In:
Journal of Virology, American Society for Microbiology, Vol. 80, No. 12 ( 2006-06-15), p. 5663-5669
Abstract:
Seventy-two
full genomes corresponding to nine mammalian (67 strains) and two avian (5 strains) polyomavirus species were analyzed using maximum likelihood
and Bayesian methods of phylogenetic inference. Our fully resolved and well-supported (bootstrap proportions 〉 90%; posterior
probabilities = 1.0) trees separate the bird polyomaviruses (avian polyomavirus and goose hemorrhagic polyomavirus) from the
mammalian polyomaviruses, which supports the idea of spitting the genus into two subgenera. Such a split is also consistent with the different
viral life strategies of each group. Simian (simian virus 40, simian agent 12 [Sa12], and lymphotropic polyomavirus) and rodent (hamster polyomavirus, mouse polyomavirus, and murine pneumotropic polyomavirus
[MPtV] ) polyomaviruses did not form monophyletic groups. Using our best
hypothesis of polyomavirus evolutionary relationships and established host phylogenies, we performed a cophylogenetic reconciliation analysis
of codivergence. Our analyses generated six optimal cophylogenetic scenarios of coevolution, including 12 codivergence events ( P 〈 0.01), suggesting that Polyomaviridae coevolved with
their avian and mammal hosts. As individual lineages, our analyses showed evidence of host switching in four terminal branches leading to
MPtV, bovine polyomavirus, Sa12, and BK virus, suggesting a combination of vertical and horizontal transfer in the evolutionary history of the
polyomaviruses.
Type of Medium:
Online Resource
ISSN:
0022-538X
,
1098-5514
DOI:
10.1128/JVI.00056-06
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
2006
detail.hit.zdb_id:
1495529-5
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