is a rare disease, and definitive diagnosis may be challenging. Surgery is the mainstay of treatment, but adjuvant radiotherapy also may be required in the presence of specific risk factors.
Type of Medium:
Online Resource
ISSN:
0300-8916
,
2038-2529
Language:
English
Publisher:
SAGE Publications
Publication Date:
2017
detail.hit.zdb_id:
280962-X
detail.hit.zdb_id:
2267832-3
Permalink