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  • 11
    ISSN: 1432-1238
    Keywords: Key words Alcoholism ; Trauma ; Intensive care unit ; Complications ; Infection ; Alcohol withdrawal syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract   Objective: A chronic alcoholic group following trauma was investigated to determine whether their ICU stay was longer than that of a non-alcoholic group and whether their intercurrent complication rate was increased. Design: Prospective study. Setting: An intensive care unit. Patients: A total of 102 polytraumatized patients were transferred to the ICU after admission to the emergency room and after surgical treatment. Of these patients 69 were chronic alcoholics and 33 were allocated to the non-alcoholic group. The chronic-alcoholic group met the DSM-III-R and ICD-10 criteria for alcohol dependence or chronic alcohol abuse/harmful use. The daily ethanol intake in these patients was ≥60 g. Diagnostic indicators included an alcoholism-related questionnaire (CAGE), conventional laboratory markers and carbohydrate-deficient transferrin. Measurement and results: Major intercurrent complications such as alcohol withdrawal syndrome (AWS), pneumonia, cardiac complications and bleeding disorders were documented and defined according to internationally accepted criteria. Patients did not differ significantly between groups regarding age, TRISS and APACHE score on admission. The rate of major intercurrent complications was 196% in the chronic alcoholic vs 70% in the non-alcoholic group (P=0.0001). Because of the increased intercurrent complication rate, the ICU stay was significantly prolonged in the chronic-alcoholic group by a median period of 9 days. Conclusions: Chronic alcoholics are reported to have an increased risk of morbidity and mortality. However, to our knowledge, nothing is known about the morbidity and mortality of chronic alcoholics in intensive care units following trauma. Since chronic alcoholics in the ICU develop more major complications with a significantly prolonged ICU stay following trauma than non-alcoholics, it seems reasonable to intensify research to identify chronic alcoholics and to prevent alcohol-related complications.
    Type of Medium: Electronic Resource
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  • 12
    ISSN: 1432-1238
    Keywords: Alcoholism ; Trauma ; Intensive care unit ; Complications ; Infection ; Alcohol withdrawal syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective A chronic alcoholic group following trauma was investigated to determine whether their ICU stay was longer than that of a non-alcoholic group and whether their intercurrent complication rate was increased Design Prospective study. Setting An intensive care unit. Patients A total of 102 polytraumatized patients were transferred to the ICU after admission to the emergency room and after surgical treatment. Of these patients 69 were chronic alcoholics and 33 were allocated to the non-alcoholic group. The chronic-alcoholic group met the DSM-III-R and ICD-10 criteria for alcohol dependence or chronic alcohol abuse/harmful use. The daily ethanol intake in these patients was ≥60 g. Diagnostic indicators included an alcoholismrelated questionnaire (CAGE), conventional laboratory markers and carbohydrate-deficient transferrin. Measurement and results Major intercurrent complications such as alcohol withdrawal syndrome (AWS), pneumonia, cardiac complications and bleeding disorders were documented and defined according to internationally accepted criteria. Patients did not differ significantly between groups regarding age, TRISS and APACHE score on admission. The rate of major intercurrent complications was 196% in the chronic alcoholic vs 70% in the non-alcoholic group (P=0.0001). Because of the increased intercurrent complication rate, the ICU stay was significantly prolonged in the chronic-alcoholic group by a median period of 9 days. Conclusions Chronic alcoholics are reported to have an increased risk of morbidity and mortality. However, to our knowledge, nothing is known about the morbidity and mortality of chronic alcoholics in intensive care units following trauma. Since chronic alcoholics in the ICU develop mor major complications with a significantly prolonged ICU stay following trauma than non-alcoholics, it seems reasonable to intensify research to identify chronic alcoholics and to prevent alcohol-related complications.
    Type of Medium: Electronic Resource
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  • 13
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Journal of clinical monitoring and computing 5 (1989), S. 287-287 
    ISSN: 1573-2614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Medicine
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 194 (1930), S. 299-304 
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wurden auf Grund der eingangs diskutierten theoretischen Überlegungen Versuche zur Trennung der Bromisotopen durch fraktionierte Sublimation angestellt, wobei drei Sublimationsstufen von den Temperaturen -18,5°, -25°, -36° Verwendung fanden. Die absublimierte, leichtest flüchtige Bromfraktion ergab, nach Umwandlung in Bromwasserstoff. auf Grund einer Bromsilbersynthese das Atomgewicht Br = 79,916, das identisch ist mit dem des gewöhnlichen normalen Broms. Es scheint demnach, daß bei den Trennungsversuchen kein positives Ergebnis zu erzielen ist, jedenfalls kann der gesuchte Effekt größenordnungsmäßig nicht außerhalb der Fehlergrenze der Bestimmungsmethode liegen.
    Additional Material: 2 Tab.
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  • 16
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 212 (1933), S. 385-392 
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wurde eine Methode zur Analyse des reinen, wasserfreien Ytterbiumtrichlorids ausgearbeitet und das spezifische Gewicht des Salzes zu 3,781 bestimmt.
    Type of Medium: Electronic Resource
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  • 17
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 194 (1930), S. 293-298 
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Analyse des Thallobromids ergibt aus dem Verhältnis TIBr/Ag, in vollkommener Übereinstimmung mit der früheren Untersuchung, das Atomgewicht für Thallium TI = 204,390 ± 0,008.
    Additional Material: 1 Tab.
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  • 18
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 208 (1932), S. 53-58 
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es werden Methoden eur Gewinnung eines reinen Silberjodids durch Fällung aus wäßriger Lösung beschrieben. Das mit Hilfe dieses Silberjodids bestimmte Verhältnis AgJ : AgCl ergab das Atomgewicht J = 126,917, bezogen auf Ag = 107,880 und C1 = 34,457.
    Type of Medium: Electronic Resource
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  • 19
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Alterations in the fine structures of femaleBrugia spp. andLitomosoides carinii were investigated after in vivo treatment with curative doses of 4 compounds: CGP 20376 [2-tert-butyl-benzothiazole-5-methoxy-6-dithiocarbamic-S-(2-carboxyethyl)-ester], CGP 21833 (2-tert-butyl-benzothiazole-5-methyl-6-N-methylamino-piperazinylthiocarbonylamide), CGP 6140 [4-Nitro-4′-(N-methyl-piperazinylthiocarbonylamido)-diphenylamine] and amoscanate (4-isothiocyanato-4′-nitrodiphenylamine). All compounds caused early alterations in the somatic muscle cells. These alterations usually appeared within 24 h after treatment; they occurred later only after treatment ofL. carinii with amoscanate. InBrugia spp., swelling of the muscle cells occurred in which the glycogen deposits considerably increased in size. The electron density of the cytoplasm surrounding the myofilaments in the fibrillar protion of the muscle cells increased, and light zones appeared between the fibrils. The muscle cell mitochondria swelled, particularly their inner matrix, which became more electron-lucent, with some dense spots. InL. carinii the muscle cells were not increased in size, but their mitochondria were considerably swollen before disintegration; this was followed by disintegration of the myofilaments and vacuolization of the cytoplasm. Vacuolization before mitochondrial swelling was observed only after treatment with CGP 6140. Other tissues of this species were not altered before the 2nd day after treatment. InBrugia spp., electron-lucent areas appeared in the hypodermis either simultaneously with the alterations in the muscle cells or a few hours later. At 24 h after treatment with amoscanate, blebs were formed on the luminal side of the intestinal membrane. Although the pathological pattern is slightly different in the two species, the characteristic and very early alterations in the muscle mitochondria indicate that all compounds interfere with the energy metabolism of the filariae, which is particularly high in the very actively working muscle cells. The variations in sensitivity of hypodermal structures ofBrugia spp. to the various compounds may be due to compound differences.
    Type of Medium: Electronic Resource
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