In:
Journal of Biological Engineering, Springer Science and Business Media LLC, Vol. 6, No. 1 ( 2012-12)
Abstract:
Synthetic biology is an emerging field that combines molecular biology with engineering principles, which requires abstraction levels applied to a modular biological componentry. The Registry of Standard Biological Parts harbours such a repository of standardized parts, and thereby facilitates the combination of complex molecular modules to novel genetic circuits and devices. However, since finding the best parts for a pre-determined genetic design can be time consuming, we devised the Constructor, a web tool that recommends the smallest number of cloning steps for pre-designed circuits, and implements user-defined quality checks. We present the Constructor ( http://www.systemsbiology.nl/the_constructor ) as a constructive web tool that simplifies the in silico assembly of pre-designed gene circuitries from standard parts, reducing both planning and subsequent cloning time.
Type of Medium:
Online Resource
ISSN:
1754-1611
DOI:
10.1186/1754-1611-6-14
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2012
detail.hit.zdb_id:
2391582-1
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