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  • 1
    Online Resource
    Online Resource
    Survival of stress exposed Campylobacter jejuni in the murine macrophage J774 cell line
    Elsevier BV ; 2009
    In:  International Journal of Food Microbiology Vol. 129, No. 1 ( 2009-01), p. 68-73
    Details
    In: International Journal of Food Microbiology, Elsevier BV, Vol. 129, No. 1 ( 2009-01), p. 68-73
    Type of Medium: Online Resource
    ISSN: 0168-1605
    URL: Article
    DOI: 10.1016/j.ijfoodmicro.2008.11.010
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2009
    detail.hit.zdb_id: 2013748-5
    SSG: 12
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  • 2
    Online Resource
    Online Resource
    Probiotics for the Prevention of Acute Respiratory-Tract Infections in Older People: Systematic Review
    MDPI AG ; 2021
    In:  Healthcare Vol. 9, No. 6 ( 2021-06-07), p. 690-
    Details
    In: Healthcare, MDPI AG, Vol. 9, No. 6 ( 2021-06-07), p. 690-
    Abstract: The aim of this systematic review was to present the indirect influence of probiotics on the incidence and duration of acute upper respiratory-tract infections in older people, by regulating the immune system. Eight randomized, placebo-controlled clinical trials met the inclusion criteria, considering the threshold of older people being 60 years and over. Single strain probiotics were used in all studies, including three probiotic strains used in fermented foods: Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1, Lacticaseibacillus paracasei subsp. paracasei CNCM I-1518 and Lacticaseibacillusparacasei Shirota, and three probiotic strains used as food supplements: Loigolactobacillus coryniformis K8 CECT5711, Bacillus subtilis CU1 and Lacticaseibacillus rhamnosus GG. Current evidence showed that certain probiotic strains were better than a placebo in lowering the incidence or number of older people experiencing acute upper respiratory tract infections; however, not all probiotic strains were efficient, and not all studies reported statistically significant outcomes. More high quality large-scale properly controlled clinical studies focusing on older people are warranted.
    Type of Medium: Online Resource
    ISSN: 2227-9032
    URL: Article
    DOI: 10.3390/healthcare9060690
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2721009-1
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  • 3
    Online Resource
    Online Resource
    Virulence comparison of human and poultry Campylobacter jejuni isolates in a mouse model
    Knowledge Enterprise Journals ; 2017
    In:  Medical Research Archives Vol. 5, No. 10 ( 2017-10-15)
    Details
    In: Medical Research Archives, Knowledge Enterprise Journals, Vol. 5, No. 10 ( 2017-10-15)
    Abstract:  ABSTRACTObjective: Research into Campylobacter jejuni pathogenesis and host responses to C. jejuni infection is needed in the fight against human campylobacteriosis.Methods: We established intravenous infections of BALB/c mice with either a C. jejuni food isolate or C. jejuni of human origin. Further we include PCR to demonstrate the presence and stability of the putative virulence genes cadF, virbB11, cdtB, cdtC, ceuE in C. jejuni isolates and we examined cytokine production of IL-6, IL-12, TNF-α, IFN-γ, IL-10 in the livers of these infected mice.Results: We confirm here the presence of the cadF, cdtB, cdtC and ceuE genes in a food and a clinical C. jejuni isolate, with no sequence changes after the C. jejuni sub-culturing in a food model and when recovered from mouse liver after infection. Both of these C. jejuni isolates persisted in the mouse livers and activated comparable cytokine patterns for IL-12, TNF-α, IFN-γ and IL-10, with down-regulation of IL-6.Conclusions: These data show the comparability of these C. jejuni food and clinical isolates in terms of the prevalence and stability of their putative virulence genes and the outcome of disease during systemic murine campylobacteriosis.
    Type of Medium: Online Resource
    ISSN: 2375-1924 , 2375-1916
    URL: Article
    DOI: 10.18103/mra.v5i10.1581
    Language: Unknown
    Publisher: Knowledge Enterprise Journals
    Publication Date: 2017
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  • 4
    Online Resource
    Online Resource
    Virulence genes and cytokine profile in systemic murine Campylobacter coli infection
    Informa UK Limited ; 2015
    In:  Virulence Vol. 6, No. 6 ( 2015-08-18), p. 581-590
    Details
    In: Virulence, Informa UK Limited, Vol. 6, No. 6 ( 2015-08-18), p. 581-590
    Type of Medium: Online Resource
    ISSN: 2150-5594 , 2150-5608
    URL: Article
    DOI: 10.1080/21505594.2015.1042642
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2015
    detail.hit.zdb_id: 2657572-3
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  • 5
    Online Resource
    Online Resource
    The Multi-Strain Probiotic OMNi-BiOTiC® Active Reduces the Duration of Acute Upper Respiratory Disease in Older People: A Double-Blind, Randomised, Controlled Clinical Trial
    MDPI AG ; 2023
    In:  Microorganisms Vol. 11, No. 7 ( 2023-07-05), p. 1760-
    Details
    In: Microorganisms, MDPI AG, Vol. 11, No. 7 ( 2023-07-05), p. 1760-
    Abstract: Immunosenescence is the adverse change in the human immune function during aging, leaving older people more prone to an increased risk of infections and morbidity. Acute upper respiratory tract infections (URTIs) are very common among older people, often resulting in continued morbidity and mortality. Therefore, approaches, such as consuming probiotics, that shorten the duration or even reduce the incidence of URTIs in older people are being studied. The aim of this study was to determine the effects of a multi-strain probiotic OMNi-BiOTiC® Active, which contains 11 live probiotic strains, on the incidence, duration, and severity of URTIs in older people. In this randomized double-blinded placebo-controlled study, 95 participants, with an average age of 70.9 years in the probiotic group and 69.6 years in the placebo group, were randomly allocated to two groups: 1010 cfu per day of the multi-strain probiotic intervention OMNi-BiOTiC® Active (49) or placebo (46). The incidence of URTIs in older people after 12 weeks supplementation with OMNi-BiOTiC® showed no statistically significant difference between the two groups (p = 0.5244). However, the duration of the URTI infections was statistically significantly different between the groups (p = 0.011). The participants that consumed the probiotic had an average duration of illness of 3.1 ± 1.6 days, whilst participants that received the placebo had symptoms for an average of 6.0 ± 3.8 days (p = 0.011). Statistically significant differences in lymphocyte counts in both groups after supplementation (p = 0.035 for the probiotic group and p = 0.029 for the placebo group) and between both groups were found (p = 0.009). Statistically significant differences in eosinophil (p = 0.002) and basophil counts (p = 0.001) in the probiotic groups before and after supplementation with probiotics were also found. Supplementation with the multi-strain probiotic OMNi-BiOTiC® Active may benefit older people with URTIs. Larger randomised controlled clinical trials are warranted. Clinical Trial Registration; identifier NCT05879393.
    Type of Medium: Online Resource
    ISSN: 2076-2607
    URL: Article
    DOI: 10.3390/microorganisms11071760
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2720891-6
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  • 6
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    Exploring the Feelings of Nurses during Resuscitation—A Cross-Sectional Study
    MDPI AG ; 2021
    In:  Healthcare Vol. 10, No. 1 ( 2021-12-21), p. 5-
    Details
    In: Healthcare, MDPI AG, Vol. 10, No. 1 ( 2021-12-21), p. 5-
    Abstract: Cardiopulmonary resuscitation (CPR) is one of the most stressful situations in emergency medicine. Nurses involved in performing basic and advanced resuscitation procedures are therefore exposed to a certain amount of stress. The purpose of this study was to determine the stressors and the level of stress experienced by nurses during resuscitation. A cross-sectional quantitative study was done. The sample consisted of 457 nurses who worked in emergency units. First demographic data were collected, followed by a questionnaire regarding the effect of different situations that occur during and after resuscitation on nurses including Post-Code Stress Scale questionnaire. The most disturbing situations for respondents were resuscitation of young person (MV = 3.7, SD = 1.4), when they fail to establish an intravenous pathway (MV = 3.5, SD = 1.4), chaotic situation during resuscitation (MV = 3.4, SD = 1.4) and making decision about termination of resuscitation (MV = 3.1, SD = 1.5). Research has shown that nurses are exposed to a certain amount of stress during resuscitation, but most of them manage to compensate for stress effectively.
    Type of Medium: Online Resource
    ISSN: 2227-9032
    URL: Article
    DOI: 10.3390/healthcare10010005
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2721009-1
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  • 7
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    Online Resource
    Alpinia katsumadai Extracts Inhibit Adhesion and Invasion of Campylobacter jejuni in Animal and Human Foetal Small Intestine Cell Lines : Inhibition of Campylobacter Adhesion in Cell Lines
    Wiley ; 2015
    In:  Phytotherapy Research Vol. 29, No. 10 ( 2015-10), p. 1585-1589
    Details
    In: Phytotherapy Research, Wiley, Vol. 29, No. 10 ( 2015-10), p. 1585-1589
    Type of Medium: Online Resource
    ISSN: 0951-418X
    URL: Article
    DOI: 10.1002/ptr.5396
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 1493490-5
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  • 8
    Online Resource
    Online Resource
    Single-Strain Probiotic Lactobacilli for the Treatment of Atopic Dermatitis in Children: A Systematic Review and Meta-Analysis
    MDPI AG ; 2023
    In:  Pharmaceutics Vol. 15, No. 4 ( 2023-04-17), p. 1256-
    Details
    In: Pharmaceutics, MDPI AG, Vol. 15, No. 4 ( 2023-04-17), p. 1256-
    Abstract: Probiotics are known for their positive effects on the gut microbiota. There is growing evidence that the infant gut and skin colonization have a role in the development of the immune system, which may be helpful in the prevention and treatment of atopic dermatitis. This systematic review focused on evaluating the effect of single-strain probiotic lactobacilli consumption on treating children’s atopic dermatitis. Seventeen randomized placebo-controlled trials with the primary outcome of the Scoring Atopic Dermatitis (SCORAD) index were included in the systematic review. Clinical trials using single-strain lactobacilli were included. The search was conducted until October 2022 using PubMed, ScienceDirect, Web of Science, Cochrane library and manual searches. The Joanna Briggs Institute appraisal tool was used to assess the quality of the included studies. Meta-analyses and sub meta-analyses were performed using Cochrane Collaboration methodology. Due to different methods of reporting the SCORAD index, only 14 clinical trials with 1124 children were included in the meta-analysis (574 in the single-strain probiotic lactobacilli group and 550 in the placebo group) and showed that single-strain probiotic lactobacilli statistically significantly reduced the SCORAD index compared to the placebo in children with atopic dermatitis (mean difference [MD]: −4.50; 95% confidence interval [CI] : −7.50 to −1.49; Z = 2.93; p = 0.003; heterogeneity I2 = 90%). The subgroup meta-analysis showed that strains of Limosilactobacillus fermentum were significantly more effective than strains of Lactiplantibacillus plantarum, Lacticaseibacillus paracasei or Lacticaseibacillus rhamnosus. A longer treatment time and younger treatment age statistically significantly reduced symptoms of atopic dermatitis. The result of this systematic review and meta-analysis shows that certain single-strain probiotic lactobacilli are more successful than others in reducing atopic dermatitis severity in children. Therefore, careful consideration to strain selection, treatment time and the age of the treated patients are important factors in enhancing the effectiveness of reducing atopic dermatitis in children when choosing probiotic single-strain lactobacilli.
    Type of Medium: Online Resource
    ISSN: 1999-4923
    URL: Article
    DOI: 10.3390/pharmaceutics15041256
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2527217-2
    SSG: 15,3
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  • 9
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    Online Resource
    The influence of dietary compounds on gut microbiota
    Slovenian Medical Association ; 2021
    In:  Slovenian Medical Journal Vol. 90, No. 3-4 ( 2021-03-06), p. 178-192
    Details
    In: Slovenian Medical Journal, Slovenian Medical Association, Vol. 90, No. 3-4 ( 2021-03-06), p. 178-192
    Abstract: The gut microbiota is a complex community composed of trillions of microbes that adapts to its host over the lifetime. Recently, the advances of the methods of high-throughput sequencing have allowed the identification of microbial species in a stool sample, and mass spectrometry identification of their metabolites, both of which together have enabled much of the relevant research in the field. It has became evident that gut microbiota plays an important role in human health and influences the risk of developing many chronic diseases, including obesity, inflammatory bowel disease, type 2 diabetes, cardiovascular disease, and cancer. The diverse ecosystem of the gut includes bacteria, viruses, phages, yeasts, archaea, fungi and protozoa. They are responsible for the production of bioactive metabolites, regulation of immune function, energy homeostasis and protection against pathogens. The mentioned functions are dependent on the diversity and abundance of the microbiota which is the reflection of the dietary habits and genetics of the host among other factors. As such, gut microbiota has significant interindividual variations. Diet and lifestyle changes present important determinants in microbiota shaping. The use of antibiotics, different sanitation measures, consumption of processed food and different diets are also reflected in the shifts of gut microbiota composition. Some of the dramatic dietary alterations can cause changes in gut microbiota composition already within 24 h and some of these changes may be difficult to reverse. Through modulation of gut microbiota composition, diet could offer a potential to manage the risk of developing disease and at the same time improving the quality of life and longevity. In this review we look at the role of diet, and specific dietary components, namely carbohydrates, proteins, fats and polyphenols on gut microbiota composition.
    Type of Medium: Online Resource
    ISSN: 1581-0224 , 1318-0347
    URL: Article
    DOI: 10.6016/ZdravVestn.3005
    Language: Unknown
    Publisher: Slovenian Medical Association
    Publication Date: 2021
    detail.hit.zdb_id: 2502309-3
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  • 10
    Online Resource
    Online Resource
    Knowledge of fermentation and health benefits among general population in North-eastern Slovenia
    Springer Science and Business Media LLC ; 2022
    In:  BMC Public Health Vol. 22, No. 1 ( 2022-09-07)
    Details
    In: BMC Public Health, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-09-07)
    Abstract: Fermented foods are staples of the human diet and fermentation process has been used by humans for thousands of years. The preparation of fermented foods was performed in the past without knowledge of the role of microorganisms involved. Nowadays, fermented foods, due to their proclaimed health benefits for consumers, are becoming increasingly popular. Our study was constructed to provide data on awareness and use of fermented foods among people in North-eastern Slovenia. Methods The cross-sectional study included 349 individuals (16–89 years of age). An online survey was designed to assess the participants' knowledge of fermentation, fermented foods, the consumption of fermented foods and awareness of the health benefits. Data were collected from March to June 2021 and analyzed using IBM SPSS 27.0. Results Compared with the youngest participants ( 〈  21 years) knowledge of fermentation was higher in older individuals ( p   〈  0.001). More than a half of the participants recognized the role of lactic acid bacteria and yeasts in fermentation process, however, only 18.3% of participants were aware of the role of the molds. Only 25.9% of the participants have become acquainted with fermented foods at home and 62.2% of them were aware of health benefits of fermented foods, but mostly on gastrointestinal health and the immune system. Conclusions As people today live predominantly in urban areas and incline towards westernized foods, they often lack the knowledge of fermentation and awareness regarding the nutritional value of fermented foods and their preparation. Steps should be taken to educate younger generations regarding the health benefits of fermented foods especially considering that most of them expressed their interest in learning more about the process.
    Type of Medium: Online Resource
    ISSN: 1471-2458
    URL: Article
    DOI: 10.1186/s12889-022-14094-9
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2041338-5
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