In:
Helvetica Chimica Acta, Wiley, Vol. 99, No. 4 ( 2016-04), p. 302-305
Abstract:
Two new flavonoids, 1 and 2 , together with two known flavonoids, tephrosin ( 3 ) and 12a‐hydroxy‐ α ‐toxicarol ( 4 ), were isolated from the whole herb of Derris eriocarpa How . The structures and absolute configurations of the new compounds were elucidated on the basis of their MS , NMR , and ECD data. The structures of the known compounds were established by extensive spectroscopic ( MS , 1D‐ and 2D‐ NMR ) analyses and comparison with the literature data. All compounds were isolated from D . eriocarpa for the first time. Compound 3 showed modest inhibitory activities against the growth of human cancer cells HEL and A549 with the IC 50 values of 15.03 ± 0.62 and 13.27 ± 0.39 μ m , respectively.
Type of Medium:
Online Resource
ISSN:
0018-019X
,
1522-2675
DOI:
10.1002/hlca.201500247
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
74-7
detail.hit.zdb_id:
1475013-2
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