Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
British journal of dermatology
80 (1968), S. 0
ISSN:
1365-2133
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
SUMMARY. Delayed pressure urticaria in 15 patients has been investigated. It is characterized by the development of deep painful swelling 4–6 hours after pressure has been applied to the skin. It is sometitnes accompanied by systemic manifestations such as a leucocytosis and rigors.Delayed pressure urticaria is unaffected by antihistamines but it is controlled by steroids.The injection into the skin of saline and various pharmacological agents also causes delayed wealing. Prior treatment of the skin with 48/80 prevents the reaction.Immunofluorescent studies showed that the affected tissues contained no excess fibrinogen, immunoglobulins or complement.It is suggested that delayed pressure urticaria is related to delayed dermographism and may be due to a disorder of kinin activity.The timing and depth of the changes in vascular permeability characteristic of urticaria can be correlated. They are influenced by many mediators and by the pattern of the vasculature of the skin. A change in the timing or depth of the urticaria is the most that should be expected from the use of a single pharmacological agent in the treatment of urticaria.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2133.1968.tb12334.x
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