In:
Macromolecular Bioscience, Wiley, Vol. 9, No. 9 ( 2009-09-09), p. 842-848
Abstract:
Size tunable amphiphilic NPs composed of poly( γ ‐PGA) and hydrophobic amino acids, such as Phe or Trp, were prepared. To prepare these size‐regulated NPs, γ ‐PGA‐ g ‐Phe or γ ‐PGA‐ g ‐Trp dissolved in DMSO was added to various concentrations of NaCl solution. The γ ‐PGA‐Phe and γ ‐PGA‐Trp formed monodispersed NPs, and the size of NPs can be easily controlled by NaCl concentration. The different‐sized NPs showed the same structure. The encapsulation of protein into the different‐sized NPs was successfully achieved and the size of protein‐encapsulated γ ‐PGA‐Phe NPs was increased when protein was encapsulated. magnified image
Type of Medium:
Online Resource
ISSN:
1616-5187
,
1616-5195
DOI:
10.1002/mabi.200800367
Language:
English
Publisher:
Wiley
Publication Date:
2009
detail.hit.zdb_id:
2039130-4
SSG:
12
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