In:
Biology of the Cell, Wiley, Vol. 90, No. 9 ( 1998-12), p. 605-613
Abstract:
We have earlier reported partial cloning of a cDNA of a chick atrial myosin heavy chain (MHC) gene, CCSV2 and its expression pattern in embryonic chick hearts (Oana et al (1995) Eur J Cell Biol 67, 42–49). In this study, five overlapping cDNA clones (including CCSV2) which together encode the entire open reading frame of the chick atrial MHC gene were characterized, and both the entire nucleotide sequence consisting of 5825 bases and the deduced amino acid sequence consisting of 1931 amino acids determined. Reinvestigation of the nucleotide sequence of the previously reported and presumably different chick atrial specific MHC cDNA clone, AMHC1 (Yutzey et al (1994) Development 120, 871–883), revealed that our clone and AMHC1 encoded the same MHC. The chick atrial MHC gene was strongly expressed in developing chick atria from a very early stage (Hamburger and Hamilton stage 9, 29–33 h) to the adult stage. This gene was also expressed, although weakly, in the ventricle, somite (the precursor to skeletal muscle) and skeletal muscle during embryonic stages but not in adults.
Type of Medium:
Online Resource
ISSN:
0248-4900
,
1768-322X
DOI:
10.1111/boc.1998.90.issue-9
DOI:
10.1111/j.1768-322X.1998.tb01069.x
Language:
English
Publisher:
Wiley
Publication Date:
1998
detail.hit.zdb_id:
245745-3
detail.hit.zdb_id:
2011750-4
SSG:
12
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