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  • 11
    Electronic Resource
    Electronic Resource
    Inverse pion electroproduction at threshold. π^-p-〉ne^+e^-
    Amsterdam : Elsevier
    Physics Letters B 233 (1989), S. 60-64 
    Details
    ISSN: 0370-2693
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0370-2693(89)90615-1
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    Paper (German National Licenses)
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  • 12
    Electronic Resource
    Electronic Resource
    Dalitz decay. π^0 -〉 γe^+e^- and the π^0 electromagnetic transition form factor
    Amsterdam : Elsevier
    Physics Letters B 233 (1989), S. 65-68 
    Details
    ISSN: 0370-2693
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0370-2693(89)90616-3
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    Paper (German National Licenses)
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  • 13
    Electronic Resource
    Electronic Resource
    Elastic π±-d and π±-4He scattering below 70 MeV (1982)
    Springer
    Czechoslovak journal of physics 32 (1982), S. 255-257 
    Details
    ISSN: 1572-9486
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Elastic scattering differential cross section data ofπ ± d at 65 MeV andπ ± 4He at 51 MeV are presented and compared respectively to fully relativistic 3-body and optical potential calculations including true pion absorption.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01602062
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  • 14
    Electronic Resource
    Electronic Resource
    Sodium naproxen: concentration and effect on inflammatory response mediators in human rheumatoid synovial fluid (1994)
    Springer
    European journal of clinical pharmacology 46 (1994), S. 3-7 
    Details
    ISSN: 1432-1041
    Keywords: Naproxen ; Synovial fluid ; Rheumatoid arthritis ; NSAIDs ; eicosanoid ; concentration/effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Twelve patients suffering from rheumatoid arthritis and having swollen knees were treated with 1.1 g/day of sodium naproxen administered in one dose, daily for 5 days. The 72-h wash-out period was verified by the absence of any nonsteroidal anti-inflammatory drug using a HPLC screening. Blood and synovial fluid samples were drawn just before treatment and 24 h after the last dose. Eicosanoids (PGE2, 6-keto-PGF1α, TXB2, LTB4, LTC4) in synovial fluid were determined by immunoenzy-matic assays. In plasma and synovial fluid, hyaluronic acid was assayed by radiometric assay and sodium naproxen by HPLC. Free drug was determined by equilibrium dialysis. Statistical analysis used nonparametric tests. Pain relief (evaluated on a visual scale), morning stiffness, and scores on the Lee and Ritchie indices all decreased significantly, as did PGE2 and LTB4 concentrations. The decrease in 6-keto-PGF1α and TXB2 was not significant. No significant change was found for LTC4 and hyaluronic acid. Total concentrations of sodium naproxen were equivalent in plasma (16.1 μg·ml−1) and synovial fluid (18.9 μg·ml−1). Free fractions were significantly higher in synovial fluid (0.14%) than in plasma (0.11 %), as shown by binding of the drug to human serum albumin, at various protein concentrations. Interestingly, the clinical efficacy, as shown by decreases in morning stiffness and in the Lee index score, correlated with the free concentration of naproxen in synovial fluid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00195907
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  • 15
    Electronic Resource
    Electronic Resource
    Relationship between inbreeding depression and inbreeding coefficient in maritime pine (Pinus pinaster) (1996)
    Springer
    Theoretical and applied genetics 92 (1996), S. 347-356 
    Details
    ISSN: 1432-2242
    Keywords: Key words Pinus pinaster  ;  Inbreeding depression  ; Filled seeds  ;  Adult growth  ;  Genetic load
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  The relationship between inbreeding depression and inbreeding coefficient (F) for several important traits was investigated in an 11-year trial of maritime pine (Pinus pinaster). Five levels of inbreeding (F=0; 0.125; 0.25; 0.5; 0.75) were obtained in a mating design involving ten plus-trees, or their progenies, as parents (total of 51 families). For F=0.75, the mean inbreeding depressions were 27% for height, 37% for circumference at breast height (63% for bole volume), 23% for basal straightness (better straightness of the inbred trees), and 89% for female fertility (number of cones). Large differences were observed among inbred families for the same level of inbreeding. The evolution of depression with F was more or less linear, depending on the traits. Significant differences among F-levels appeared very early for height (from 5-years of age). Inbreeding depression was much more expressed during unfavorable years than during favorable years for yearly height growth. When compared with other Pinus species, maritime pine appears to be less affected by inbreeding, especially for the percentage of filled seeds and general vigor. A reduced genetic load in maritime pine may result from the evolutionary history of the species and its scattered distribution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001220050134
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  • 16
    Electronic Resource
    Electronic Resource
    Relationship between inbreeding depression and inbreeding coefficient in maritime pine (Pinus pinaster) (1996)
    Springer
    Theoretical and applied genetics 92 (1996), S. 347-356 
    Details
    ISSN: 1432-2242
    Keywords: Pinus pinaster ; Inbreeding depression ; Filled seeds ; Adult growth ; Genetic load
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The relationship between inbreeding depression and inbreeding coefficient (F) for several important traits was investigated in an 11-year trial of maritime pine (Pinus pinaster). Five levels of inbreeding (F=0; 0.125; 0.25; 0.5; 0.75) were obtained in a mating design involving ten plus-trees, or their progenies, as parents (total of 51 families). For F=0.75, the mean inbreeding depressions were 27% for height, 37% for circumference at breast height (63% for bole volume), 23% for basal straightness (better straightness of the inbred trees), and 89% for female fertility (number of cones). Large differences were observed among inbred families for the same level of inbreeding. The evolution of depression with F was more or less linear, depending on the traits. Significant differences among F-levels appeared very early for height (from 5-years of age). Inbreeding depression was much more expressed during unfavorable years than during favorable years for yearly height growth. When compared with other Pinus species, maritime pine appears to be less affected by inbreeding, especially for the percentage of filled seeds and general vigor. A reduced genetic load in maritime pine may result from the evolutionary history of the species and its scattered distribution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00223678
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  • 17
    Electronic Resource
    Electronic Resource
    Evaluation of chilling sensitivity in different rice varieties. Relationship between screening procedures applied during germination and vegetative growth (1996)
    Springer
    Euphytica 89 (1996), S. 201-210 
    Details
    ISSN: 1573-5060
    Keywords: Oryza sativa ; rice ; chilling ; electrolyte leakage ; chlorophyll fluorescence ; seed dormancy ; seed germination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Rice varieties were screened for chilling tolerance during germination and vegetative growth using different techniques. The effects of temperature during germination were investigated from 10 to 25°C. The screening was most effective at 10°C. Time of data collection has to be considered in order to discriminate slow germinating from chilling sensitive varieties. Chilling survival tests (10°C) applied at the 2-leaf stage revealed that different chilling durations brought complementary results: the longer treatments allowed to identify the most tolerant varieties, while shorter treatments allowed to distinguish intermediate from most sensitive rices. Results of chilling tests applied at the 2- and the 8-leaf stages showed a high correlation. Low-temperature electrolyte leakage and low-temperature fluorescence were also highly correlated to each other and to survival tests applied at the same development stage. By contrast, weak correlations were observed between low-temperature germination and plantlet chilling survival. It is concluded that low-temperature electrolyte leakage and low-temperature fluorescence are good indicators of chilling tolerance during the vegetative growth. The possibility to use a chilling screening procedure applied at this stage in order to predict the chilling tolerance at other development stages is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00034606
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  • 18
    Electronic Resource
    Electronic Resource
    Adolescent osteoporosis disclosing familial osteopenia (1992)
    Springer
    Clinical rheumatology 11 (1992), S. 558-561 
    Details
    ISSN: 1434-9949
    Keywords: Familial Juvenile Osteoporosis ; Genetic ; Densitometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The observations of familial juvenile osteoporosis, presumably of genetic origin are exceptional. The authors report the observation of a 16-year old adolescent suffering from osteoporosis, confirmed by histomorphometry and decrease in bone density (lumbar vertebrae 0.79 g/cm2 and femoral neck 0.88 g/cm2: LUNAR DPX). We prescribed fluorine and calcium therapy. Lumbar bone density increases by 11% and bone density of the thighbone neck by 7.6%. We cannot rule out growth as a factor in the changes observed, given that the propositus is only 16. A densitometric investigation performed in 4 of his 12 brothers shows a decrease in the lumbar bone mineral content (from 61 to 94% expressed as Z score). A genotypic origin seems to be conceivable, especially since no other cause could be considered (endocrinal, alimentary...). On the other hand, there is no argument in favour of osteogenesis imperfecta disease. The bone densitometry is a useful diagnostic means to detect familial forms of osteoprosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02283119
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  • 19
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    Intracellular nicotinamide adenine dinucleotide promotes TNF-induced necroptosis in a sirtuin-dependent manner (2015)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2015-12-08
    Description: Intracellular nicotinamide adenine dinucleotide promotes TNF-induced necroptosis in a sirtuin-dependent manner Cell Death and Differentiation 23, 29 (January 2016). doi:10.1038/cdd.2015.60 Authors: N Preyat, M Rossi, J Kers, L Chen, J Bertin, P J Gough, A Le Moine, A Rongvaux, F Van Gool & O Leo
    Print ISSN: 1350-9047
    Electronic ISSN: 1476-5403
    Topics: Biology , Medicine
    Published by Nature Publishing Group (NPG)
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  • 20
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    The microbial genomics of arsenic (2016)
    Oxford University Press
    Details
    Publication Date: 2016-03-03
    Description: Arsenic, which is a major contaminant of many aquatic ecosystems worldwide, is responsible for serious public health issues. However, life has evolved various strategies for coping with this toxic element. In particular, prokaryotic organisms have developed processes enabling them to resist and metabolize this chemical. Studies based on genome sequencing and transcriptome, proteome and metabolome profiling have greatly improved our knowledge of prokaryotes’ metabolic potential and functioning in contaminated environments. The increasing number of genomes available and the development of descriptive and comparative approaches have made it possible not only to identify several genetic determinants of the arsenic metabolism, but also to elucidate their phylogenetic distribution and their modes of regulation. In addition, studies using functional genomic tools have established the pleiotropic character of prokaryotes’ responses to arsenic, which can be either common to several species or species-specific. These approaches also provide promising means of deciphering the functioning of microbial communities including uncultured organisms, the genetic transfers involved and the possible occurrence of metabolic interactions as well as the evolution of arsenic resistance and metabolism.
    Print ISSN: 0168-6445
    Electronic ISSN: 1574-6976
    Topics: Biology
    Published by Oxford University Press
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