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  • 1
    Online Resource
    Online Resource
    MDPI AG ; 2020
    In:  Children Vol. 7, No. 4 ( 2020-04-01), p. 26-
    In: Children, MDPI AG, Vol. 7, No. 4 ( 2020-04-01), p. 26-
    Abstract: Saipan is a United States (US) territory Western Pacific island where little recent data exists regarding epidemiology, clinical presentation, and standard of care for pediatric seizures. This paper characterizes these features in Saipan’s pediatric population with comparisons to mainland US. This is a retrospective chart review of all pediatric patients with a history of seizures at the island’s only hospital and major private neurology clinic over a 10-year period. Variables regarding demographics, presentation, diagnosis, and treatment were collected. A total of 144 patients were included, with 101 patients diagnosed with febrile seizures and 31 patients diagnosed with non-febrile seizures. Age at first presentation peaked at 1 year old overall. The most common identified etiology of epilepsy was found to be hypoxic injury (39%), hemorrhagic injury (10%), cerebral malformation (6%), and brain mass (6%). Simple versus complex classification of febrile seizures, etiologies, and first-line treatment for non-febrile seizures were comparable to the mainland US. Electroencephalogram (EEG) was not used consistently in diagnosis. The findings from this study demonstrate that clinical presentations of pediatric seizures in Saipan are comparable to those in the mainland US.
    Type of Medium: Online Resource
    ISSN: 2227-9067
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2732685-8
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  • 2
    Online Resource
    Online Resource
    Wiley ; 2020
    In:  The Laryngoscope Vol. 130, No. 3 ( 2020-03), p. 812-817
    In: The Laryngoscope, Wiley, Vol. 130, No. 3 ( 2020-03), p. 812-817
    Abstract: To study a cohort of children referred for full‐night polysomnography (PSG) due to suspicion of obstructive sleep apnea (OSA). We examined the relationship between asthma, obesity, and severe OSA (sOSA). Methods We performed a retrospective case control analysis of children, ages 9 to 17 years, who underwent full‐night PSG. The primary goal was to determine the association between asthma, obesity, and sOSA (apnea‐hypopnea index ≥10). We used multiple logistic regression analysis to estimate these associations after controlling for covariates. A P value of ≤.05 was considered significant. Results The study included 367 children (mean [standard deviation] age 14 years (1.7), 56% male, 43% Hispanic). The prevalence of asthma was 188 of 367 (52%); obesity was 197 of 367 (54%); and sOSA was 109 of 367 (30%). sOSA was less likely in asthmatics (coefficient = −0.59; standard error [SE] = 0.23; P = .01; odds ratio [OR] = 0.55; 95% confidence interval [CI] = 0.34 to 0.88) and more likely with obesity (coefficient = 0.89; SE = 0.24; P 〈 .001; OR = 2.4; 95% CI = 1.5 to 3.9). The presence of asthma reduced the likelihood of sOSA by an average of 14% among obese patients and 9% among nonobese patients. These associations held even after controlling for age, sex, race, income, and tonsillar hypertrophy. Conclusion The presence of asthma reduced, whereas obesity increased the likelihood of sOSA among a large cohort of older children referred for PSG. These relationships were additive. Further research is indicated regarding these relationships. Level of Evidence 3b Laryngoscope , 130:812–817, 2020
    Type of Medium: Online Resource
    ISSN: 0023-852X , 1531-4995
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2026089-1
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  • 3
    Online Resource
    Online Resource
    Elsevier BV ; 2019
    In:  Journal of the American Academy of Child & Adolescent Psychiatry Vol. 58, No. 10 ( 2019-10), p. S214-S215
    In: Journal of the American Academy of Child & Adolescent Psychiatry, Elsevier BV, Vol. 58, No. 10 ( 2019-10), p. S214-S215
    Type of Medium: Online Resource
    ISSN: 0890-8567
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2019
    detail.hit.zdb_id: 2022051-0
    SSG: 5,2
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  • 4
    In: The Laryngoscope, Wiley, Vol. 130, No. 5 ( 2020-05), p. 1339-1342
    Abstract: To evaluate a cohort of obese adolescents with obstructive sleep apnea (OSA) to determine if increased yearly weight gain was a predictor of severe OSA. Study Design Retrospective cohort study. Methods Obese adolescents (body mass index percentile 〉 95% for that age and sex based upon the Centers for Disease Control and Prevention weight classifications), ages 12 to 17 years, referred for full night polysomnography (PSG) were analyzed. We examined demographics, weight classifications, yearly weight gain from age 9 years onward, PSG data (apnea‐hypopnea index), and tonsil size. We performed a mixed‐effect linear regression model to test whether the velocity of weight gain was increased in obese patients with severe OSA when compared to those without severe OSA. Results This study included 166 obese adolescents, 105 with and 61 without severe OSA. The average age was 14 years and was predominately male (57%) and Hispanic (44%). The regression analysis found that the yearly change in weight among obese adolescents with severe OSA was significantly higher than those without (B = 1.4, standard error = 0.50, P = .005, 95% confidence interval: 0.42–2.4). For the group with severe OSA, weight increased 6.5 kg every year before their PSG, whereas for those without, weight increased 5.1 kg per year. Conclusions The rate of weight gain over time is an important predictor of severe OSA in obese adolescents. Level of Evidence 3b Laryngoscope , 130:1339–1342, 2020
    Type of Medium: Online Resource
    ISSN: 0023-852X , 1531-4995
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2026089-1
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