In:
Journal of Clinical Microbiology, American Society for Microbiology, Vol. 32, No. 3 ( 1994-03), p. 846-847
Abstract:
The X region of the protein A gene of Staphylococcus aureus contains a highly polymorphic sequence which is composed of repeats of 24 bp. We used amplification by PCR to investigate whether this region could be used to discriminate between epidemic and nonepidemic methicillin-resistant S. aureus (MRSA) strains. Most epidemic MRSA strains (24 of 33) harbored more than seven repeats, while most nonepidemic MRSA strains (10 of 14) contained seven or fewer repeats. It is conceivable that a longer X region results in a better exposition of the Fc-binding region of protein A, thereby facilitating colonization of host surfaces and contributing to the epidemic phenotype.
Type of Medium:
Online Resource
ISSN:
0095-1137
,
1098-660X
DOI:
10.1128/jcm.32.3.846-847.1994
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
1994
detail.hit.zdb_id:
1498353-9
SSG:
12
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