In:
Annals of Clinical and Translational Neurology, Wiley, Vol. 5, No. 9 ( 2018-09), p. 1104-1111
Abstract:
Primary intraventricular hemorrhage ( pIVH ) uncommonly presents with seizures. There are no prior data regarding the frequency of seizures, periodic and rhythmic patterns on continuous electroencephalography (EEG), ( cEEG ) in these patients. Methods We retrospectively assessed frequency of seizures, periodic discharges, and rhythmic patterns in pIVH patients undergoing cEEG monitoring. We reviewed indications for cEEG , demographics, GCS at presentation and during cEEG , modified Graeb score ( mGS ), presence of hydrocephalus, cEEG duration, findings and use of antiseizure medications ( ASM ). cEEG patterns were classified according to location and morphology. All patterns were considered “hyperexcitable” except GRDA . The ictal‐interictal continuum ( IIC ) was defined as LRDA , PD s, and/or SW 〉 1 Hz but 〈 2.5 Hz, not meeting criteria for definite electrographic seizures. Results Eleven patients had pIVH with median age of 81 (46–87) years and median mGS of 15 (9–23). Hydrocephalus was present in 7 (63.6%) and all underwent external ventricular drain ( EVD ) placement. Median cEEG recording was 19 (12–156) hours. Periodic or rhythmic EEG patterns were seen in 7 of 11 (64%), 5 of which were “hyperexcitable”. For the 5 patients with pIVH , EVD s, and hyperexcitable patterns, 4 (80%) were lateralized contralateral to the EVD and 1 (20%) was generalized to the EVD . The only significant difference between the hyperexcitable and non‐hyperexcitable group was duration of cEEG monitoring ( P = 0.007). Interpretation Hyperexcitable patterns were common in our cases. Further research is warranted to assess prevalence of hyperexcitable patterns, their risk factors, underlying pathophysiology, and association with neuronal injury in pIVH .
Type of Medium:
Online Resource
ISSN:
2328-9503
,
2328-9503
DOI:
10.1002/acn3.2018.5.issue-9
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2740696-9
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