In:
GLOBAL JOURNAL FOR RESEARCH ANALYSIS, World Wide Journals
Abstract:
Leukocyte adhesion defect (LAD) is a rare, autosomal recessive primary immunodeficiency disorder of phagocytes, in which there is defective aggregation at the site of infection due to the absence of surface integrins. Diagnosis is based primarily on flowcytometric analysis of neutrophils for the surface expression of CD11, CD18 and CD15s. We describe here a case series of 3 children presented to us within a period of one year and diagnosed as LAD. Diagnosis was made on the basis of clinical features and simple laboratory investigations.
Type of Medium:
Online Resource
DOI:
10.36106/gjra/8614228
Language:
English
Publisher:
World Wide Journals
Publication Date:
2020
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