GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 11
    Online Resource
    Online Resource
    Feasibility Analysis of Importing PHA instead of PE in Singapore
    Darcy & Roy Press Co. Ltd. ; 2023
    In:  Academic Journal of Science and Technology Vol. 7, No. 2 ( 2023-09-27), p. 10-18
    Details
    In: Academic Journal of Science and Technology, Darcy & Roy Press Co. Ltd., Vol. 7, No. 2 ( 2023-09-27), p. 10-18
    Abstract: This article presents a comprehensive examination of Singapore's thriving service and transportation sectors, with a particular focus on the increasing demand for packaging and disposable goods. The subsequent heavy reliance on polyethylene (PE) is emphasized. Subsequently, the article delves into the ecological consequences associated with the widespread use of PE in Singapore. This encompasses considerations such as ecological space occupancy, plastic pollution, and greenhouse gas emissions. In response to these pressing challenges, the article suggests practical solutions. With a strong emphasis on environmental concerns, the article promotes the adoption of polyhydroxyalkanoates (PHA) as a feasible and eco-friendly alternative to the environmentally detrimental PE. This proposal is juxtaposed with a comprehensive comparative analysis of other renewable materials like polylactic acid (PLA) and PHA, critically evaluating their innovative potential and inherent limitations. To ensure the successful implementation of the proposed solutions, the article presents a diverse range of resource management strategies. Additionally, the article outlines a clear pathway for transitioning and upgrading Singapore's existing polyethylene products. It offers well-founded explanations and recommendations for advancing industries while comparing the feasibility, financial aspects, transformation challenges, and strategies between the LDPE and PHA sectors. The article culminates in a meticulous simulation that calculates the financial requirements for a complete shift from PE to PHA in Singapore by 2021, along with the subsequent cost implications for the packaging industry. These rigorous analyses and calculations provide precise quantitative guidance, aiding policymakers, entrepreneurs, and decision-makers in making well-informed decisions for transformative initiatives.
    Type of Medium: Online Resource
    ISSN: 2771-3032
    URL: Article
    DOI: 10.54097/ajst.v7i2.11513
    Language: Unknown
    Publisher: Darcy & Roy Press Co. Ltd.
    Publication Date: 2023
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 12
    Online Resource
    Online Resource
    YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas
    Springer Science and Business Media LLC ; 2021
    In:  Cancer Cell International Vol. 21, No. 1 ( 2021-12)
    Details
    In: Cancer Cell International, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2021-12)
    Abstract: Autophagy is a double-edged sword during the initiation and progression of multiple tumors. The Hippo pathway effector YAP has been proved to be involved in autophagy processes. The present study aimed to investigate how YAP regulates cell proliferation via autophagy in lung adenocarcinomas (LUAD). Methods Data of LUAD chip GSE43458 was obtained from Gene Expression Omnibus (GEO). RT-qPCR and Western blot were performed to assess YAP expression in LUAD cell lines. CCK-8 assay, xenograft tumor model, immunochemistry and GFP-mRFP-LC3 fusion proteins were utilized to evaluate the effect of YAP on autophagy of LUAD cells in vitro and in vivo . Autophagy inhibitor treatment and rescue experiments were carried out to elucidate the mechanism by which YAP manipulates autophagy in LUAD cells. Results YAP was significantly overexpressed in samples of LUAD patients and its expression level is related to 5-year survival. YAP manipulated the proliferation and autophagy in A549 and H1299 LUAD cells. YAP could induce activation of Akt/mTOR signaling pathway via suppressing PTEN in a Hippo-pathway-dependent manner. 3-Methyladenine impeded autophagy flux and promoted the proliferation in vitro and in vivo . Conclusions Hippo pathway critical transcriptional coactivators YAP manipulates the proliferation of lung adenocarcinoma, which is regulated by PTEN/AKT/mTOR autophagic signaling.
    Type of Medium: Online Resource
    ISSN: 1475-2867
    URL: Article
    DOI: 10.1186/s12935-020-01688-9
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2091573-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 13
    Online Resource
    Online Resource
    Lower circulating irisin levels in type 2 diabetes mellitus patients with chronic complications: A meta-analysis
    Elsevier BV ; 2023
    In:  Heliyon Vol. 9, No. 11 ( 2023-11), p. e21859-
    Details
    In: Heliyon, Elsevier BV, Vol. 9, No. 11 ( 2023-11), p. e21859-
    Type of Medium: Online Resource
    ISSN: 2405-8440
    URL: Article
    DOI: 10.1016/j.heliyon.2023.e21859
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2835763-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 14
    Online Resource
    Online Resource
    Alkaline metal derived secondary thermal polymerization for superior thin g-C3N4 nanosheets with efficient photocatalytic performance
    Elsevier BV ; 2023
    In:  International Journal of Hydrogen Energy ( 2023-7)
    Details
    In: International Journal of Hydrogen Energy, Elsevier BV, ( 2023-7)
    Type of Medium: Online Resource
    ISSN: 0360-3199
    URL: Article
    DOI: 10.1016/j.ijhydene.2023.06.237
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 1484487-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 15
    Online Resource
    Online Resource
    Genome-Wide Investigation of Spliceosomal SM/LSM Genes in Wheat (Triticum aestivum L.) and Its Progenitors
    MDPI AG ; 2021
    In:  Agronomy Vol. 11, No. 7 ( 2021-07-17), p. 1429-
    Details
    In: Agronomy, MDPI AG, Vol. 11, No. 7 ( 2021-07-17), p. 1429-
    Abstract: The SSM/SLSM (spliceosomal Smith (SM)/SM-like (LSM)) genes are the central components of the spliceosome in eukaryotes, which play an important role in regulating RNA splicing, participating in diverse biological processes. Although it has been detected in Arabidopsis and rice etc. plants, the members and significance of the SSM/SLSM gene family in wheat are still not reported. In this study, we identified the SSM/SLSM genes in wheat and its progenitors at genome-scale, where 57 SSM/SLSM genes were identified in wheat, together with 41, 17and 19 found in Triticum dicoccoides, Triticum urartu, and Aegilops tauschii. Furthermore, their phylogenetic relationship, gene structures, conserved motifs, and cis-regulatory elements were systematically analyzed. By synteny analysis, good collinearity of SSM/SLSM genes was found among bread wheat and its progenitors’ genomes, and the distribution of SMD2 genes in wheat chromosome 5A, 4B and 4D located in the 4AL-5AL-7BS chromosome model, due to the translocation. Then, the positively selected genes were further investigated based on the non-synonymous to synonymous (dN/dS) analysis of the orthologous pairs. Finally, the expression profiles of the SSM/SLSM genes were detected using RNA-seq datasets, and eight stress-responsive candidate genes were selected to validate their expression through qPCR (real-time quantitative polymerase chain reaction). According to the co-expression network analysis, the correlation between the LSM7-7A gene and related genes was illustrated through Gene Ontology (GO) enrichment analysis. Furthermore, the LSM7-7A gene was related to the Arabidopsis homologous salt tolerance gene RCY1. This investigation systematically identified the complete candidates of SSM/SLSM genes and their characters in wheat and its progenitors, and provided clues to a better understanding of their contribution during the wheat polyploidy process.
    Type of Medium: Online Resource
    ISSN: 2073-4395
    URL: Article
    DOI: 10.3390/agronomy11071429
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2607043-1
    SSG: 23
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 16
    Online Resource
    Online Resource
    Silicate Ions Derived from Calcium Silicate Extract Decelerate Ang II-Induced Cardiac Remodeling
    Springer Science and Business Media LLC ; 2023
    In:  Tissue Engineering and Regenerative Medicine Vol. 20, No. 5 ( 2023-08), p. 671-681
    Details
    In: Tissue Engineering and Regenerative Medicine, Springer Science and Business Media LLC, Vol. 20, No. 5 ( 2023-08), p. 671-681
    Type of Medium: Online Resource
    ISSN: 1738-2696 , 2212-5469
    URL: Article
    DOI: 10.1007/s13770-023-00523-2
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2677535-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 17
    Online Resource
    Online Resource
    Soil depth alters the effect of species diversity on productivity in an experimental karst herbaceous community
    Springer Science and Business Media LLC ; 2022
    In:  Plant and Soil Vol. 471, No. 1-2 ( 2022-02), p. 61-71
    Details
    In: Plant and Soil, Springer Science and Business Media LLC, Vol. 471, No. 1-2 ( 2022-02), p. 61-71
    Type of Medium: Online Resource
    ISSN: 0032-079X , 1573-5036
    URL: Article
    DOI: 10.1007/s11104-021-05095-5
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 1478535-3
    detail.hit.zdb_id: 208908-7
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 18
    Online Resource
    Online Resource
    Haplotype‐based non‐invasive prenatal diagnosis of recessive dystrophic epidermolysis bullosa via targeted capture sequencing of maternal plasma
    Wiley ; 2023
    In:  The Journal of Dermatology Vol. 50, No. 7 ( 2023-07), p. 946-950
    Details
    In: The Journal of Dermatology, Wiley, Vol. 50, No. 7 ( 2023-07), p. 946-950
    Abstract: Recessive dystrophic epidermolysis bullosa (RDEB) is a rare and severe hereditary skin disease, caused by mutations in the COL7A1 . However, whether non‐invasive prenatal testing (NIPT) can be used for this monogenic genodermatosis remains unknown. Accordingly, we conducted a study in which one couple at high risk of having a fetus with RDEB were recruited and tested by haplotyping‐based NIPT. Next‐generation sequencing‐based multi‐gene panel testing was carried out in this couple and their first child as proband who was affected with RDEB. We deduced parental haplotypes via single nucleotide polymorphism (SNP)‐based haplotype linkage analysis. Then the maternal plasma cell‐free DNA was also sequenced to determine the fetal haplotypes using a parental haplotype‐assisted hidden Markov model (HMM) analysis. Results show that the fetus was only a heterozygous mutation carrier in COL7A1 and the identical results were obtained after birth. These results demonstrate that haplotyping‐based NIPT is a feasible method for NIPT of RDEB.
    Type of Medium: Online Resource
    ISSN: 0385-2407 , 1346-8138
    URL: Issue
    URL: Article
    DOI: 10.1111/jde.v50.7
    DOI: 10.1111/1346-8138.16760
    RVK:
    XA 53120
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2222121-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 19
    Online Resource
    Online Resource
    Preparation and Characterization of 3D Printed Porous 45S5 Bioglass Bioceramic for Bone Tissue Engineering Application
    AccScience Publishing ; 2022
    In:  International Journal of Bioprinting Vol. 8, No. 4 ( 2022-09-01), p. 613-
    Details
    In: International Journal of Bioprinting, AccScience Publishing, Vol. 8, No. 4 ( 2022-09-01), p. 613-
    Abstract: Three-dimensional (3D) printing technology provides advanced technical support for designing personalized bone tissue engineering scaffold. In this study, two porous diffusing models, namely, average and layered perforated cylindrical scaffolds, were designed for bone tissue engineering scaffold. The designed models were fabricated by liquid crystal display mask stereolithography printing. Structural design and finite element mechanical analysis were conducted. 45S5 bioglass was selected as the raw material for preparing the printing inks for bone tissue engineering scaffolds. By adjusting the viscosity and temperature of the slurry, the maximum proportion of 45S5 bioglass (40 wt%) was added into the photosensitive resin for preparing 3D printing slurry. Our results indicated that an optimized sintering condition includes the debinding rate (0.5 & deg;C/ min), and temperature raising rate (5 & deg;C/min) and sintering temperature (1100 & deg;C) were proposed to sinter 45S5 bioceramic scaffolds. The amorphous 45S5 bioglass showed good crystallization after sintering, and the scaffold porous structure showed good integrity. Micropores were observed in the struts which interconnected with each other. Moreover, the porosities were tested as 57% and 45% with a uniform pore distribution. The shrinkage rate was about 10% during sintering process due to binder burning and crystallization shrinkage. The compressive strength of the sintered scaffold was 0.71 & plusmn; 0.048 MPa and 2.13 & plusmn; 0.054 MPa, respectively, which are consistent with the finite element mechanical analysis simulation results. In conclusion, the layered perforated 45S5 bioglass scaffold shows good mechanical properties and porosity, indicating that it could be a promising candidate for bone tissue engineering.
    Type of Medium: Online Resource
    ISSN: 2424-7723 , 2424-8002
    URL: Article
    DOI: 10.18063/ijb.v8i4.613
    Language: Unknown
    Publisher: AccScience Publishing
    Publication Date: 2022
    detail.hit.zdb_id: 2834694-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 20
    Online Resource
    Online Resource
    Diet Restriction Impact on High-Fat-Diet-Induced Obesity by Regulating Mitochondrial Cardiolipin Biosynthesis and Remodeling
    MDPI AG ; 2023
    In:  Molecules Vol. 28, No. 11 ( 2023-06-02), p. 4522-
    Details
    In: Molecules, MDPI AG, Vol. 28, No. 11 ( 2023-06-02), p. 4522-
    Abstract: Diet restriction (DR) ameliorates obesity by regulating mitochondrial function. Cardiolipin (CL), a mitochondrial phospholipid, is closely associated with mitochondrial function. This study aimed to evaluate the anti-obesity effects of graded levels of DR based on mitochondrial CL levels in the liver. Obese mice were treated with 0%, 20%, 40%, and 60% reductions in the normal diet compared to normal animals (0 DR, 20 DR, 40 DR, and 60 DR groups, respectively). Biochemical and histopathological analyses were performed to evaluate the ameliorative effects of DR on obese mice. The altered profile of mitochondrial CL in the liver was explored using a targeted metabolomics strategy by ultra-high-pressure liquid chromatography MS/MS coupled with quadrupole time-of-flight mass spectrometry. Finally, gene expression associated with CL biosynthesis and remodeling was quantified. Tissue histopathology and biochemical index evaluations revealed significant improvements in the liver after DR, except for the 60 DR group. The variation in mitochondrial CL distribution and DR levels showed an inverted U-shape, and the CL content in the 40 DR group was the most upregulated. This result is consistent with the results of the target metabolomic analysis, which showed that 40 DR presented more variation. Furthermore, DR led to increased gene expression associated with CL biosynthesis and remodeling. This study provides new insights into the mitochondrial mechanisms underlying DR intervention in obesity.
    Type of Medium: Online Resource
    ISSN: 1420-3049
    URL: Article
    DOI: 10.3390/molecules28114522
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2008644-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...