Keywords:
Neuroendocrinology.
;
Electronic books.
Type of Medium:
Online Resource
Pages:
1 online resource (470 pages)
Edition:
1st ed.
ISBN:
9781536109290
Series Statement:
Endocrinology Research and Clinical Developments
URL:
https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=4871577
DDC:
612.79999999999995
Language:
English
Note:
Intro -- Contents -- Preface -- Hyperprolactinemia and Cushing's Disease: Occam's Razor vs Hickam's Dictum -- Introduction -- Case Presentation -- Clinical Diagnosis -- Treatment -- Follow up -- Discussion -- References -- Langerhans Cell Histiocytosis: Pathophysiology, Diagnosis, and Management -- 1Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, UK -- 2Department of Endocrinology, Portuguese Institute of Oncology, Portugal -- Case Description -- Discussion -- Pathophysiology and Epidemiology -- Diagnosis and Initial Evaluation -- Endocrine Abnormalities: Diagnosis and Management -- Management Approach -- Follow-Up and Prognosis -- Acknowledgments -- References -- A Patient Presenting with Headache and Epistaxis -- Case Presentation -- Discussion -- References -- A Rare Presentation of TSH Secreting Pituitary Macroadenoma with Coexisting Primary Hypothyroidism from Hashimoto's Thyroiditis -- Abstract -- Introduction -- Case Report -- Discussion -- Conclusion -- References -- Management of Osteoporosis in a Man with Cushing's Disease and Hypogonadotrophic Hypogonadism Following Successful Transsphenoidal Surgery -- Abbreviations -- 1. What Is the Current Evidence Regarding the Screening and Treatment of Osteoporosis Induced by Cushing's Disease? Can the Corresponding Literature in Patients with Exogenous Glucocorticoid-Induced Osteoporosis (GIO) Be Utilized in Cushing's Disease? -- 2. What Are the Mechanisms of Bone Loss in Patients with Hypercortisolism? -- 3. What Is the Extent (and the Trajectory) of Bone Recovery in This Patient with Evidence of Cured Cushing's Disease? What Is the Likelihood of Complete Bone Recovery to Baseline?.
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4. When Should Antiresorptive Therapy Be Considered in This Patient? What Therapeutic Agents Should Be Considered as First Line Therapy? -- 5. How Much Bone Recovery Is Expected from Androgen Replacement Therapy? Should Antiresorptive Therapy be Postponed in Anticipation of Potential Skeletal Gains from Androgen Replacement? -- 6. What Anatomic Fractures Is This Patient at Highest Risk of Developing? How Does the Patient's Gender Affect the Phenotype and Severity of Bone Disease? -- References -- Multidisciplinary Management of Atypical Pituitary Adenomas -- Case Report -- The History of Atypical Adenomas -- Discussion -- Treatment Recommendations -- Gross Total Resection -- Residual Disease -- Recurrence or Growth of Residual Disease -- Repeat Recurrence or Inaccessibility of Tumor -- Conclusion -- References -- A Referral for Delayed Puberty May Unveil an Underlying Complex Syndrome -- Acknowledgments -- References -- Management of Cystic Prolactinomas -- Introduction -- Case #1 -- Case #2 -- Case #3 -- Discussion -- References -- Primary Generalized Glucocorticoid Resistance Syndrome -- Abstract -- Clinical Vignette -- Pathophysiology -- Molecular Mechanism -- Clinical Presentation and Differential Diagnosis -- Patients Evaluation and Management -- References -- Management of Persistent Disease after Surgery in a Young Woman with Acromegaly -- Case Presentation -- Management of the Patient with Persistent Disease Following Surgery for Acromegaly -- Further Treatment Plan -- Medical Therapy -- Combination Medical Therapy -- Cabergoline and Pegvisomant -- Somatostatin Receptor Ligands and Pegvisomant -- Pregnancy in Acromegaly -- Clinical Course Following Pregnancy -- Key Points -- References -- Cushing's Syndrome: What Should We Do While Investigating for the Source? -- Case Presentation -- Initial Presentation -- How Was a Diagnosis Made?.
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Screening Testing -- Confirmatory Testing -- Localization Studies -- Treatment -- Co-Morbidities Associated with CS -- Clinical Course on Medical Treatment -- Key Points -- References -- Challenges in the Management of Ectopic Cushing's Syndrome -- Medical Management -- Etomidate -- Metyrapone -- Ketoconazole -- Somatostatin Analogs -- Mifepristone -- Cabergoline -- Mitotane -- Aminoglutethimide -- LCI699 -- Hypercoagulability in Cushing's Syndrome -- Risk of Opportunistic Infections -- Cyclic Cushing's Syndrome -- Conclusion -- References -- A Case of Gigantism -- Management and Discussion -- Summary -- References -- Pituitary Stalk Lesions: Challenges in Diagnosis -- Case Presentation -- Discussion -- References -- When Cushing's Comes and Goes … -- Blood Tests -- 24 Hour Urinary Cortisol -- Midnight Cortisol -- Low Dose Dexamethasone Suppression Test -- Hunan-Sequence Corticotrophin Releasing Hormone (CRH) Stimulation Test -- Radiology -- Interpretation of Results -- Change in ACTH Levels around the Time of Thymectomy -- Case Discussion -- References -- Hyponatremia after Pituitary Surgery: SIADH or Cerebral Salt Wasting? -- Introduction -- Case Presentation -- Triphasic Response -- Isolated Second Phase -- SIADH versus CSW -- Other Endocrinopathies Causing Hyponatremia -- Acute versus Chronic Hyponatremia -- Treatment of Hyponatremia -- Summary -- References -- Cushing's Disease Identified Post-Adrenalectomy for Adrenal Nodules -- Introduction -- Case 1 -- Comments - Case 1 -- Case 2 -- Background -- Case Presentation -- Evaluation -- Comments - Case 2 -- Summary Comments: Cases 1 and 2 -- Conclusion -- Acknowledgments -- References -- Cushing's Syndrome: You Have to Dot the "I's" and Cross the "T's" -- References -- Headaches in a Patient with a Pituitary Mass -- Introduction -- Case Presentation -- Watchful Waiting -- Back to the Case.
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Etiology and Diagnostic Evaluation of Hypophysitis -- Back to the Case -- Glucocorticoids Role in Management of Primary Hypophysitis -- Role of Surgical Intervention -- Miscellaneous Therapies -- Conclusion -- References -- Cushing Syndrome in MEN-1: A Rare Association and a Challenging Diagnosis -- Case Report -- Is It Correct to Perform Biochemical Evaluation for CS in Incidentally Discovered Adrenal Masses? -- Case Report/Continuation -- Is It Correct to Suspect Type 1 Multiple Endocrine Neoplasia (MEN-1) Syndrome in This Patient? -- Cushing Syndrome in MEN-1 -- How Can the Cause of Cushing Syndrome in This Patient Be Established? -- Case Report/Further Work Up -- Final Remarks -- References -- A Medically Complicated Case of Acromegaly with Challenging Decision Making -- History of Present Illness -- Physical Examination -- Medications -- Lab Results -- Radiological Imaging -- Summary of Patient Management and Decision Making -- Discussion for our Treatment Plan -- Acromegaly and Associated Co-Morbidities -- Conclusion -- References -- Effects of Testosterone Replacement on Prolactinoma Management -- References -- Management of an Aggressive Silent Corticotroph Adenoma -- References -- Pregnancy in Women with Hypopituitarism and Growth Hormone Substitution Therapy -- Clinical Presentation -- Conclusion -- References -- Treatment of Aggressive Prolactin-Secreting Pituitary Adenomas with Adjuvant Temozolomide Chemotherapy -- Abstract -- Introduction -- Case Report -- Discussion -- Conclusion -- References -- A Suprasellar Mass of Unclear Etiology Presenting at a Time of Concurrent Metastatic Carcinoma Diagnosis -- References -- Management of Acromegaly in a Patient with McCune Albright Syndrome -- Discussion -- References -- Nondiagnostic Inferior Petrosal Sinus Sampling in Suspected Cushing Disease -- Introduction -- Case #1 -- Evaluation.
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Treatment and Outcome -- Case #2 -- Evaluation -- Treatment and Outcome -- Discussion -- References -- Recurrent Hyponatremia with Normal Cosyntropin Stimulation: Don't Ignore Secondary Adrenal Insufficiency -- Introduction -- Case Presentation -- Evaluation of the Hypothalamic-Pituitary Adrenal Axis -- Morning Cortisol Levels -- Cosyntropin Stimulation Test -- Insulin Tolerance Test -- Metyrapone Stimulation Test -- Electrolyte Abnormalities in AI -- Case Discussion -- Conclusion -- References -- Pituitary Adenoma and Other Considerations -- Case Presentation -- Hormonal Evaluation -- MRI -- References -- Diagnosis and Treatment of an ACTH-Secreting Ectopic Pituitary Adenoma in the Sphenoid Sinus -- Introduction -- Case Description -- Discussion -- Challenges of Diagnosis -- Clinical Decision-Making Explained -- Postoperative Management -- Conclusion and Lessons -- References -- Microsurgical Transsphenoidal Chiasmapexy for Empty Sella Syndrome and Traction Chiasmopathy -- Introduction -- Case Illustration -- History and Examination -- Laboratory Studies -- Clinical and Operative Plan -- Operative Technique -- Discussion -- References -- Cystic Prolactinomas-Management Considerations -- Abstract -- Introduction -- Discussion -- Conclusions/Author's Perspective -- References -- Striving for the Best Possible Quality of Life in a Complex Cushing's Patient: Cure or Control? -- Case Description -- Considerations of the Multidisciplinary Team on Initial Diagnosis and Management -- Diagnosis of Hypercortisolism in This Patient -- Diagnosis of Pituitary Source of ACTH Dependent Cushing -- Rationale for Medical Pre-Treatment in General -- Consideration for First Surgical Exploration in This Individual Patient -- Considerations of the Multidisciplinary Team on Secondary Management -- Treatment Options -- Transnasal Surgery.
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Alternative Neurosurgical Options.
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