In:
International Journal of Biomedical Science, International Assotiation of Biomedical Sciences, ( 2008-09-15), p. 245-247
Abstract:
We report two recent, successful cases in treating active chronic hepatitis C patients (genotype 2a) with a lower-dose and long-term intermittent interferon therapy. Case 1: A 67-year-old female received IFN-alpha 3 MU twice a week. Biochemical and virological remissions were achieved after 4 weeks and 14 months, respectively. We changed the IFN to pegylated-interferon alpha-2a (P-IFN) 45 μg once a week. After which, we successfully reduced the frequency of injections to once a month while maintaining both remissions. Case 2: A 61-year-old male had received a conventional genetical recombination interferon therapy. However, the hepatitis recurred. He was given IFN-alpha 3 MU once a week. A biochemical remission was achieved after 3 months. After 7 months, we changed the IFN to P-IFN 90 μg once a week, and a virological remission soon occurred. Then, we also could reduce the frequency to once every two months. Our novel strategy using P-IFN is safe and economic.
Type of Medium:
Online Resource
ISSN:
1550-9702
,
1555-2810
DOI:
10.59566/IJBS.2008.4245
Language:
Unknown
Publisher:
International Assotiation of Biomedical Sciences
Publication Date:
2008
detail.hit.zdb_id:
2228461-8
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