In:
PLOS ONE, Public Library of Science (PLoS), Vol. 18, No. 5 ( 2023-5-11), p. e0284142-
Kurzfassung:
To explore the interior of a lesion in a 3D endoluminal view, this study investigates the application of an ‘electronic biopsy’ (EB) technique to computed tomographic colonography (CTC) for further differentiation and 2D image correlation of endoluminal lesions in the air spaces. A retrospective study of sixty-two various endoluminal lesions from thirty patients (13 males, 17 females; age range, 31 to 90 years) was approved by our institutional review board and evaluated. The endoluminal lesions were segmented using gray-level threshold and reconstructed into isosurfaces using a marching cube algorithm. EB allows users to interactively erode and apply grey-level mapping (GM) to the surface of the region of interest (ROI) in 3D CTC. Radiologists conducted the clinical evaluation, and the resulting data were analyzed. EB significantly improves 3D gray-level presentation for evaluating the surface and inside of endoluminal lesions over that of SR, GM or target GM (TGM) (P 〈 0.01) with preservation of the 3D spatial effect. Moreover, 3D to 2D image correlation were achieved in any layer of the lesion using EB as did GM/TGM on the surface. The specificity and diagnostic accuracy of EB are significantly greater than those of SR (P 〈 0.01). These performance can be better further with GM/TGM and reach the best with EB (specificity, 89.3–92.9%; accuracy, 95.2–96.8%). EB can be used in CTC to improve the differentiation of endoluminal lesions. EB increases 3D to 2D image correlations of the lesions on or beneath the lesion surface.
Materialart:
Online-Ressource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0284142
DOI:
10.1371/journal.pone.0284142.g001
DOI:
10.1371/journal.pone.0284142.g002
DOI:
10.1371/journal.pone.0284142.g003
DOI:
10.1371/journal.pone.0284142.g004
DOI:
10.1371/journal.pone.0284142.g005
DOI:
10.1371/journal.pone.0284142.g006
DOI:
10.1371/journal.pone.0284142.g007
DOI:
10.1371/journal.pone.0284142.t001
DOI:
10.1371/journal.pone.0284142.t002
DOI:
10.1371/journal.pone.0284142.s001
DOI:
10.1371/journal.pone.0284142.s002
DOI:
10.1371/journal.pone.0284142.r001
DOI:
10.1371/journal.pone.0284142.r002
DOI:
10.1371/journal.pone.0284142.r003
DOI:
10.1371/journal.pone.0284142.r004
DOI:
10.1371/journal.pone.0284142.r005
Sprache:
Englisch
Verlag:
Public Library of Science (PLoS)
Publikationsdatum:
2023
ZDB Id:
2267670-3
Permalink