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  • 1
    Online Resource
    Online Resource
    Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences ; 2007
    In:  Acta Physica Sinica Vol. 56, No. 7 ( 2007), p. 3911-
    In: Acta Physica Sinica, Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences, Vol. 56, No. 7 ( 2007), p. 3911-
    Abstract: Photoacoustics as a potential and noninvasive medical imaging technology,it combines the advantages of ultrasound imaging and optical imaging to provide high ultrasonic resolution and high optical contrast tissue images. A reconstruction algorithm named the modified simultaneous iterative reconstruction technique (MSIRT) using in limited-view data in photoacoustic imaging was studied. The simulation and experiments result demonstrated that MSIRT has good performance in photoacoustic imaging for limited-view data at angles 90°,135° and 180°. It works much better than traditional algebraic reconstruction algorithm in rectification of the measurement and the speed of convergence. A circular scan with a single-element transducer system was used to obtain photoacoustic signals through 180° in the experiment. This technique provides a high contrast and high resolution (about 60μm) photoacoustic imaging of blood vessels of a chicken embryo based on MSIRT. It greatly reduced the data acquisition time. This method could be potentially used to realtime monitoring of cerebral blood flow and the vascular damage during photodynamic therapy.
    Type of Medium: Online Resource
    ISSN: 1000-3290 , 1000-3290
    Language: Unknown
    Publisher: Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences
    Publication Date: 2007
    Location Call Number Limitation Availability
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  • 2
    Online Resource
    Online Resource
    Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences ; 2009
    In:  Acta Physica Sinica Vol. 58, No. 7 ( 2009), p. 4610-
    In: Acta Physica Sinica, Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences, Vol. 58, No. 7 ( 2009), p. 4610-
    Abstract: Photoacoustic imaging combines advantages of both ultrasound imaging and optical imaging to provide high ultrasonic resolution and high optical contrast in noninvasive medical images. A photoacoustic computer tomography (PCT) system with a focused digital phased array transducer is proposed. In particular each element of the transducer array has a thin cylindrical ultrasonic lens to select 2D image plane and suppress the out-of-plane signals to realize photoacoustic computed tomography. A fast full-view photoacoustic imaging system for visualizing tissue structures using a linear transducer array with combined scan, whies; detects photoacoustic signals by combined electronic and mechanical scanning. An improved limited-field filtered back projection algorithm with directivity factors was applied to reconstruct the optical absorption distribution and further improve the lateral resolution. In the experiment, the spatial resolution of this imaging system is determined as 0.2mm, and the slice resolution of Z axis is 1.5mm. Mechanical step scanning was performed, leading to a measurement time of 6.4 seconds per position, and a total scan duration of 150 seconds to obtain the two-dimensional photoacoustic image. High spatial resolution of 2D photoacoustic vascular image and quasi-3D photoacoustic CT for breast cancer imaging are achicned. The experimental results demonstrate that this method and imaging system can realize the high resolution photoacoustic tomography wtich can be applied to noninvasive detection of early breast cancer.
    Type of Medium: Online Resource
    ISSN: 1000-3290 , 1000-3290
    Language: Unknown
    Publisher: Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences
    Publication Date: 2009
    Location Call Number Limitation Availability
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  • 3
    Online Resource
    Online Resource
    Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences ; 2009
    In:  Acta Physica Sinica Vol. 58, No. 7 ( 2009), p. 4760-
    In: Acta Physica Sinica, Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences, Vol. 58, No. 7 ( 2009), p. 4760-
    Abstract: Photoacoustic imaging is a novel noninvasive imaging technique of biological tissue that overcomes the overwhelming scattering of light in biological tissue by utilizing ultrasonic wave to translate the image signal. In this study, near-infrared light and indocyanine green as an optical contrast agent were used to achieve the cerebrovascular distribution by photoacoustic imaging. Near-infrared light penetrates deep into the brain tissues through the skin and skull, and the indocyanine green enhances the photoacoustic signals of the blood vessels. A photoacoustic angiography of vascular distribution in the mouse brain in vivo was acquired that matches the anatomical photograph well. The experimental result demonstrates the photoacoustic imaging with near-infrared light and optical contrast agent has the potential for functional and molecular biomedical imaging.
    Type of Medium: Online Resource
    ISSN: 1000-3290 , 1000-3290
    Language: Unknown
    Publisher: Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences
    Publication Date: 2009
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
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