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  • 11
    Electronic Resource
    Electronic Resource
    Large decrease in ocean-surface CO 2 fugacity in response to in situ iron fertilization (1996)
    [s.l.] : Nature Publishing Group
    Nature 383 (1996), S. 511-513 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The equatorial Pacific and the Southern Ocean are the world's two largest high-nitrate low-chlorophyll (HNLC) regions. Numerous incubation experiments support the possibility that iron limitation could contribute to this situation12'14 To test the iron hypothesis under natural ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/383511a0
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    Paper (German National Licenses)
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  • 12
    Electronic Resource
    Electronic Resource
    Hemodynamic effects of sodium bicarbonate (1994)
    Springer
    Intensive care medicine 20 (1994), S. 306-306 
    Details
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01708972
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  • 13
    Electronic Resource
    Electronic Resource
    Plasma ionized calcium and blood lactate concentrations are inversely associated in human lactic acidosis (1992)
    Springer
    Intensive care medicine 18 (1992), S. 286-289 
    Details
    ISSN: 1432-1238
    Keywords: Ionized calcium ; Hypocalcemia ; Lactate ; Lactic acidosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Plasma ionized calcium [Ca++] concentrations are decreased in patients having lactic acidosis. To further investigate this observation, we prospectively studied nine critically ill patients who had lactic acidosis and measured arterial pH, PCO2, [Ca++], lactate, and albumin concentrations. We found a strong association between decreased [Ca++] and increased plasma lactate concentrations (r 2=0.78,p≤0.001). This unexpected association — [Ca++] usually increases with increasing acidosis — might be clinically important and the mechanism deserves further investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01706475
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  • 14
    Electronic Resource
    Electronic Resource
    Adverse haemodynamic effects of sodium bicarbonate in metabolic acidosis (1987)
    Springer
    Intensive care medicine 13 (1987), S. 425-427 
    Details
    ISSN: 1432-1238
    Keywords: Metabolic acidosis ; Sodium bicarbonate ; Acute renal failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a patient with viral pneumonia, acute respiratory and renal failure and metabolic acidosis, a reduction in left ventricular stroke work was observed on the three occasions that 100 ml of 8.4% sodium bicarbonate was infused. Blood pressure and cardiac output decreased on two of the occassions. Since intravenous sodium bicarbonate may produce adverse cardiovascular effects, a right heart catheter should be inserted to monitor these effects when alkali therapy is administered to an acutely ill patient with metabolic acidosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00257690
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  • 15
    Electronic Resource
    Electronic Resource
    Association between plasma ionized calcium and lactate concentration (1993)
    Springer
    Intensive care medicine 19 (1993), S. 362-363 
    Details
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusion ISE are not suitable for the measurement of ionized calcium under clinical conditions when anions like acetate, lactate or malate are present in concentrations of about 5–10 mmol/l.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01694716
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  • 16
    Electronic Resource
    Electronic Resource
    Real-time estimation of dynamic particle-size distributions in a fluidized bed: Theoretical foundation (1985)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 31 (1985), S. 1202-1212 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Significant noise (random error) is common in an on-line signal when measuring the particle size distribution in a fluidized bed. The application of optimal estimation theory to obtain a filtering algorithm that can rectify such measurements is detailed. Off-line simulation studies demonstrate that the filtering algorithm yields a measure of particle size distribution that is well-behaved, accurate, and able to track in real time as conditions change in the bed.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690310718
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  • 17
    Electronic Resource
    Electronic Resource
    Comparison of linear distributed-parameter filters to lumped approximants (1986)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 32 (1986), S. 186-194 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Optimal distributed-parameter filters are commonly implemented using approximating lumped Kalman filtering theory. The effect of such an approximation is investigated. A theoretical development shows that there is a loss in the spatial noise correlation for the lumped approximants. Two numerical examples of engineering significance illustrate that one result of this loss is slower filter convergence for the lumped approximants relative to the full distributed-parameter filters.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690320203
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  • 18
    Electronic Resource
    Electronic Resource
    Optimal, real-time monitoring of particle size distribution in a fluidized bed (1986)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 32 (1986), S. 389-396 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A novel method for tracking particle size distribution dynamics in a fluidized bed yields on-line, real-time measurements of particle size distribution that are representative of actual conditions. These measurements are somewhat corrupted with noise (random error), however, and are available to the computer only at discrete time intervals. An optimal filtering algorithm combines the measurements with predictions from an idealized dynamic model to yield particle size distribution estimates that are not only on-line and real-time, but also virtually continuous and well-behaved.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690320305
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  • 19
    Electronic Resource
    Electronic Resource
    Mechanism of production of ions in electrospray mass spectrometry (1993)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 28 (1993), S. 721-728 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A mechanism for the production of multiply charged molecular ion species in electrospray mass spectrometry (ES-MS) is still required. A concise discussion of a recently published ionic solution equilibrium model offering a partial mechanism is presented. That publication proposed that the ion abundance-charge profile could be fitted by one or a series of superimposed Gaussian functions, in accord with a solution equilibrium model. It is shown that indeed a simulated mass spectrum based on a solution odel can compare well with the observed spectrum. However, some new and recently published experimental evidence is presented which shows that the ES mass spectra of many proteins give rise to multiply charged molecular ions which carry higher charges than those calculated by the model. Further, the ion abundance-charge profile is very sensitive to some experimental parameters, e.g. cone voltage; it does not necessarily reflect the solution or gaseous ion populations in the mass spectrometer source. Therefore, the concept that gaseous multi-charged ions originate from equivalently charged solvated ions in electrically neutral solution must be treated with caution.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210280612
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  • 20
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    Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score (2015)
    Oxford University Press
    Details
    Publication Date: 2015-09-02
    Description: Rationale Extracorporeal membrane oxygenation (ECMO) may provide mechanical pulmonary and circulatory support for patients with cardiogenic shock refractory to conventional medical therapy. Prediction of survival in these patients may assist in management of these patients and comparison of results from different centers. Aims To identify pre-ECMO factors which predict survival from refractory cardiogenic shock requiring ECMO and create the survival after veno-arterial-ECMO (SAVE)-score. Methods and results Patients with refractory cardiogenic shock treated with veno-arterial ECMO between January 2003 and December 2013 were extracted from the international Extracorporeal Life Support Organization registry. Multivariable logistic regression was performed using bootstrapping methodology with internal and external validation to identify factors independently associated with in-hospital survival. Of 3846 patients with cardiogenic shock treated with ECMO, 1601 (42%) patients were alive at hospital discharge. Chronic renal failure, longer duration of ventilation prior to ECMO initiation, pre-ECMO organ failures, pre-ECMO cardiac arrest, congenital heart disease, lower pulse pressure, and lower serum bicarbonate (HCO 3 ) were risk factors associated with mortality. Younger age, lower weight, acute myocarditis, heart transplant, refractory ventricular tachycardia or fibrillation, higher diastolic blood pressure, and lower peak inspiratory pressure were protective. The SAVE-score (area under the receiver operating characteristics [ROC] curve [AUROC] 0.68 [95%CI 0.64–0.71]) was created. External validation of the SAVE-score in an Australian population of 161 patients showed excellent discrimination with AUROC = 0.90 (95%CI 0.85–0.95). Conclusions The SAVE-score may be a tool to predict survival for patients receiving ECMO for refractory cardiogenic shock ( www.save-score.com ).
    Print ISSN: 0195-668X
    Electronic ISSN: 1522-9645
    Topics: Medicine
    Published by Oxford University Press
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