In:
Respirology, Wiley, Vol. 12, No. 5 ( 2007-09), p. 707-711
Abstract:
Background and objective: This study reports on the demographic features, clinico‐pathological results and prognoses of patients aged less than 36 years diagnosed with non‐small cell lung cancer (NSCLC). Methods: This is an observational study of patients with primary NSCLC who had a surgical procedure at a tertiary thoracic surgery centre in Turkey. Data collected were age, gender, history of smoking, symptoms, postoperative histopathological diagnosis, stage, surgical procedure and survival. Results: Of the 31 patients in the study, 27 were male (87%) and the median age was 32 years (10–35 years). Nineteen patients were smokers (61.2%). The most common presenting symptom was cough ( n = 23, 67.7%). Histopathological diagnosis was squamous cell carcinoma (SCC, n = 17), adenocarcinoma ( n = 12), lymphoepithelioma‐like carcinoma ( n = 1) and undifferentiated carcinoma ( n = 1). Staging of the 17 patients with SCC (58.8%) was stage I and II ( n = 10, 58%), and stage III ( n = 7, 41%). Staging of the 13 patients with adenocarcinoma was stage IV ( n = 2, 16%) and stage III patients ( n = 8, 66%). Follow‐up data were available on 22 patients (71%) and showed a median survival of 17.2 months. Two and 5‐year survival rates were 54.5% and 45.5%, respectively. Conclusions: SCC comprised a relatively high proportion of NSCLC in these younger patients. Aggressive multimodality treatment may achieve satisfactory 2‐ and 5‐year survival rates in young patients with NSCLC who usually present with advanced disease.
Type of Medium:
Online Resource
ISSN:
1323-7799
,
1440-1843
DOI:
10.1111/res.2007.12.issue-5
DOI:
10.1111/j.1440-1843.2007.01137.x
Language:
English
Publisher:
Wiley
Publication Date:
2007
detail.hit.zdb_id:
2010720-1
detail.hit.zdb_id:
1435849-9
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