In:
Otology & Neurotology, Ovid Technologies (Wolters Kluwer Health), Vol. 39, No. 5 ( 2018-06), p. e381-e386
Abstract:
The aim of this study was to compare the clinical characteristics of cystic vestibular schwannomas (CVSs) and solid vestibular schwannomas (SVSs). Study Design: Retrospective review. Setting: Tertiary care center. Patients: A total of 220 patients who underwent microsurgery for vestibular schwannomas between 2007 and 2016. Intervention: CVSs were defined as cystic components ≥1/3 of total tumor volume based on automated volume measurement. Tumors larger than 5 cm 3 were defined as large tumors. Main Outcome Measures: Clinical characteristics and surgical outcomes, including preoperative symptoms, hearing threshold, vestibular function, tumor volume, extent of resection, facial nerve outcomes, and nonfacial complications were evaluated. Results: Tumor volume was significantly larger in CVSs (20.44 ± 13.85 cm 3 in CVSs; 4.75 ± 6.48 cm 3 in SVSs, p 〈 0.001) and the proportion of larger tumors was also greater in CVSs (66.0% in CVSs; 11.4% in SVSs, p 〈 0.001). Preoperative dizziness was highly prevalent in CVSs (32.1% in CVSs; 18.6% in SVSs, p = 0.038) and postoperative facial nerve outcomes were significantly worse in CVSs (67.9% favorable rate in CVSs; 87.4% favorable rate in SVSs, p = 0.001). When the comparison was limited to large tumors, no clinical characteristics or surgical outcomes were significantly different. Tumor volume had a greater effect than tumor type on the surgical outcomes. The odds ratios for subtotal resection and unfavorable facial nerve function with a large tumor were 5.77 (confidence interval [CI]: 1.52–21.95, p = 0.010) and 5.34 (CI: 1.41–20.22, p = 0.014), respectively. Conclusion: CVSs tend to be larger than SVSs. Tumor volume, not cystic component, is thought to be a major determinant of surgical outcomes.
Type of Medium:
Online Resource
ISSN:
1531-7129
,
1537-4505
DOI:
10.1097/MAO.0000000000001813
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2018
detail.hit.zdb_id:
2058738-7
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