In:
Canadian Journal of Chemistry, Canadian Science Publishing, Vol. 63, No. 11 ( 1985-11-01), p. 2853-2860
Abstract:
The synthetic route to 6-chloromercuricholest-5-en-3β-ol has been studied and the yield improved from 2% to 20%. The reaction of 6-chloromercuricholest-5-en-β-ol with fluorine, chlorine, bromine, and iodine has been examined. 6-Bromocholest-5-en-3β-ol and 6-chlorocholest-5-en-3β-ol have been directly prepared from 6-iodocholest-5-en-3β-ol using cuprous halides. A new intermediate, 6-tosyloxycholest-5-en-3β-ol, has also been synthesized by the action of silver tosylate on 6-iodocholest-5-en-3β-ol. The structures of the compounds were proven by a combination of high-resolution 1 Hmr and 13 Cmr. A new crystal modification of 6-chloromercuricholest-5-en-3β-ol has been found.
Type of Medium:
Online Resource
ISSN:
0008-4042
,
1480-3291
Language:
English
Publisher:
Canadian Science Publishing
Publication Date:
1985
detail.hit.zdb_id:
1482256-8
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