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  • 1
    Online Resource
    Online Resource
    San Diego :Elsevier,
    Keywords: Space environment. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (334 pages)
    Edition: 1st ed.
    ISBN: 9780128155721
    DDC: 538.766
    Language: English
    Note: Cover -- Title -- Copyright -- Contents -- Contributors -- Preface -- Chapter 1 - Introduction and historical background -- 1.1 - Historical overview -- 1.2 - Relation to solar wind drivers -- 1.3 - Space weather effects -- 1.4 - Book content -- Acknowledgments -- References -- Chapter 2 - Observations and measurement techniques -- 2.1 - Early ring-current measurements -- 2.1.1 - Ring current energy density -- 2.1.2 - Ring current ion spectra -- 2.2 - Ring current composition and the source of the ring current -- 2.2.1 - Low-energy measurements -- 2.2.2 - The "bulk" of the ring current -- 2.2.2.1 - Storm-time energy density -- 2.2.2.2 - The role of the solar wind source -- 2.2.2.3 - Signatures of transport/loss in Ion spectra -- 2.2.2.4 - Statistical models, including quiet time observations -- 2.3 - Imaging the ring current -- 2.4 - Multispacecraft measurements and recent results -- 2.4.1 - The Cluster mission -- 2.4.2 - Van Allen Probes and Arase -- 2.4.2.1 - Ring current development -- 2.4.2.2 - Low L-shell heavy ion features -- 2.4.2.3 - Statistical studies of the ring current -- 2.5 - Summary -- References -- Chapter 3 - Theoretical description -- 3.1 - Motivation -- 3.2 - Single particle motion in electromagnetic fields -- 3.2.1 - Maxwell's equations -- 3.2.2 - The Lorentz force -- 3.2.3 - Particle motion in a uniform magnetic field -- 3.2.4 - Particle motion in nonuniform magnetic field -- 3.2.5 - Magnetic mirroring -- 3.2.6 - Gradient-curvature drift -- 3.3 - Adiabatic invariants -- 3.4 - Statistical description: elements of kinetic theory -- 3.4.1 - The Boltzmann equation -- 3.4.2 - Macroscopic variables as moments of the distribution function -- 3.5 - Motion in a nonuniform magnetic field -- 3.6 - Bounce averaged drifts -- 3.6.1 - Bounce-averaged particle drifts -- 3.6.2 - Bounce-averaged drifts in arbitrary magnetic fields. , 3.6.3 - Magnetospheric electric field -- 3.7 - Losses -- 3.7.1 - Charge exchange -- 3.7.2 - The role of charge exchange in the loss of ring current ions -- 3.7.3 - Coulomb collisions -- 3.7.4 - Scattering via wave particle interactions -- 3.7.4.1 - Minimum resonant energy -- 3.7.5 - Wave properties in hot plasma -- 3.7.5.1 - Quasi-linear diffusion coefficients -- 3.7.6 - Convective loss -- 3.8 - Conclusions -- Appendix A. Equatorial gyro-frequency -- Appendix B. Equatorial gyro-radius -- Appendix C. Bounce period -- References -- Chapter 4 - Modeling techniques -- 4.1 - Introduction -- 4.2 - Empirical models -- 4.2.1 - Low-dimensional models -- 4.2.2 - Ion and electron flux models -- 4.2.3 - Electric field models -- 4.2.4 - Magnetic field models -- 4.2.4.1 - The internal magnetic field -- 4.2.4.2 - Modeling the external magnetic field -- 4.3 - Theoretical models -- 4.3.1 - Introduction -- 4.3.2 - The Rice Convection Model -- 4.3.3 - The MSM and MSFM -- 4.3.4 - The RCM-Equilibrium (RCM-E) -- 4.3.5 - RCM-Jupiter/Saturn -- 4.3.6 - Fontaine, Senior, Blanc, and Peymirat convection model -- 4.3.7 - The Chen ring current model -- 4.3.8 - The Fok ring current and the comprehensive ring current model (CRCM) models -- 4.3.9 - The ring current-atmosphere interactions model (RAM) -- 4.3.10 - The ring current-atmosphere interactions model with self-consistent magnetic field (RAM-SCB) -- 4.3.11 - HEIDI -- 4.3.12 - GEMSIS -- 4.3.13 - Coupled global MHD models -- 4.3.14 - Data assimilation models -- 4.3.15 - Particle tracing algorithms -- 4.4 - Discussion and summary -- Acknowledgments -- References -- Chapter 5 - Ring current development -- 5.1 - Introduction -- 5.2 - Ring current sources -- 5.2.1 - Plasma sheet -- 5.2.2 - Direct ionosphere to ring current plasma transfer? -- 5.3 - Ring current particle transport: convective and diffusive. , 5.4 - Effect of plasma sheet variations on ring current intensity -- 5.5 - Effects of magnetic self-consistency -- 5.6 - Model-data comparisons of ring current development -- 5.7 - Challenges for future understanding of ring current development -- Acknowledgments -- References -- Chapter 6 - Ring current decay -- 6.1 - Introduction -- 6.2 - Charge exchange -- 6.3 - Coulomb collisions -- 6.4 - Precipitation losses -- 6.4.1 - Observations of particle precipitation -- 6.4.2 - Wave-particle interactions -- 6.4.3 - Field line curvature scattering -- 6.4.4 - Other mechanisms -- 6.5 - Magnetopause losses -- 6.6 - Discussion and conclusions -- Acknowledgments -- References -- Chapter 7 - Cross-regional coupling -- 7.1 - Roles of ring current in magnetosphere-ionosphere coupling -- 7.2 - Magnetic effects of the ring current -- 7.3 - Ring current velocity anisotropy and plasma wave growths -- 7.4 - Electric coupling between the ring current and ionosphere -- 7.5 - Ring current moderation with the ionospheric conductivity -- 7.6 - Final remark -- Acknowledgment -- References -- Chapter 8 - Space weather effects and prediction -- 8.1 - Effects of space weather -- 8.2 - Spacecraft charging and electrostatic discharges -- 8.2.1 - Surface charging -- 8.2.2 - Worst-case charging environments and spacecraft design -- 8.2.3 - Frame charging and differential charging -- 8.2.4 - Internal charging -- 8.2.5 - Internal charging models -- 8.2.6 - Space environment models and charging analyses -- 8.3 - Geomagnetically induced currents -- 8.4 - Conclusions -- Acknowledgments -- References -- Chapter 9 - Comparative planetary ring currents -- 9.1 - Comparing planetary magnetospheres -- 9.1.1 - Solar wind versus rotation -- 9.1.2 - Neutral materials -- 9.1.2.1 - Satellites -- 9.1.2.2 - Gas, dust, and plasmas from satellites. , 9.1.2.3 - Calculating losses from passive satellites -- 9.2 - How does a rotationally driven magnetosphere operate? -- 9.3 - Comparing ring current populations -- 9.3.1 - Kennel-Petschek theory -- 9.3.2 - Limiting spectra at the target planets -- 9.4 - Ring current population dynamics and sources -- 9.5 - Ring current population losses -- 9.6 - Uranus (and Neptune) -- 9.7 - Discussion -- 9.8 - Appendix -- References -- APPENDIX 1 - Frequently Used Abbreviations -- APPENDIX 2 - Useful Websites and Download Links -- APPENDIX 3 - Illustrative Movies and Other Materials -- References -- Index -- Back cover.
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  • 2
    Publication Date: 2023-10-21
    Description: European coasts face multiple, interacting and cumulative pressures including those resulting from increasing greenhouse gas emissions (e.g. sea-level rise, Ocean warming, Ocean acidification, extreme events) and localised activities such as fishing, aquaculture, waste disposal and coastal urbanisation. These create a unique set of context-specific issues that need to be addressed holistically using a systems approach, considering the dynamics between both coastal societies and ecosystems as part of interconnected social-ecological systems. EMB Position Paper No. 27 ‘Building Coastal Resilience in Europe’ presents key policy and scientific recommendations on how to build coastal resilience and enhance capacity to cope with impacts from climate change and other coastal pressures.
    Description: Published
    Description: Refereed
    Keywords: Greenhouse gas ; Climate change effects ; Coastal resilience
    Repository Name: AquaDocs
    Type: Book/Monograph/Conference Proceedings
    Format: 128pp.
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  • 3
    ISSN: 1574-695X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The recognition of a pathogen or a vaccine antigen formulation by cells in the innate immune system leads to production of proinflammatory cytokines, which will determine the ensuing acquired immune response quantitatively and qualitatively. Tumour necrosis factor (TNF)-α, interleukin (IL)-1 and IL-6 are the first set of cytokines produced upon such an encounter, which have roles both in protective immunity and immunopathogenesis evident with respiratory syncytial virus (RSV). RSV antigens in different physical adjuvant-vaccine formulations were analysed for their capacity to provoke cultured murine peritoneal cells to produce these three proinflammatory cytokines. RSV immunostimulating complex (ISCOM), i.e. both antigen and adjuvant are incorporated in the same particle, induced high levels of IL-1α being of the same magnitude or higher than those of live RSV and lipopolysaccharide (LPS). Live virus and LPS induced higher levels of IL-6 and TNF-α than ISCOM and so did non-adjuvanted UV-inactivated RSV but only at high doses. ISCOM-Matrix, i.e. ISCOM without antigens, admixed as a separate entity to inactivated RSV, downregulated or blocked the cytokine response to the inactivated RSV in contrast to ISCOM. Kinetic studies showed that ISCOM induced cytokine production first detected at hours 1, 2, 4 for TNF-α, IL-6 and IL-1α respectively, which was earlier than for the other antigen formulations containing corresponding doses of antigen and/or Quillaja adjuvant. Peak values for production of TNF-α and IL-6 were at 8 h and for IL-1α at 72 h following stimulation with ISCOM. The delayed appearance of IL-1α may reflect the cell-bound nature of this cytokine.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1574-695X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: A successful vaccine against human RSV (HRSV) is likely to induce a Th1 or a balanced Th1/TH2 cytokine response. We tested a panel of HRSV immunostimulating complexes (ISCOMs) containing different Quillaja saponin fractions (QH-A, QH-C, and 703: a mixture of 70% QH-A and 30% QH-C) with different immunological properties for their capacity of inducing innate and acquired immune responses. The HRSV 703 ISCOMs induced the strongest innate and acquired immune responses, followed by RSV QH-C and QH-A ISCOMs. All three formulations induced various degrees of Th1 bias response with prominent production of IFN-γ being 10–50 times higher than that of IL-4 and IL-5. The HRSV specific IgG isotype profile correlated with the predominant secretion of Th1 cytokines, with strong induction of IgG2a antibodies. The 703 ISCOMs induced the most pronounced Th1 profile followed by QH-C and QH-A ISCOMs. The high incorporation of F protein in these ISCOMs compared to G protein combined with the Th1 biased nature of ISCOM are likely to be the causes to promote a Th1 type of profile. The prospect to formulate an RSV ISCOM formulation with an optimal Th1/Th2 balance is in reach particularly in view of the versatile properties of the ISCOM concept.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Cross-presentation of cell-associated antigens plays an important role in regulating CD8+ T cell responses to proteins that are not expressed by antigen-presenting cells (APCs). Dendritic cells are the principal cross-presenting APCs in vivo and much progress has been made ...
    Type of Medium: Electronic Resource
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  • 6
    Publication Date: 2016-09-03
    Description: Journal of the American Chemical Society DOI: 10.1021/jacs.6b06994
    Print ISSN: 0002-7863
    Electronic ISSN: 1520-5126
    Topics: Chemistry and Pharmacology
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  • 7
    Publication Date: 2013-01-25
    Description: Author(s): Pice Chen, Margaret P. Cosgriff, Qingteng Zhang, Sara J. Callori, Bernhard W. Adams, Eric M. Dufresne, Matthew Dawber, and Paul G. Evans The remnant polarization of weakly coupled ferroelectric-dielectric superlattices is distributed unequally between the component layers, and as a result the components respond differently to applied electric fields. The difference is apparent in both the nanometer-scale structure of striped polariza... [Phys. Rev. Lett. 110, 047601] Published Thu Jan 24, 2013
    Keywords: Condensed Matter: Electronic Properties, etc.
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
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  • 8
    Publication Date: 2018-01-07
    Description: Journal of Medicinal Chemistry DOI: 10.1021/acs.jmedchem.7b01654
    Topics: Chemistry and Pharmacology
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  • 9
    Publication Date: 2013-01-19
    Description: Author(s): Haidan Wen, Pice Chen, Margaret P. Cosgriff, Donald A. Walko, June Hyuk Lee, Carolina Adamo, Richard D. Schaller, Jon F. Ihlefeld, Eric M. Dufresne, Darrell G. Schlom, Paul G. Evans, John W. Freeland, and Yuelin Li Above-band-gap optical excitation produces interdependent structural and electronic responses in a multiferroic BiFeO 3 thin film. Time-resolved synchrotron x-ray diffraction shows that photoexcitation can induce a large out-of-plane strain, with magnitudes on the order of half of one percent followi... [Phys. Rev. Lett. 110, 037601] Published Fri Jan 18, 2013
    Keywords: Condensed Matter: Electronic Properties, etc.
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
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  • 10
    Publication Date: 2017-04-19
    Description: Corrigendum: The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies Nature Communications, Published online: 18 April 2017; doi:10.1038/ncomms15350
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
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