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  • 1
    Online Resource
    Online Resource
    Enrichment and identification of cyclized hopanoids from Shengli lignite
    Elsevier BV ; 2015
    In:  Fuel Processing Technology Vol. 134 ( 2015-06), p. 399-403
    Details
    In: Fuel Processing Technology, Elsevier BV, Vol. 134 ( 2015-06), p. 399-403
    Type of Medium: Online Resource
    ISSN: 0378-3820
    URL: Article
    DOI: 10.1016/j.fuproc.2015.02.022
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2015
    detail.hit.zdb_id: 1483666-X
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  • 2
    Online Resource
    Online Resource
    Data_Sheet_1.docx
    Frontiers Media SA ; 2022
    In:  Frontiers in Medicine Vol. 8 ( 2022-1-3)
    Details
    In: Frontiers in Medicine, Frontiers Media SA, Vol. 8 ( 2022-1-3)
    Abstract: Backgrounds: Anticoagulation in sepsis-associated disseminated intravascular coagulation (DIC) remains uncertain. The aim of this study was to investigate whether unfractioned heparin (UFH) could improve clinical outcomes in patients with sepsis-induced coagulopathy (SIC). Methods: Septic patients with SIC were identified from the Medical Information Mart for Intensive Care (MIMIC)-III database. Cox-proportional hazards model, logistic regression model and linear regression were used to assess the associations between UFH administration and 28-day mortality, hospital mortality, occurrence of bleeding complications and length of stay, respectively. Propensity score matching (PSM) analysis was used to match the imbalance between patients in the UFH group and the control group. Patients were further stratified according to SIC score and Simplified Acute Physiology Score II (SAPS II). Results: A total of 1,820 septic patients with SIC were included in the data analysis. After PSM, 652 pairs of patients were matched between the patients in the UFH group and the control group. UFH was significantly associated with reduced 28-day mortality (HR, 0.323, 95% CI, 0.258–0.406; p & lt; 0.001) and hospital mortality (HR, 0.380, 95% CI, 0.307–0.472; p & lt; 0.001) without increasing the risks of intracranial hemorrhage (OR, 1.480, 95% CI, 0.955–2.294; p = 0.080) or gastrointestinal bleeding (OR, 1.094, 95% CI, 0.503–2.382; p = 0.820). For subgroup analysis, it didn't change the favorable results of UFH on mortality and UFH didn't increase the risk of hemorrhage in patients with severe disease. Conclusions: The analysis of MIMIC-III database indicated that anticoagulant therapy with UFH may be associated with a survival benefit in patients with SIC.
    Type of Medium: Online Resource
    ISSN: 2296-858X
    URL: Article
    URL: Article
    DOI: 10.3389/fmed.2021.773339
    DOI: 10.3389/fmed.2021.773339.s001
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2775999-4
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  • 3
    Online Resource
    Online Resource
    Usefulness of procalcitonin clearance to predict mortality in abdominal sepsis
    SAGE Publications ; 2020
    In:  European Journal of Inflammation Vol. 18 ( 2020-01), p. 205873922094263-
    Details
    In: European Journal of Inflammation, SAGE Publications, Vol. 18 ( 2020-01), p. 205873922094263-
    Abstract: To evaluate the plasma levels and clearance of procalcitonin (PCTc) as prognostic biomarkers for patients with abdominal sepsis. A retrospective study of 103 patients with abdominal sepsis was conducted in our intensive care unit (ICU) from 2016 to 2018. Procalcitonin (PCT) plasma levels were measured at the time of diagnosis of abdominal sepsis and daily over the next 5 days. PCTc was calculated from day 3 to day 5. The prognostic accuracy of PCTc was expressed as the area under the receiver operating characteristic curve (AUROC). The Kaplan–Meier method was used to compare the survival curves by log-rank test. Logistic regression analysis was used to predict the 28-day mortality. The primary outcome was 28-day mortality since admission to ICU. Serum PCT levels from day 1 to day 5 did not differ significantly between survivors and non-survivors, while PCTc on day 5 was statistically significantly higher in survivors than that in non-survivors (86.4% vs 38.7%, P  〈  0.001). The cutoff value for PCTc-day 5 was 70%, with AUROC of 0.726, sensitivity of 64.6%, and specificity of 78.3%. The 28-day mortality was significantly lower among those with PCTc-day 5 〉 70% compared with those with PCTc-day 5 〈 70% (9.1% vs 38.3%, log-rank test, P  〈  0.001), and odds ratio (OR) was 0.16 (95% confidence interval (CI): 0.05–0.48, P  〈  0.001). The ability to decrease PCT by at least 70% on day 5 was an independent predictor of 28-day mortality after admission to ICU with moderate accuracy.
    Type of Medium: Online Resource
    ISSN: 2058-7392 , 2058-7392
    URL: Article
    DOI: 10.1177/2058739220942631
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2584683-8
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  • 4
    Online Resource
    Online Resource
    Isolation and Identification of Two Novel Condensed Aromatic Lactones from Zhundong Subbituminous Coal
    American Chemical Society (ACS) ; 2014
    In:  Energy & Fuels Vol. 28, No. 12 ( 2014-12-18), p. 7394-7397
    Details
    In: Energy & Fuels, American Chemical Society (ACS), Vol. 28, No. 12 ( 2014-12-18), p. 7394-7397
    Type of Medium: Online Resource
    ISSN: 0887-0624 , 1520-5029
    URL: Article
    DOI: 10.1021/ef501851y
    Language: English
    Publisher: American Chemical Society (ACS)
    Publication Date: 2014
    detail.hit.zdb_id: 1483539-3
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  • 5
    Online Resource
    Online Resource
    Development and validation of a nomogram to predict the risk of renal replacement therapy among acute kidney injury patients in intensive care unit
    Springer Science and Business Media LLC ; 2023
    In:  Clinical and Experimental Nephrology
    Details
    In: Clinical and Experimental Nephrology, Springer Science and Business Media LLC
    Abstract: There are no universally accepted indications to initiate renal replacement therapy (RRT) among patients with acute kidney injury (AKI). This study aimed to develop a nomogram to predict the risk of RRT among AKI patients in intensive care unit (ICU). Methods In this retrospective cohort study, we extracted AKI patients from Medical Information Mart for Intensive Care III (MIMIC-III) database. Patients were randomly divided into a training cohort (70%) and a validation cohort (30%). Multivariable logistic regression based on Akaike information criterion was used to establish the nomogram. The discrimination and calibration of the nomogram were evaluated by Harrell’s concordance index ( C -index) and Hosmer–Lemeshow (HL) test. Decision curve analysis (DCA) was performed to evaluate clinical application. Results A total of 7413 critically ill patients with AKI were finally enrolled. 514 (6.9%) patients received RRT after ICU admission. 5194 (70%) patients were in the training cohort and 2219 (30%) patients were in the validation cohort. Nine variables, namely, age, hemoglobin, creatinine, blood urea nitrogen and lactate at AKI detection, comorbidity of congestive heart failure, AKI stage, and vasopressor use were included in the nomogram. The predictive model demonstrated satisfying discrimination and calibration with C -index of 0.938 (95% CI, 0.927–0.949; HL test, P  = 0.430) in training set and 0.935 (95% CI, 0.919–0.951; HL test, P  = 0.392) in validation set. DCA showed a positive net benefit of our nomogram. Conclusion The nomogram developed in this study was highly accurate for RRT prediction with potential application value.
    Type of Medium: Online Resource
    ISSN: 1342-1751 , 1437-7799
    URL: Article
    DOI: 10.1007/s10157-023-02383-5
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 1499111-1
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  • 6
    Online Resource
    Online Resource
    Effect of oral simethicone on the quality of colonoscopy: A systematic review and meta‐analysis of randomized controlled trials
    Wiley ; 2022
    In:  Journal of Digestive Diseases Vol. 23, No. 3 ( 2022-03), p. 134-148
    Details
    In: Journal of Digestive Diseases, Wiley, Vol. 23, No. 3 ( 2022-03), p. 134-148
    Abstract: In this systematic review and meta‐analysis, we aimed to investigate the effect of oral simethicone (SIM), an antifoaming agent, on the quality of colonoscopy in terms of bowel preparation quality, adenoma or polyp detection rate (ADR/PDR) and cecal intubation rate (CIR). Methods All randomized controlled trials (RCTs) on the use of SIM during bowel preparation for colonoscopy published up to 17 March 2021 were identified from the PubMed, EMBASE and Cochrane Library databases. Bowel preparation quality, ADR/PDR/CIR, cecal intubation time (CIT), withdrawal time (WT), patients' tolerability, acceptability and volume of foam and bubbles were compared between the SIM and non‐SIM groups. Results Thirty‐eight RCTs with 10 505 patients were included. Oral SIM significantly increased the rate of total Boston bowel preparation scale (BBPS) score ≥6 (risk ratio [RR]  1.13, P   〈  0.0001), acceptability (RR  1.15, P  = 0.01) and the rate of no or minimal foam and bubbles (RR  1.28, P   〈  0.00001) and decreased abdominal distension (RR  0.64, P   〈  0.0001). However, it had no significant impact on overall ADR, overall PDR, CIR, CIT or WT. The rate of total BBPS score ≥6 remained significantly higher in the SIM group when a single‐dose laxative regimen or a SIM dosage of ≥320 mg was employed; and ADR, PDR and CIR were significantly increased in the SIM group among colonoscopy clinicians who achieved an ADR 〈 31%, PDR 〈 45% and CIR 〈 96%, respectively. Conclusions Oral SIM can improve bowel preparation quality, especially in patients receiving a SIM dosage of ≥320 mg or a single‐dose laxative regimen. SIM may be preferred by junior colonoscopy physicians/trainees with a lower ADR/PDR or CIR.
    Type of Medium: Online Resource
    ISSN: 1751-2972 , 1751-2980
    URL: Issue
    URL: Article
    DOI: 10.1111/cdd.v23.3
    DOI: 10.1111/1751-2980.13084
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2317117-0
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  • 7
    Online Resource
    Online Resource
    Overexpression of the ChVDE gene, encoding a violaxanthin de-epoxidase, improves tolerance to drought and salt stress in transgenic Arabidopsis
    Springer Science and Business Media LLC ; 2019
    In:  3 Biotech Vol. 9, No. 5 ( 2019-5)
    Details
    In: 3 Biotech, Springer Science and Business Media LLC, Vol. 9, No. 5 ( 2019-5)
    Type of Medium: Online Resource
    ISSN: 2190-572X , 2190-5738
    URL: Article
    DOI: 10.1007/s13205-019-1732-6
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 2600522-0
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  • 8
    Online Resource
    Online Resource
    A Fully Digital Beam Position and Phase Measurement Electronics for the Proton LINAC in ADS
    Trans Tech Publications, Ltd. ; 2013
    In:  Applied Mechanics and Materials Vol. 333-335 ( 2013-7), p. 379-388
    Details
    In: Applied Mechanics and Materials, Trans Tech Publications, Ltd., Vol. 333-335 ( 2013-7), p. 379-388
    Abstract: The beam measurement is essential for an accelerator. In the proton LINAC in China Accelerator Driven Sub-critical system (ADS), a high resolution measurement of beam position and phase is required within one single system. To meet the requirement, this beam position and phase measurement (BPPM) electronics is designed based on a direct RF under-sampling technique, which simplifies both the analog and digital processing circuits. The signals received from the LINAC are narrow pulses with a repetition frequency of 162.5 MHz and a dynamic range more than 40 dB. After analog manipulation, the input RF signals are directly converted to In-phase and Quadrature-phase (IQ) streams through under-sampling based on the high-speed high-resolution Analog-to-Digital conversion technique. All signal processing is integrated in one single FPGA, in which real-time beam position, phase and current can be obtained. A series of simulations and tests have been conducted to evaluate the performance. Initial test results indicate that this system achieves a position resolution better than 20 um and a phase resolution better than 0.1 degree over a 40 dB dynamic range with the bandwidth of 780 kHz, which is well beyond the application requirements.
    Type of Medium: Online Resource
    ISSN: 1662-7482
    URL: Issue
    URL: Article
    DOI: 10.4028/www.scientific.net/AMM.333-335
    DOI: 10.4028/www.scientific.net/AMM.333-335.379
    Language: Unknown
    Publisher: Trans Tech Publications, Ltd.
    Publication Date: 2013
    detail.hit.zdb_id: 2251882-4
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  • 9
    Online Resource
    Online Resource
    Design of "Software Engineering" Teaching Website
    Trans Tech Publications, Ltd. ; 2013
    In:  Advanced Materials Research Vol. 651 ( 2013-1), p. 802-806
    Details
    In: Advanced Materials Research, Trans Tech Publications, Ltd., Vol. 651 ( 2013-1), p. 802-806
    Abstract: "software engineering" is different from the general professional courses, it is born for getting rid of the software crisis and adapting to the development of software industry, it is a theory course, especially a practical course. However, due to the own characteristics of software engineering curriculum, in the daily teaching process, concerning theoretical study, students may feel boring, obtain low interest in learning and poor test results and other problems. ASPNET design technique is adopted and Access 2007 database is used for system to design and realize "Software Engineering" teaching website. System features mainly include theoretical teaching, case teaching, practical teaching, teaching interaction, database, test item bank, announcement, etc., which can enhance the vitality, interest and dynamic role of learning.
    Type of Medium: Online Resource
    ISSN: 1662-8985
    URL: Issue
    URL: Article
    DOI: 10.4028/www.scientific.net/AMR.651
    DOI: 10.4028/www.scientific.net/AMR.651.802
    Language: Unknown
    Publisher: Trans Tech Publications, Ltd.
    Publication Date: 2013
    detail.hit.zdb_id: 2265002-7
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  • 10
    Online Resource
    Online Resource
    The efficacy of extracorporeal membrane oxygenation in liver transplantation from non-heart-beating donors : A systemic review and meta-analysis
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  Medicine Vol. 98, No. 9 ( 2019-03), p. e14722-
    Details
    In: Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 98, No. 9 ( 2019-03), p. e14722-
    Abstract: A systematic review and meta-analysis was made to see whether extracorporeal membrane oxygenation (ECMO) in liver transplantation could improve non-heart-beating donors (NHBDs) recipients’ outcomes compared with donors after brain death (DBDs) recipients. Methods: We searched MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials for eligible studies. The study eligible criteria are cohort or case–control studies using ECMO in all NHBDs; studies involved a comparison group of DBDs; and studies evaluated 1-year graft and patient survival rate in NHBDs and DBDs groups. Results: Four studies with 704 patients fulfilled the inclusion criteria. The pooled odds ratio (OR) of 1-year patient survival rate in NHBDs recipients compared with DBDs recipients was 0.8 (95% confidence interval [CI], 0.41–1.55). The pooled OR of 1-year graft survival rate in NHBDs recipients compared with DBDs recipients was 0.46 (95% CI, 0.26–0.81). NHBDs recipients were at greater risks to the occurrence of primary nonfunction (PNF) (OR = 7.12, 95% CI, 1.84–27.52) and ischemic cholangiopathy (IC) (OR = 9.46, 95% CI, 2.76–32.4) than DBDs recipients. Conclusions: ECMO makes 1-year patient survival acceptable in NHBDs recipients. One-year graft survival rate was lower in NHBDs recipients than in DBDs recipients. Compared with DBDs recipients, the risks to develop PNF and IC were increased among NHBDs recipients.
    Type of Medium: Online Resource
    ISSN: 0025-7974 , 1536-5964
    URL: Article
    DOI: 10.1097/MD.0000000000014722
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2019
    detail.hit.zdb_id: 2049818-4
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