In:
European Neurology, S. Karger AG, Vol. 53, No. 2 ( 2005), p. 81-83
Abstract:
〈 i 〉 Chlamydophila pneumoniae 〈 /i 〉 has been proposed as an aetiological agent in MS via a mechanism involving molecular mimicry. We undertook to investigate whether the presence of CSF oligoclonal IgG OCB or oligoclonal bands correlated with serum IgG raised against 〈 i 〉 C. pneumoniae 〈 /i 〉 . Paired serum and CSF of 19 MS patients and 27 control patients with other neurological diseases were studied by IEF and Western blotting. Only 1 of 19 MS patients had serum antibodies against 〈 i 〉 C. pneumoniae 〈 /i 〉 compared with 2 of the 26 control patients. This was not significant, leading us to conclude that this study does not support the theory of an association between 〈 i 〉 C. pneumoniae 〈 /i 〉 and MS.
Type of Medium:
Online Resource
ISSN:
0014-3022
,
1421-9913
Language:
English
Publisher:
S. Karger AG
Publication Date:
2005
detail.hit.zdb_id:
1482237-4
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