GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    High rates of microbial dinitrogen fixation and sulfate reduction associated with the Mediterranean seagrass Posidonia oceanica
    Elsevier BV ; 2016
    In:  Systematic and Applied Microbiology Vol. 39, No. 7 ( 2016-10), p. 476-483
    Details
    In: Systematic and Applied Microbiology, Elsevier BV, Vol. 39, No. 7 ( 2016-10), p. 476-483
    Type of Medium: Online Resource
    ISSN: 0723-2020
    URL: Article
    DOI: 10.1016/j.syapm.2016.08.004
    RVK:
    WA 15000
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2016
    detail.hit.zdb_id: 283612-9
    detail.hit.zdb_id: 2046331-5
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Metabolic versatility of a novel N 2 ‐fixing Alphaproteobacterium isolated from a marine oxygen minimum zone
    Wiley ; 2018
    In:  Environmental Microbiology Vol. 20, No. 2 ( 2018-02), p. 755-768
    Details
    In: Environmental Microbiology, Wiley, Vol. 20, No. 2 ( 2018-02), p. 755-768
    Abstract: The N 2 ‐fixing (diazotrophic) community in marine ecosystems is dominated by non‐cyanobacterial microorganisms. Yet, very little is known about their identity, function and ecological relevance due to a lack of cultured representatives. Here we report a novel heterotrophic diazotroph isolated from the oxygen minimum zone (OMZ) off Peru. The new species belongs to the genus Sagittula ( Rhodobacteraceae , Alphaproteobacteria ) and its capability to fix N 2 was confirmed in laboratory experiments. Genome sequencing revealed that it is a strict heterotroph with a high versatility in substrate utilization and energy acquisition mechanisms. Pathways for sulfide oxidation and nitrite reduction to nitrous oxide are encoded in the genome and might explain the presence throughout the Peruvian OMZ. The genome further indicates that this novel organism could be in direct interaction with other microbes or particles. NanoSIMS analyses were used to compare the metabolic potential of S. castanea with single‐cell activity in situ ; however, N 2 fixation by this diazotroph could not be detected at the isolation site. While the biogeochemical impact of S. castanea is yet to be resolved, its abundance and widespread distribution suggests that its potential to contribute to the marine N input could be significant at a larger geographical scale.
    Type of Medium: Online Resource
    ISSN: 1462-2912 , 1462-2920
    URL: Issue
    URL: Article
    DOI: 10.1111/emi.2018.20.issue-2
    DOI: 10.1111/1462-2920.14008
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2020213-1
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Key Intervention Categories to Provide Person-Centered Dementia Care: A Systematic Review of Person-Centered Interventions
    IOS Press ; 2021
    In:  Journal of Alzheimer's Disease Vol. 84, No. 1 ( 2021-10-26), p. 343-366
    Details
    In: Journal of Alzheimer's Disease, IOS Press, Vol. 84, No. 1 ( 2021-10-26), p. 343-366
    Abstract: Background: Person-centered care (PCC) is an important concept in many countries’ national guidelines and dementia plans. Key intervention categories, i.e., a taxonomy of person-centered (PC)-interventions, to provide person-centered dementia care, are difficult to identify from literature. Objective: This systematic review aimed to identify and categorize published PC-interventions into key intervention categories to guide the provision of person-centered dementia care. Methods: Conduct of this systematic review followed Cochrane guidelines. A search of the dimensions ‘Dementia’, ‘Person-Centered Care’, and ‘Intervention’ combined was performed in PubMed, EMBASE, and Web of Science. Study selection was based on 2-stage screening against eligibility criteria, limited to controlled study designs. Information about interventions and outcomes was extracted into an “Effects Table”. The identified PC-interventions were categorized in intervention categories to provide person-centered dementia care. Results: Searches identified 1,806 records. 19 studies were included. These covered a range of psychosocial interventions, oftentimes multi-component interventions, which followed heterogeneous approaches. Studies were conducted in long-term care/hospital settings. Nine key intervention categories were identified: social contact, physical activities, cognitive training, sensory enhancement, daily living assistance, life history oriented emotional support, training and support for professional caregivers, environmental adjustments, and care organization. Conclusion: Our findings provide a current overview of published PC-interventions in dementia, which followed heterogeneous approaches under the PCC-concept. The heterogeneity made it challenging to identify a well-defined concept of PCC and common key intervention categories. An effectiveness-evaluation of “PC” - including “relationship-centered”-interventions may be valuable, to assess whether an explicit focus on relationships around PCC-interventions yields an added benefit. PROSPERO-ID: CRD42021225084.
    Type of Medium: Online Resource
    ISSN: 1387-2877 , 1875-8908
    URL: Article
    DOI: 10.3233/JAD-210647
    Language: Unknown
    Publisher: IOS Press
    Publication Date: 2021
    detail.hit.zdb_id: 2070772-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Prevalence of Low-Value Care and Its Associations with Patient-Centered Outcomes in Dementia
    IOS Press ; 2021
    In:  Journal of Alzheimer's Disease Vol. 83, No. 4 ( 2021-10-12), p. 1775-1787
    Details
    In: Journal of Alzheimer's Disease, IOS Press, Vol. 83, No. 4 ( 2021-10-12), p. 1775-1787
    Abstract: Background: Low-value care (LvC) is defined as care unlikely to provide a benefit to the patient regarding the patient’s preferences, potential harms, costs, or available alternatives. Avoiding LvC and promoting recommended evidence-based treatments, referred to as high-value care (HvC), could improve patient-reported outcomes for people living with dementia (PwD). Objective: This study aims to determine the prevalence of LvC and HvC in dementia and the associations of LvC and HvC with patients’ quality of life and hospitalization. Methods: The analysis was based on data of the DelpHi trial and included 516 PwD. Dementia-specific guidelines, the “Choosing Wisely” campaign and the PRISCUS list were used to indicate LvC and HvC treatments, resulting in 347 LvC and HvC related recommendations. Of these, 77 recommendations (51 for LvC, 26 for HvC) were measured within the DelpHi-trial and finally used for this analysis. The association of LvC and HvC treatments with PwD health-related quality of life (HRQoL) and hospitalization was assessed using multiple regression models. Results: LvC was highly prevalent in PwD (31%). PwD receiving LvC had a significantly lower quality of life (b = –0.07; 95% CI –0.14 – –0.01) and were significantly more likely to be hospitalized (OR = 2.06; 95% CI 1.26–3.39). Different HvC treatments were associated with both positive and negative changes in HRQoL. Conclusion: LvC could cause adverse outcomes and should be identified as early as possible and tried to be replaced. Future research should examine innovative models of care or treatment pathways supporting the identification and replacement of LvC in dementia.
    Type of Medium: Online Resource
    ISSN: 1387-2877 , 1875-8908
    URL: Article
    DOI: 10.3233/JAD-210439
    Language: Unknown
    Publisher: IOS Press
    Publication Date: 2021
    detail.hit.zdb_id: 2070772-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Oxidized organic molecules in the tropical free troposphere over Amazonia
    Oxford University Press (OUP) ; 2023
    In:  National Science Review
    Details
    In: National Science Review, Oxford University Press (OUP)
    Abstract: New particle formation (NPF) in the tropical free troposphere (FT) is a globally important source of cloud condensation nuclei, affecting cloud properties and climate. Oxidized organic molecules (OOMs) produced from biogenic volatile organic compounds are believed to contribute to aerosol formation in the tropical FT, but without direct chemical observations. We performed in situ molecular-level OOMs measurements at the Bolivian station Chacaltaya at 5240 m above sea level, on the western edge of Amazonia. For the first time, we demonstrate the presence of OOMs, mainly with 4–5 carbon atoms, in both gas-phase and particle-phase (in terms of mass contribution) measurements in tropical FT air from Amazonia. These observations, combined with air mass history analyses, indicate that the observed OOMs are linked to isoprene emitted from the rainforests hundreds of kilometers away. Based on particle-phase measurements, we find that these compounds can contribute to NPF, at least the growth of newly formed nanoparticles, in the tropical FT on a continental scale. Thus, our study is a fundamental and significant step in understanding the aerosol formation process in the tropical FT.
    Type of Medium: Online Resource
    ISSN: 2095-5138 , 2053-714X
    URL: Article
    DOI: 10.1093/nsr/nwad138
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2745465-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Reorganizing tasks in primary dementia care – A randomized, controlled, crossover intervention trial to test the efficacy and cost‐effectiveness of advanced nursing care in Germany
    Wiley ; 2022
    In:  Alzheimer's & Dementia Vol. 18, No. S9 ( 2022-12)
    Details
    In: Alzheimer's & Dementia, Wiley, Vol. 18, No. S9 ( 2022-12)
    Abstract: The increasing prevalence of dementia with the constant availability of general practitioners is a significant challenge for healthcare systems worldwide. Advanced nursing practice (ANP) was implemented in several countries as one possible solution to overcome this challenge. However, this concept of care is not yet implemented in Germany. The InDePendent study (“Advanced nursing practice and interprofessional dementia care”) is the first study in Germany, aiming to implement and evaluate a model of ANP for persons with dementia (PwDs) living at home and their caregivers where tasks were reorganized between dementia‐specific qualified nurses and physicians. Methods The Independent study is a multi‐center, cluster‐randomized, controlled, crossover interventional trial. Whereas the waiting‐control group receive care as usual, the InDePendent intervention of the intervention group aims to provide optimum care for PwD and their caregivers by integrating multimodal strategies of an individualized care within the framework of the German healthcare system by a reorganization of tasks between general practitioners and nurses. Dementia‐specific qualified nurses, who passed a specific state exam, conduct the interventions. Based on evidence‐based guidelines a comprehensive set of 115 intervention modules were defined. Each module consists of predefined trigger conditions and recommendations of actions. The intervention starts with a set of assessment instruments for PwD to identify the unmet needs, individual situation and resources of PwD and caregiver. Subsequently, an intervention tasks list was generated to address each of the identified unmet needs. The tasks lists were carried out by the dementia‐specific nurse in close cooperation with general practitioners. For the first time in Germany, nurses were able to carry out tasks that are usually carried out by general practitioners, like prescription of care aids and outpatient care. Expected results: We expect statistically significant differences between waiting‐control‐group and intervention‐group across the primary (unmet needs) and secondary outcomes (quality of life, caregiver burden, acceptance, cost‐effectiveness). This study can provide evidence concerning the safety, efficacy, and cost‐effectiveness of ANP in Germany, supporting the implementation of the ANP concept into German routine care.
    Type of Medium: Online Resource
    ISSN: 1552-5260 , 1552-5279
    URL: Issue
    URL: Article
    DOI: 10.1002/alz.v18.S9
    DOI: 10.1002/alz.065327
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2201940-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Tasks and Activities of an Effective Collaborative Dementia Care Management Program in German Primary Care
    IOS Press ; 2022
    In:  Journal of Alzheimer's Disease Vol. 87, No. 4 ( 2022-06-14), p. 1615-1625
    Details
    In: Journal of Alzheimer's Disease, IOS Press, Vol. 87, No. 4 ( 2022-06-14), p. 1615-1625
    Abstract: Background: Recent studies have demonstrated the efficiency of collaborative dementia care, which aims to improve post-diagnostic support. However, tasks carried out of such models are currently unknown, hindering its implementation. Objective: To describe tasks of a collaborative model of dementia care, analyze the association between specific task subgroups and number of tasks with patients’ and caregivers’ characteristics and the impact of specific tasks on health-related quality of life (HRQoL). Methods: The analysis was based on 183 persons with dementia (PwD) who received dementia care management conducted by dementia-specific qualified nurses. A standardized, computer-assisted assessment was used to identify patients’ and caregivers’ unmet needs. Tasks carried out to address unmet needs were documented, categorized, and descriptively analyzed. We used multivariate regression models to identify socio-demographic and clinical factors associated with a specific subgroup of tasks or a higher number of tasks. Results: On average, 20.5 tasks were carried out per dyad (PwD and caregiver). 41% of tasks were categorized to cooperation with other healthcare providers, 39% to nursing care, and 19% to social support. Lower HRQoL and higher age, cognitive impairment, deficits in daily living activities, and depressive symptoms were significantly associated with a higher number of tasks. A higher number of cooperation tasks were associated with a higher gain in HRQoL. Conclusion: Patients’ characteristics and HRQoL significantly determine the intensity of collaborative care interventions. Variability of the intensity should be considered in developing future studies and in the implementation into routine care. ClinicalTrials.gov Identifier: NCT01401582
    Type of Medium: Online Resource
    ISSN: 1387-2877 , 1875-8908
    URL: Article
    DOI: 10.3233/JAD-215656
    Language: Unknown
    Publisher: IOS Press
    Publication Date: 2022
    detail.hit.zdb_id: 2070772-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Impact of Hearing Aids on Progression of Cognitive Decline, Depression, and Quality of Life Among People with Cognitive Impairment and Dementia
    IOS Press ; 2023
    In:  Journal of Alzheimer's Disease Vol. 92, No. 2 ( 2023-03-21), p. 629-638
    Details
    In: Journal of Alzheimer's Disease, IOS Press, Vol. 92, No. 2 ( 2023-03-21), p. 629-638
    Abstract: Background: Hearing loss is common in people with dementia (PwD) and a modifiable risk factor for cognitive decline. Recent studies revealed that hearing loss could cause social isolation and depression, which is associated with health-related quality of life (HRQoL). However, there is a lack of knowledge about the impact of the utilization of hearing aids on these outcomes. Objective: To assess whether hearing aids use might be positively associated with the progression of cognitive function, depression, and HRQoL among PwD. Methods: We analyzed two-year follow-up data from 258 PwD (≥70 years, living at home). Cognitive decline was measured with Mini-Mental Status Examination (MMSE), depression using Geriatric Depression Scale (GDS), and HRQoL with Quality of Life in Alzheimer’s Disease Scale (QoL-AD). The impact of hearing aid utilization on the progression of outcomes was assessed using multivariate regression models. Results: 123 patients had hearing loss (47.7%), from which n = 54 (43.9%) used hearing aids. Patients with hearing loss were older and had a lower HRQoL than those without hearing loss. Use of hearing aids in patients with hearing loss was associated with a lower increase in depressive symptoms (b = –0.74, CI95 –1.48 ––0.01, p = 0.047) over time as compared to those not using hearing aids. There was no effect on PwD’s cognition, and the association with higher HRQoL was significant after one, but not consistently over two years. Conclusion: Early detection and intervention of presbycusis using hearing aids might improve mental health and HRQoL in dementia.
    Type of Medium: Online Resource
    ISSN: 1387-2877 , 1875-8908
    URL: Article
    DOI: 10.3233/JAD-220938
    Language: Unknown
    Publisher: IOS Press
    Publication Date: 2023
    detail.hit.zdb_id: 2070772-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Translation of Collaborative Dementia Care Management into Different Healthcare Settings: Study Protocol for a Multicenter Implementation Trial (DCM:IMPact)
    IOS Press ; 2022
    In:  Journal of Alzheimer's Disease Reports Vol. 6, No. 1 ( 2022-10-13), p. 617-626
    Details
    In: Journal of Alzheimer's Disease Reports, IOS Press, Vol. 6, No. 1 ( 2022-10-13), p. 617-626
    Abstract: Background: Collaborative care models for people living with dementia (PwD) have been developed and evaluated, demonstrating safety, efficacy, and cost-effectiveness. However, these studies are based on heterogeneous study populations and primary care settings, limiting the generalizability of the results. Therefore, this study aims to implement and evaluate collaborative care across various healthcare settings and patient populations. Objective: To describe the study design of this multicenter implementation trial. Methods: This single-arm, multicenter, longitudinal implementation study will be conducted in five different healthcare settings, including 1) physicians’ networks, 2) dementia networks, 3) counselling centers, 4) hospitals, and 5) ambulatory care services. Eligibility criteria are: having a formal dementia diagnosis or having been screened positive for dementia and living community-dwelling. The staff of each healthcare setting identifies patients, informs them about the study, and invites them to participate. Participants will receive a baseline assessment followed by collaborative individualized dementia care management, comprising proven safe, effective, and cost-effective modules. Over six months, specially-qualified nurses will assess patients’ unmet needs, transfer them to individualized care plans, and address them, cooperating with various healthcare providers. A follow-up assessment is conducted six months after baseline. Approximately 60–100 PwD per setting per year are expected to participate. Differences across settings will be assessed regarding acceptability, demand, implementation success and barriers, efficacy, and cost-effectiveness. Results: We expect that acceptability, demand, implementation success and barriers, efficacy, and cost-effectiveness will vary by patients’ sociodemographic and clinical characteristics and unmet needs in each setting. Conclusion: The results will provide evidence highlighting differences in the implementation of collaborative care in various healthcare settings and demonstrating the settings with the highest need, best conditions for a successful implementation, and highest (cost-)effectiveness, as well as the population group that benefits most from collaborative care. Trial registration: German Clinical Trials Register: DRKS00025074. Registered 16 April 2021-retrospectively registered.
    Type of Medium: Online Resource
    ISSN: 2542-4823
    URL: Article
    DOI: 10.3233/ADR-220045
    Language: Unknown
    Publisher: IOS Press
    Publication Date: 2022
    detail.hit.zdb_id: 2955863-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    p -Hydroxyacetophenone Amides from Cystobacter ferrugineus , strain Cb G35
    American Chemical Society (ACS) ; 2011
    In:  Journal of Natural Products Vol. 74, No. 6 ( 2011-06-24), p. 1358-1363
    Details
    In: Journal of Natural Products, American Chemical Society (ACS), Vol. 74, No. 6 ( 2011-06-24), p. 1358-1363
    Type of Medium: Online Resource
    ISSN: 0163-3864 , 1520-6025
    URL: Article
    DOI: 10.1021/np1006789
    RVK:
    WA 15000
    Language: English
    Publisher: American Chemical Society (ACS)
    Publication Date: 2011
    detail.hit.zdb_id: 1491522-4
    SSG: 12
    SSG: 15,3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...