In:
Frontiers in Oncology, Frontiers Media SA, Vol. 12 ( 2022-3-18)
Kurzfassung:
The aim of the study was to evaluate the computed diffusion-weighted images (DWI) in image quality and diagnostic performance of rectal cancer by comparing with the acquired DWI. Methods A total of 103 consecutive patients with primary rectal cancer were enrolled in this study. All patients underwent two DWI sequences, namely, conventional acquisition with b = 0 and 1,000 s/mm 2 (aDWI b1,000 ) and another with b = 0 and 700 s/mm 2 on a 3.0T MR scanner (MAGNETOM Prisma; Siemens Healthcare, Germany). The images (b = 0 and 700 s/mm 2 ) were used to compute the diffusion images with b value of 1,000 s/mm 2 (cDWI b1,000 ). Qualitative and quantitative analysis of both computed and acquired DWI images was performed, namely, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and signal intensity ratio (SIR), and also diagnostic staging performance. Interclass correlation coefficients, weighted κ coefficient, Friedman test, Wilcoxon paired test, and McNemar or Fisher test were used for repeatability and comparison assessment. Results Compared with the aDWI b1,000 images, the cDWI b1,000 ones exhibited significant higher scores of subjective image quality (all P & lt;0.050). SNR, SIR, and CNR of the cDWI b1,000 images were superior to those of the aDWI b1,000 ones (P & lt;0.001). The overall diagnostic accuracy of computed images was higher than that of the aDWI b1,000 images in T stage (P & lt;0.001), with markedly better sensitivity and specificity in distinguishing T1–2 tumors from the T3–4 ones (P & lt;0.050). Conclusion cDWI b1,000 images from lower b values might be a useful alternative option and comparable to the acquired DWI, providing better image quality and diagnostic performance in preoperative rectal cancer staging.
Materialart:
Online-Ressource
ISSN:
2234-943X
DOI:
10.3389/fonc.2022.788731
Sprache:
Unbekannt
Verlag:
Frontiers Media SA
Publikationsdatum:
2022
ZDB Id:
2649216-7
Permalink