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  • 1
    Online Resource
    Online Resource
    Biomedical and Antioxidant Potentialities in Chilli: Perspectives and Way Forward
    MDPI AG ; 2022
    In:  Molecules Vol. 27, No. 19 ( 2022-09-27), p. 6380-
    Details
    In: Molecules, MDPI AG, Vol. 27, No. 19 ( 2022-09-27), p. 6380-
    Abstract: Worldwide, since ages and nowadays, traditional medicine is well known, owing to its biodiversity, which immensely contributed to the advancement and development of complementary and alternative medicines. There is a wide range of spices, herbs, and trees known for their medicinal uses. Chilli peppers, a vegetable cum spice crop, are bestowed with natural bioactive compounds, flavonoids, capsaicinoids, phytochemicals, phytonutrients, and pharmacologically active compounds with potential health benefits. Such compounds manifest their functionality over solo-treatment by operating in synergy and consortium. Co-action of these compounds and nutrients make them potentially effective against coagulation, obesity, diabetes, inflammation, dreadful diseases, such as cancer, and microbial diseases, alongside having good anti-oxidants with scavenging ability to free radicals and oxygen. In recent times, capsaicinoids especially capsaicin can ameliorate important viral diseases, such as SARS-CoV-2. In addition, capsaicin provides an ability to chilli peppers to ramify as topical agents in pain-relief and also benefitting man as a potential effective anesthetic agent. Such phytochemicals involved not only make them useful and a much economical substitute to wonder/artificial drugs but can be exploited as obscene drugs for the production of novel stuffs. The responsibility of the TRPV1 receptor in association with capsaicin in mitigating chronic diseases has also been justified in this study. Nonetheless, medicinal studies pertaining to consumption of chilli peppers are limited and demand confirmation of the findings from animal studies. In this artifact, an effort has been made to address in an accessible format the nutritional and biomedical perspectives of chilli pepper, which could precisely upgrade and enrich our pharmaceutical industries towards human well-being.
    Type of Medium: Online Resource
    ISSN: 1420-3049
    URL: Article
    DOI: 10.3390/molecules27196380
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2008644-1
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  • 2
    Online Resource
    Online Resource
    Physico-Chemical Properties of Red Pepper (Capsicum annuum L.) as Influenced by Different Drying Methods and Temperatures
    MDPI AG ; 2022
    In:  Processes Vol. 10, No. 3 ( 2022-02-28), p. 484-
    Details
    In: Processes, MDPI AG, Vol. 10, No. 3 ( 2022-02-28), p. 484-
    Abstract: An experiment was carried out in the laboratories of the Department of Food Engineering, Department of Vegetable Science, and Department of Plantation Spices Medicinal and Aromatic crops, Bidhan Chandra Krishi Viswavidyalaya (BCKV), West Bengal, India. The work was performed during 2018ā€“2019 and 2019ā€“2020 with different drying methods including sun drying, solar drying and oven drying. In oven drying, different temperatures such as 50, 55, 60, 65, and 70 Ā°C were considered. A randomized complete block design (RCBD) was designed with seven treatments and three replications. Experimental results were significantly varied among the treatments as influenced by different drying methods and temperatures. Minimum time taken (480 min) to reach safe moisture content was recorded in T7 (oven drying at 70 Ā°C), whereas maximum values in color components such as L* value (24.55), a* value (32.14), b* value (20.53), and pungency score (7.85) were recorded in T6 (oven drying at 65 Ā°C). However, the highest texture (1180.81) was observed in T1 (sun drying). Biochemical parameters were significantly varied among the treatments. The maximum amounts of ascorbic acid (56.06 mg/100 g) and oleoresin content (10.72) were found in T3 (oven drying at 50 Ā°C), whereas minimum values of biochemical parameters were recorded by T1 (sun drying) and T2 (solar drying) methods, respectively. Mathematical relationships were found in different drying methods and temperatures. Models such as the Lewis, Page, Modified Page, and Henderson and Pabis models were selected to fit the data. Maximum R2 value (0.9835) was found in both the Page and Modified Page models with similar values of drying method and temperature at 65 Ā°C. This value was the highest among all models in all drying temperatures. However, the lowest Ļ‡2, and RMSE values (0.000818 and 0.027261, respectively) were recorded with the Page model.
    Type of Medium: Online Resource
    ISSN: 2227-9717
    URL: Article
    DOI: 10.3390/pr10030484
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2720994-5
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  • 3
    Online Resource
    Online Resource
    Genetic Relatedness Between Quantitative and Qualitative Parameters in Onion ( Allium cepa L.)
    Springer Science and Business Media LLC ; 2013
    In:  Vegetos- An International Journal of Plant Research Vol. 26, No. 1 ( 2013), p. 151-
    Details
    In: Vegetos- An International Journal of Plant Research, Springer Science and Business Media LLC, Vol. 26, No. 1 ( 2013), p. 151-
    Type of Medium: Online Resource
    ISSN: 0970-4078 , 2229-4473
    URL: Article
    DOI: 10.5958/j.2229-4473.26.1.021
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2013
    detail.hit.zdb_id: 2632294-8
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  • 4
    Online Resource
    Online Resource
    Metallic and metal oxide-derived nanohybrid as a tool for biomedical applications
    Elsevier BV ; 2022
    In:  Biomedicine & Pharmacotherapy Vol. 155 ( 2022-11), p. 113791-
    Details
    In: Biomedicine & Pharmacotherapy, Elsevier BV, Vol. 155 ( 2022-11), p. 113791-
    Type of Medium: Online Resource
    ISSN: 0753-3322
    URL: Article
    DOI: 10.1016/j.biopha.2022.113791
    RVK:
    XA 10000
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 1501510-5
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  • 5
    Online Resource
    Online Resource
    Agri-biotechnology of coriander (Coriandrum sativum L.): an inclusive appraisal
    Springer Science and Business Media LLC ; 2022
    In:  Applied Microbiology and Biotechnology Vol. 106, No. 3 ( 2022-02), p. 951-969
    Details
    In: Applied Microbiology and Biotechnology, Springer Science and Business Media LLC, Vol. 106, No. 3 ( 2022-02), p. 951-969
    Type of Medium: Online Resource
    ISSN: 0175-7598 , 1432-0614
    URL: Article
    DOI: 10.1007/s00253-022-11787-4
    RVK:
    WA 15000
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 1464336-4
    SSG: 12
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  • 6
    Online Resource
    Online Resource
    Gynandropsis pentaphylla DC Extracts on the Production of Microbial Proteins
    Science Alert ; 2011
    In:  International Journal of Pharmacology Vol. 7, No. 6 ( 2011-8-1), p. 674-674
    Details
    In: International Journal of Pharmacology, Science Alert, Vol. 7, No. 6 ( 2011-8-1), p. 674-674
    Type of Medium: Online Resource
    ISSN: 1811-7775
    URL: Article
    DOI: 10.3923/ijp.2011.674.674
    Language: Unknown
    Publisher: Science Alert
    Publication Date: 2011
    detail.hit.zdb_id: 2177288-5
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  • 7
    Online Resource
    Online Resource
    Deciphering the Immunomodulatory Role of Cyclin-Dependent Kinase 4/6 Inhibitors in the Tumor Microenvironment
    MDPI AG ; 2023
    In:  International Journal of Molecular Sciences Vol. 24, No. 3 ( 2023-01-23), p. 2236-
    Details
    In: International Journal of Molecular Sciences, MDPI AG, Vol. 24, No. 3 ( 2023-01-23), p. 2236-
    Abstract: Cancer is characterized by persistent cell proliferation driven by aberrant cell cycle regulation and stimulation of cyclin-dependent kinases (CDKs). A very intriguing and potential approach for the development of antitumor medicines is the suppression of CDKs that lead to induction of apoptosis and cell cycle arrest. The shift of the cell cycle from the G0/G1 phase to the S phase, which is characterized by active transcription and synthesis, depends on the development of the cyclin D-CDK4/6 complex. A precise balance between anticancer activity and general toxicity is demonstrated by CDK inhibitors, which can specifically block CDK4/6 and control the cell cycle by reducing the G1 to S phase transition. CDK4/6 inhibitors have recently been reported to exhibit significant cell growth inhibition via modulating the tumour microenvironment in cancerous cells. One significant new understanding is that these inhibitors serve important functions in the interaction among tumour cells and the host immune system in addition to being cytostatic. Herein, we discuss the biological significance of CDK4/6 inhibitors in cancer therapeutics, as well as their biological impact on T cells and other important immune cells. Furthermore, we explore the integration of preclinical findings of these pharmaceuticalsā€™ ability to enhance antitumor immunity.
    Type of Medium: Online Resource
    ISSN: 1422-0067
    URL: Article
    DOI: 10.3390/ijms24032236
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2019364-6
    SSG: 12
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  • 8
    Online Resource
    Online Resource
    Elicitor-Mediated Response of Growth, Yield, and Quality of Kalmegh (Andrographis paniculata Wall. ex Nees, Family Acanthaceae)
    MDPI AG ; 2023
    In:  Agronomy Vol. 13, No. 9 ( 2023-09-02), p. 2313-
    Details
    In: Agronomy, MDPI AG, Vol. 13, No. 9 ( 2023-09-02), p. 2313-
    Abstract: With the objective of studying the influence of elicitors on the growth, yield, and quality of kalmegh, we carried out an investigation for two consecutive years. Nine treatments with three replications were laid out in a completely randomized design (CRD). Chitosan (CHT), yeast extract (YE), jasmone acid (JA), and salicylic acid (SA)were evaluated at different concentrations. The CHT treatment at 1000 ppm exhibited the tallest plant height (73.91 cm) and the highest number of secondary branches (29.07) at the time of harvest. The primary branches and number of leaves per plant were highest with the CHT treatment at 1000 ppm (26.36; 88.32), and were not significantly different with the SA treatment at 200 ppm (26.28; 81.51). The plant spread was the highest with the SAtreatment at 200 ppm (35.46 cm2) and was not significantly different with the CHT treatment at 1000 ppm (35.11 cm2). The CHT and SA sprays did not result in significant changes in yield parameters, but the highest fresh (42.34 g) and dry (18.30) herbage yields per plant were exhibited with the SA treatment at 200 ppm. The highest total chlorophyll (4.459 mg gāˆ’1) and total andrographolide (3.494%) contents were recorded after treatment with the SA spray at 200 ppm. A significant and positive improvement in the growth, yield, and quality of kalmegh was noticed with the salicylic acid spray treatment at 200 ppm 30 and 60 days after sowing (DAS), signifying its benefits for the cultivation of kalmegh in terms of high productivity, quality, and better returns for farmers.
    Type of Medium: Online Resource
    ISSN: 2073-4395
    URL: Article
    DOI: 10.3390/agronomy13092313
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2607043-1
    SSG: 23
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  • 9
    Online Resource
    Online Resource
    Dynamics of Drying Turmeric Rhizomes (Curcuma longa L.) with Respect to Its Moisture, Color, Texture and Quality
    MDPI AG ; 2022
    In:  Agronomy Vol. 12, No. 6 ( 2022-06-13), p. 1420-
    Details
    In: Agronomy, MDPI AG, Vol. 12, No. 6 ( 2022-06-13), p. 1420-
    Abstract: Drying involves removing moisture from food. Therefore, to preserve the phenolic and bioactive compounds such as curcumin, dimethoxy curcumin and bisdemethoxi curcumin, etc., an efficient drying method is considered necessary. The primary drying methods are sun drying, hot air oven drying and fluidized bed drying. Traditional drying methods result in the loss of volatile oil (up to 25%) by evaporation and destruction of some light-sensitive oil constituents. Three methods of drying Turmeric with pretreatments boiled/unboiled and whole/sliced (2.5 cm long) were compared on physical and quality parameters. Texture analysis from sundry sliced boiled rhizomes achieved maximum peak force (45.40 kg), which was an indication of maximum uniform drying. Moisture content was strongly and significantly associated with drying time in different drying methods. Out of the three drying methods, in general, the sun drying showed a declining trend of L*, a* and b* values with drying time. Whereas a slower rate of decrease in L*, a* and b* values was predominant in the oven dry method. Interestingly, in the case of the fluidized method, almost static L*, a* and b* values were measured at 3 h of drying onwards after a declining trend of those values. In the case of sun and oven drying, the hue angle reached its peak at the fourth hour of drying, then gradually declined up to final drying. However, for fluidized bed drying, it had a continuous declining trend for other parameters such as chroma and total color change; there was a sharp decreasing trend for all throughout. Turmeric whole boiled dried in the sun produced the maximum curcumin (5.82%) and the sliced boiled ones produced the maximum oleoresin (8.10%), indicating good quality powdered product among all other drying treatments. Considering all the aspects, it is recommended that sun drying should be followed in post-harvest operations, as it produces a quality powder with comparatively more curcumin, despite its longer drying time.
    Type of Medium: Online Resource
    ISSN: 2073-4395
    URL: Article
    DOI: 10.3390/agronomy12061420
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2607043-1
    SSG: 23
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  • 10
    Online Resource
    Online Resource
    Healing indigestion: a phytotherapeutic review
    Springer Science and Business Media LLC ; 2022
    In:  Advances in Traditional Medicine Vol. 22, No. 3 ( 2022-09), p. 437-453
    Details
    In: Advances in Traditional Medicine, Springer Science and Business Media LLC, Vol. 22, No. 3 ( 2022-09), p. 437-453
    Type of Medium: Online Resource
    ISSN: 2662-4052 , 2662-4060
    URL: Article
    DOI: 10.1007/s13596-020-00514-x
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2655275-9
    detail.hit.zdb_id: 3038145-9
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