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  • 11
    Electronic Resource
    Electronic Resource
    CHANGES IN BLOOD AND RED CELL VOLUME IN THE NEONATAL LAMB AND THE EFFECT OF INSULIN-LIKE GROWTH FACTOR I (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 23 (1996), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Blood volume was measured weekly using [51Cr]-labelled red cells in 10 lambs from 3 to 10 weeks of age. Red cell and plasma volumes were calculated using the measured blood volume and haematocrit. Other parameters, including plasma erythropoietin, urea, creatinine and glucose, were measured twice weekly. The results were compared to a group of five lambs that received an infusion of insulin-like growth factor I (IGF-I).2. In control lambs, plasma volume increased linearly by 47 ± 7 mL/week over the experimental period. Red cell volume only increased by 10 ± 2 mL/week during weeks 3–7, but then increased by 25 ± 2 mL/week over weeks 7–10. Haematocrit declined from 28.0 ± 1.6 to 24.7 ± 1.7% over weeks 3–7 and then increased to 30.7 ± 1.1% by week 10.3. In 10 control lambs infused for 8 days (starting at 22–26 days of age) with 10 mmol/L HCl, there was a decrease in plasma IGF-I concentrations, 3 days after the start of infusion. In five lambs infused for 8 days with IGF-I (6 μg/kg per h) plasma IGF-I concentration was maintained significantly (P 〈 0.01) higher than that of the controls.4. There was no significant difference in haematocrit, red cell or plasma volumes between the treatment groups and no reticulocytosis was observed. Plasma erythropoietin concentrations did not change over the infusion period in either group.5. Serum urea decreased significantly in the IGF-I infused group but serum creatinine did not change in either group during the infusion period. In both the groups, there was a significant decrease in glucose, urea and creatinine over weeks 3–10 after birth. There was no difference in growth rates between the two groups.6. Thus, it appears that the observed changes in haematocrit are due to a constant increase in plasma volume with varying rates of red cell volume increases.7. IGF-I infused at a dose that maintains physiological concentrations and alters protein metabolism does not result in increased erythropoietin or erythropoiesis during the neonatal period of the lamb.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1996.tb02584.x
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  • 12
    Electronic Resource
    Electronic Resource
    Zur feinstruktur integumentaler bildungen bei priapuliden (Halicryptus spinulosus und Priapulus caudatus) (1972)
    Springer
    Zoomorphology 72 (1972), S. 203-230 
    Details
    ISSN: 1432-234X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammentassung Die Integumente der Priapuliden Halicryptus spinulosus und Priapulus caudatus sind ähnlich aufgebaut. Die miteinander verzahnten und über lange septierte Desmosomen verbundenen Epithelzellen tragen apikal eine amorphe, in Abhgngigkeit von der Häutungsphase± geschichtete Kutikula. Ähnliche Kutikulastrukturen finden sich bei Nematoden. Der Panzer der Halicryptus-Larve ist in seiner Ultrastruktur deutlich verschieden von der Kutikula adulter Tiere and zeigt auch keine Übereinstimmung mit dem Panzer der Kinorhynchen. Die epithelialen Stacheln der Art Halicryptus spinulosus enthalten mehrere Sekretzelltypen. Die epithelialen Differenzierungen am Rumpfende von Priapulus caudatus sind durch ihre Ultrastruktur ebenfalls als sezernierende Zellkomplexe gekennzeichnet. Der Feinbau des distalen Anhangsorganes von Priapulus caudatus entspricht der Ultrastruktur von Zellen mit aktivem Ionentransport. AuBerdem ist dieses Organ Träger von Mechanorezeptoren.
    Notes: Summary The integuments of the priapulids Halicryptus spinulosus and Priapulus caudatus exhibit a similar ultrastructure. The epithelial cells, the neighbouring lateral plasma membranes of which are frequently highly interdigitated, are connected by long septate desmosomes and are apically covered by an amorphous cuticle. The latter shows a stratification, the pattern of which is dependent on the moulting phase. Similar cuticular structures are to be found in nematodes. The cuticle of the larvae of Halicryptus differs markedly from that of the adult animals and also does not show agreements with the armour of kinorhynchs. It is threelaminated and contains in the middle layer canalicular structures. The epithelial spines of Halicryptus spinulosus contain various types of secretory cells. The epithelial differentiations at the end of the body of Priapulus caudatus also represent, according to their ultrastructure, secretory cells. The fine structure of the appendicular organs of Priapulus caudatus corresponds to that of cells engaged in ion transport. In addition this organ possesses mechanoreceptors. Both priapulids carry, on the integumental papillae and within the epithelium of the body and pharynx, characteristically constructed receptors with an apical cilium surrounded by seven microvilli. They are interpreted to represent mechanoreceptors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00391552
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  • 13
    Electronic Resource
    Electronic Resource
    Zur Feinstruktur des Integumentes von Trachydemus giganteus Zelinka (Kinorhyncha) (1972)
    Springer
    Zoomorphology 71 (1972), S. 189-202 
    Details
    ISSN: 1432-234X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The integument of the Kinorhynch Trachydemus giganteus was investigated by means of electron microscope. It was found that the epidermis is composed of individual cells. The cuticle and receptor cells, which in part bear an apical cilium, exhibit arthropod characteristics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00298577
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  • 14
    Electronic Resource
    Electronic Resource
    Functional development of the meso- and metanephros (1999)
    Springer
    Pediatric nephrology 13 (1999), S. 171-178 
    Details
    ISSN: 1432-198X
    Keywords: Key words Mesonephros ; Metanephros ; Nephrogenesis ; Renin-angiotensin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  This review highlights the important roles the mesonephros may play in development. In the ovine fetus it is an excretory and endocrine organ and may contribute to the formation of normal gonads and adrenals. The metanephros of the ovine fetus has the important function of providing large quantities of dilute urine for the maintenance of amniotic and allantoic fluid volumes, essential for normal placentation and development.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670050587
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  • 15
    Electronic Resource
    Electronic Resource
    Zur Feinstruktur der Sinnesorgane von Lineus ruber O.F. Müller (Nemertini, Heteronemertini) (1971)
    Springer
    Cell & tissue research 117 (1971), S. 212-225 
    Details
    ISSN: 1432-0878
    Keywords: Sensory cells ; Cilia ; Nemertini
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Die Sinnesorgane des Vorderendes von Linens ruber werden elektronen-mikroskopisch vor allem im Hinblick auf die rezeptorischen Strukturen untersucht. Am Kopfvorderrand liegen zwei Rezeptortypen: Typ 1 ist mit 20–40, Typ 2 nur mit einer Zilie besetzt. Die Seitenwurzeln der Zilien von Typ 1 sind parallel angeordnet. Die Perikarya beider Rezeptoren liegen unterhalb des Epithelverbandes, dessen Großteil von Typ 1 eingenommen wird. In den Kopfspalten finden sich primäre Sinneszellen mit eingesenkten Zilien, deren Membran regelmäßig aufgeschwollen ist. Im Cerebralorgan dominiert ebenfalls eine primäre Sinneszelle, die reichlich efferent innerviert wird. In den Lichtrezeptoren findet sich eine Zilie unter dem distalen Mikrovillisaum. Alle beschriebenen Zilien sind deutlich voneinander und von den Wimpern der Epidermis unterschieden. Sie werden mit den Zilien der Rezeptoren anderer Tiergruppen verglichen.
    Notes: Summary The sensory organs located in the head reagion of the ribbon worm Lineus ruber have been investigated with the electron microscope. Attention has been focussed on the apical cell-structures, which are assumed to be related to sensory functions. At the anterior edge of the head two receptor-types occur: type 1 bears 20–40 apical cilia, type 2 only 1 cilium per cell. The lateral ciliary rootlets of type 1 are oriented strictly parallel. The pericarya of both receptor types of which type 1 is particularly dominant, are situated below the basement lamina of the epithelium. In the cephalic clefts primary sensory cells occur, the cilia of which are invaginated into the apical cytoplasm. Their ciliary membrane exhibits regular inflations. In the cerebral organ also primary sensory cells dominate which receive an abundant efferent nerve supply. In the light receptors only one cilium is to be found below the distal villi. The cilia of the sensory cells and also of the ordinary epidermis cells show individual characteristics not shared by the other types. Their structural peculiarities are compared with those of sensory organs of other groups of animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00330738
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  • 16
    Electronic Resource
    Electronic Resource
    Elektronenmikroskopische Untersuchung eines Mechanorezeptors von Evertebraten (Priapuliden, Oligochaeten) (1971)
    Springer
    Cell & tissue research 117 (1971), S. 226-234 
    Details
    ISSN: 1432-0878
    Keywords: Mechanoreceptors ; Epidermis ; Oligochaeta ; Priapulida
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Rezeptoren von Priapulus caudatus und Rhynchelmis limosella werden elektronenmikroskopisch untersucht. Ihre Strukturen stimmen in folgenden Merkmalen überein: Apikal steht eine Zilie, die von regelmäßig angeordneten Mikrovilli umgeben wird. Das Cytoplasma der Mikrovilli ist zentral verdichtet und im übrigen Bereich von Filamenten ausgefüllt, die im Perikaryon wurzeln. Im distalen Teil der Zelle liegt ein reich entwickeltes glattes E. R., darunter folgen Tubuli. Die Zellen werden reich innerviert. Aufgrund der strukturellen Übereinstimmung mit Mechanorezeptoren anderer Tiergruppen wird den Rezeptoren der untersuchten Formen ebenfalls eine mechanorezeptive Funktion zugeschrieben.
    Notes: Summary Epidermal receptor cells of Priapulus caudatus and Rhynchelmis limosella have been investigated with the electron microscope. The following structural peculiarities characterize these cells: an apical cilium is surrounded by regularly arranged microvilli, which contain filaments extending into the cytoplasm of the cell body. The central part of the microvilli is electron dense. The apical part of the cell contains abundant tubules of smooth E. R., below which microtubules are located. The cells are richly innervated. These elements are interpreted to represent mechanoreceptors because they have the above mentioned structures in common with mechanoreceptors of other invertebrate groups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00330739
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  • 17
    Electronic Resource
    Electronic Resource
    Über die Regeneration des Integumentes aus Zellen im Ventralnervenstrang von Phascolion strombi (Montagu) (Sipunculida) (1970)
    Springer
    Cell & tissue research 110 (1970), S. 258-267 
    Details
    ISSN: 1432-0878
    Keywords: Sipunculids ; Regeneration ; Integument
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Die Zellen des Regenerationsstranges im Bauchmark von Phascolion strombi sind in erster Linie durch elektronendichte Einschlüsse gekennzeichnet, deren Durchmesser etwa 5000 Å betragen. Bei Introvertamputation wandern diese Zellen nach vorn und bilden eine kolbenförmige Gewebemasse. Die rundlichen Einschlüsse lösen sich auf, werden zu Fasern umgebildet und aus den Zellen in das Interstitium geschleust. Diese Wanderstadien der Regenerationszellen sind durch sehr viele Glykogenrosetten und Lipideinschlüsse gekennzeichnet. Im weiteren Verlauf entstehen zwischen den distalen Zellen des Regenerates Desmosomen. Über den mit Mikrovilli versehenen Zellapices bildet sich die Kutikula, die offenbar den Sekreteinschlüssen der Regenerationszellen entstammt. Im jungen Epithel fehlen die für Regenerationsstrang und Wanderstadien typischen Einschlüsse, sein Zytoplasma ist reich an granulärem endoplasmatischen Retikulum. Die neue Muskulatur entsteht aus Amöbozyten.
    Notes: Summary The cells of the regeneration string in the ventral nerve cord of Phascolion strombi are in particular characterised by electron dense granules of 5000 Å in diameter. Following amputation of the introvert these cells migrate anteriorly and form a clublike mass of tissue. At this stage they are strikingly rich in glycogen and lipid. The globular inclusions dissolve and transform into fibers which are extruded from the cell into the interstitial space. At later phases of development desmosomes form between the distal cells of the regenerative tissue. On top of the microvilli bearing apical cell poles a cuticle develops, obviously arising from the secretion granules of the regeneration cells. The new-formed epithelium lacks inclusion bodies which are typical for the regeneration string and the migrating cells, instead its cytoplasm is rich in rough E. R. profiles. The musculature is built up by amebocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00335530
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  • 18
    Electronic Resource
    Electronic Resource
    Über den Aufbau des Integumentes der Priapuliden und der Sipunculiden [Priapulus caudatus Lamarck, Phascolion strombi (Montagu)] (1970)
    Springer
    Cell & tissue research 105 (1970), S. 55-64 
    Details
    ISSN: 1432-0878
    Keywords: Priapulida ; Sipunculida ; Integument
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Die Epidermis von Priapulus caudatus besteht aus E. R.-reichen Zellen, deren chromatinarme Kerne apikal von zahlreichen Mitochondrien umgeben werden. Distal lagert eine dicke Kutikula, die aus feinfaserigem Material besteht. Die basale Plasmamembran ist zu einem umfangreichen Labyrinth aufgefaltet. Die Epidermis von Phascolion strombi weist nur wenig endoplasmatisches Retikulum auf. In den Zellen kommen viele Tonofilamentbündel vor. Das basale Plasmalemm ist aufgefaltet. Die Kutikula besteht aus vielen Schichten rechtwinklig gegeneinander versetzter Fibrillenlagen. Dieser ultrastrukturelle Bau einer Kutikula tritt sonst nur bei den Anneliden auf. Im Bereich der Tentakel findet sich keine Kutikula. Das Epithel ist hier mit einem Mikrovillussaum versehen und trägt an manchen Stellen Zilien.
    Notes: Summary The epidermis of Priapulus caudatus consists of cells with strikingly pale nuclei and an abundant granular endoplasmic reticulum. The apical parts of the nuclei are surrounded by dense clusters of mitochondria. The thick cuticle consists of fibrous material. The basal plasmalemma exhibits up-foldings that build up a labyrinthine system of intercellular spaces. The epidermis of Phascolion strombi which is poor in endoplasmic reticulum, is characterized by many bundles of tonofilaments. The basal plasmalemma exhibits simple up-foldings. The cuticle consists of layers of fibrils, which are orientated at right angles over each other. A similar cuticle has been found in the class of Annelids. In the area of the tentacles there is no cuticle, the epithelium bears microvilli and cilia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00340564
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  • 19
    facet.materialart.
    Unknown
    Elektronenmikroskopische und physiologische Untersuchungen an Priapulidan, Sipunculiden und Echiuriden : ein Beitrag zur Biologie und Systematik (1971)
    In:  (PhD/ Doctoral thesis), Christian-Albrechts-Universität Kiel, Kiel, Germany, 53 pp
    Details
    Publication Date: 2017-09-18
    Type: Thesis , NonPeerReviewed
    Format: text
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    OceanRep: Thesis - not published by a publisher
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