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  • 11
    Digitale Medien
    Digitale Medien
    Oxford UK : Blackwell Science Ltd
    Cytopathology 12 (2001), S. 0 
    ISSN: 1365-2303
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 12
    ISSN: 1365-2303
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: This is a statistical analysis of individual NHS Cervical Screening Programme laboratories screening smear ‘pick-up’ rates (defined here as percentage low grade and percentage high grade of total adequate smears for ages 20–64 years derived from general practitioners and community clinics) in relation to their nonscreening smear workload proportion (here defined as percentage nonscreening smears of total laboratory workload from all sources for all ages). This was achieved by the use of three one way anova models in order to receive a complete overview of the results. The models were applied to the following: (1) Laboratories with a total workload of less than 15 000 general practitioner (GP) and community clinic smears; (2) laboratories with a total workload of greater than 15000 GP and community smears and; (3) all laboratories (i.e. a combination of 1 and 2). The ‘test’ groups within each of these models comprised three subgroups based on the percentage of laboratory workload that consisted of smears from a nonscreening source. This figure ranged from 2.8% to 82.6%. The subgroups were divided so as to contain approximately the same number of laboratories in each one (172 laboratories in total, 42 with workload 〈 15000 and 130 with 〉 15000). The results show that laboratories high and low grade pick-up rates have a positively correlated but variable relationship with the proportion of their workload that consists of nonscreening smears. The results show significance overall at the 5% level for high grade and the 10% level for low grade (high grade at P= 0.045 and low grade at P= 0.071). Significance for laboratories viewing less than 15000 screening smears at the 1% level (high grade P= 0.006 and low grade P= 0.005). They show no significance, however, for laboratories viewing more than 15000 screening smears (high grade P= 0.457 and low grade P= 0.622). There is an intriguing possibility that a greater exposure to abnormal smears results in a greater tendency to detect them. The current data provides no evidence to support the NHS Executive's use of 15000 as a designated figure when quality monitoring and service provision becomes a specific issue. The closure or amalgamation of laboratories with workloads less than this would appear to have no scientific evidence base.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 13
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Science Ltd
    Cytopathology 10 (1999), S. 0 
    ISSN: 1365-2303
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Accepted for publication 19 February 1999THE PASTThe value of EQA in pathology, including proficiency testing in gynaecological cytology, has been the subject of much recent lively debate1–6. In summary, the proven role of EQA in the monitoring of personal performance and ability is still uncertain. Furthermore, its potential to prevent critical incidents remains purely speculative. Also, whether EQA would be better replaced, for some or all professional groups, by other methods of quality assurance is unknown. Similarly, whether EQA can justify the considerable professional time, effort and expense involved has not been resolved.〈section xml:id="abs1-1"〉〈title type="main"〉THE PRESENTNot surprisingly, events at Kent & Canterbury Hospitals abruptly halted much of the debate about the foregoing issues7. Indeed, as a direct consequence of this and other incidents, the NHS Executive stipulated unilaterally that EQA is now mandatory within the NHS Cervical Screening Programme (CSP)8 and reinforced the necessity for all qualified laboratory staff to participate8–10. A surprise, however, was the Executive's enlightened comments on EQA. First, and of greatest significance, that the principal function of EQA in pathology is to improve standards and advance quality through personal education. Second, that EQA should be seen to complement other QA systems for the early identification of potential problems which might affect patient care. Third, that the identification of individual poor performance through EQA will be exceptional and in essence is a by-product of the basic educational exercise. The latter conclusion was drawn, as far as one can judge, from previous experience with the NHS Breast Screening Programme (NHSBSP) EQA.〈section xml:id="abs1-2"〉〈title type="main"〉THE FUTURE—PERSONAL SUGGESTIONS FOR OPEN DEBATE
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 14
    Digitale Medien
    Digitale Medien
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 106 (1997), S. 6552-6563 
    ISSN: 1089-7690
    Quelle: AIP Digital Archive
    Thema: Physik , Chemie und Pharmazie
    Notizen: We present dynamical studies of the surface photochemistry of dimethylcadmium (DMCd) adsorbed on GaAs(110) and CdTe(110) surfaces. This important precursor for chemical vapor deposition is studied using time-of-flight (TOF) spectroscopy in conjunction with temperature programmed desorption (TPD). For the case of greater than one monolayer coverages, on these surfaces, both photofragmentation and photodesorption are observed following irradiation. The relative probabilities of these two processes are found to be strongly dependent on adsorbate coverage and incident photon energy. Direct photoabsorption by the adsorbed molecule is found to dominate the photofragmentation process, with the substrate strongly reducing the probability of photofragmentation at low coverages due to the operation of substrate mediated channels for excited state relaxation. The CH3 fragments observed following photodissociation are found to have kinetic energies that are invariant with the energy of the exciting photon (193 and 248 nm), an effect attributed to an efficient curve crossing between excited states in this molecule. The molecular desorption process is found to exhibit an unusual coverage dependence which is linked to the probability of deposition of a significant amount of vibrational excitation in the overlayer via substrate mediated de-excitation processes. Following the adsorption of one monolayer on the GaAs substrate, the photochemistry observed is significantly different due to the thermal dissociation of DMCd to form adsorbed methylgallium moieties. In this case, multiple features are observed in the TOF spectrum with kinetic energies significantly different to those observed for the gas phase or physisorbed molecule. Correlation of the TOF spectral features with thermal desorption data allows these TOF features to be assigned to specific adsorbed intermediates. © 1997 American Institute of Physics.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 15
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 18 (1991), S. 0 
    ISSN: 1365-2559
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 16
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 17 (1990), S. 0 
    ISSN: 1365-2559
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 17
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 21 (1992), S. 0 
    ISSN: 1365-2559
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 18
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Science Ltd
    Histopathology 47 (2005), S. 0 
    ISSN: 1365-2559
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 19
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 13 (1988), S. 0 
    ISSN: 1365-2559
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: There have been few reports of gastric carcinosarcoma. We report the first case of gastric adenocarcinoleiomyosarcoma in which glandular and smooth muscle differentiation has been definitively demonstrated using transmission electron microscopy and immunohistology.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 20
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 13 (1988), S. 0 
    ISSN: 1365-2559
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Myxoid stromal change is seen in a number of benign and malignant tumours in the skin and soft tissues but has not previously been reported in malignant melanoma. Myxoid change can occur in malignant melanoma and cause diagnostic confusion with colloid (mucinous) adenocarcinoma.
    Materialart: Digitale Medien
    Standort Signatur Einschränkungen Verfügbarkeit
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