In:
Uludağ Üniversitesi Tıp Fakültesi Dergisi, Uludag Universitesi Tip Fakultesi Dergisi, Vol. 48, No. 1 ( 2022-04-01), p. 37-41
Abstract:
Endometrial cancer (EC) is the most common gynecological malignancy in developed countries. Obesity is known as the major risk factor for endometrial cancer. The most common subtype of endometrial cancer is endometrioid endometrial carcinoma (EEC). Our study aims to investigate the demographic and clinicopathological characteristics of metastatic EEC patients and the effect of treatments on survival. The median age of the patients was 58 (39.4-81.9) years. Sixteen patients presented with abnormal vaginal bleeding. The median follow-up time was 43 (0.2-104.3) months. The median progression-free survival (PFS) was 39.9 months (95% confidence interval (CI): 35.0-79.1), and the median overall survival (OS) was 59.1 months (95% CI: 39.1-80.8). Patients receiving chemoradiotherapy had significantly longer PFS and OS than patients treated with chemotherapy alone (log-rank test, p=0.012 for PFS, p=0.015 for OS). Our study supports that chemoradiotherapy might be a treatment option for selected patient groups in the metastatic stage.
Type of Medium:
Online Resource
ISSN:
1300-414X
DOI:
10.32708/uutfd.1028896
Language:
Unknown
Publisher:
Uludag Universitesi Tip Fakultesi Dergisi
Publication Date:
2022
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